ID A0A1S3MAA0_SALSA Unreviewed; 1953 AA.
AC A0A1S3MAA0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Afadin-like isoform X5 {ECO:0000313|RefSeq:XP_013999896.1};
GN Name=LOC106571391 {ECO:0000313|RefSeq:XP_013999896.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013999896.1};
RN [1] {ECO:0000313|RefSeq:XP_013999896.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013999896.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013999896.1; XM_014144421.1.
DR STRING; 8030.ENSSSAP00000042901; -.
DR PaxDb; 8030-ENSSSAP00000042901; -.
DR OrthoDB; 2881454at2759; -.
DR Proteomes; UP000087266; Chromosome ssa15.
DR GO; GO:0005911; C:cell-cell junction; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd22711; FHA_AFDN; 1.
DR CDD; cd15471; Myo5p-like_CBD_afadin; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01782; RA1_Afadin; 1.
DR CDD; cd01781; RA2_Afadin; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR028842; Afadin.
DR InterPro; IPR037977; CBD_Afadin.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10398; AFADIN; 1.
DR PANTHER; PTHR10398:SF2; AFADIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00788; RA; 2.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00314; RA; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50200; RA; 2.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 38..133
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 242..336
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 641..888
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT DOMAIN 985..1071
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 135..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1147..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1303..1576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1618..1775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1787..1878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1897..1919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1110..1125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1303..1336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1358..1389
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1398..1434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1440..1457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1458..1486
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1487..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1639..1728
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1731..1767
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1836..1850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1851..1865
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1953 AA; 220968 MW; 85A7AD5DA7246631 CRC64;
MSGSREEERR KLADIINHWN ANRLDLFEIS QPTEDLEFHG VMRFYFQDRV AGNFATKCIR
VSSTATTQDV IETLAEKFRP DMRMLSSPKY SLYEVHVSGE ERKLDLDEKP LVVQLNWNKD
DREGRFVLKN ENDIIPKKAQ SNGPEREKEG VIQNFKRTLS KKEKKKEKKR EKEAHIADGD
EQALSREDGE NSRLAAEVYK DMPENSFTRT ISNPEVVMKR RRQQKLEKRM QEFRSSDGRP
DSGGTLRIYA DSLKPNIPYK TILLSTTDMA DFAVVEALEK YGLEKENPRE YCIARHTDDK
SGKEIILDDT ECPLQIFRDW PNDRGDLVFQ LKKRPPDYVP KKGRKPEDKG PRGKGMDVPL
HGSLPPEKLP YLVELSPGRG NHYGYYTYRH HEDGSDSRDK PKLYRLQHSV TEVGSDTTDD
GSIQLFGPGI LPHHCKLMHT EGLVTVTPHS LEAETYVDGQ RVAETTVLRS GATLQFGASH
VFKFVDPSYD HSMGKGGPGP MMRGRHKSGS VPEATFDLQG DLHSGTALST SKSSGKLEME
RSSNGSERGM VKPMIRGEQQ DSRSQDSLSP EVTLPASIEF RDNSEDTFLT AIINYTNSST
VHFKLSPTYV LYMTCRYVMS SHYRPDIGPS ERTHKVIAIV NKMVSMMEGV IQEIPEADQK
QKNIAGSLAF WMANASELLN FIKQDKDLSR ITLDAQDVLA HLVQMAFKYL VQCLQSDLSN
YMPAFLDDPE EQNPQRPKIE DVLHTLTGAM SLLRRCRVNA ALTIQLFSQL FHFINMWLFN
KLVMEADSGL CSHYWGAILR QQLSHIEAWA EKQGLELAAD CHLSRIVQAT TLLTMDKYSM
QDVQNIHNTC FKLNSLQLNA LMTNYHCAPD EPYIPPELID HVVAVAENTA DELARSDGRE
VQLEEDPDLQ LPFLLPEDGY SCDVVRNIPN GFQEFLDPLC QRGFCRLTPH PRSPGTWTIH
FEGVDCDSHF SADNSDLQMR KEPEVVTVTL KKHNGMGLSI VAAKGAGQEK LGIYIKSVVK
GGAADVDGRL AAGDQLLSVD GRSLVGLSQE RAAELMTRTG SVVTLEVAKQ GAIYHGLATL
LNQPSPMMPR ASQGGRDKNG KLRPKSEGFE LYNNSVQNGS PESPQADWQA YPEPKKMSGE
ERLLKNRADH RSSPNVANQS QSPGGKAVYT RGPGTKITSV STGNLCVDDE PSPPHPEAYP
IPTQTYPREY FTIPASKSTN RMDPAPGQLY ADDRGPPGPM EDHHHNSIAM QRVDHSQEEL
CDLPGGYPPT SLRPEDLVHL HQQQQREADY QWGSGEHWVN HHQVSSSVES STSSQEHLNY
SSSSSNKTQS NHKSGPGRWK TPGPIAPHPG PVAQSTRTDL LPPPPPPPPV HYQDFELQPD
LPLPPPPSVT QQQAAAAAAD RKKREEQQRW YEKEKARLEE ERERKRREQE RKLGQVRNPA
VPVTHNNNQH GGTLPPPTQH QQVPPPRSPM QQVPPPRSPM QQVPHPYLPP QGQQQAQQQQ
PPRPEKLSTL PRAGTLPPQG NPMDTVIREL LPQQQPRTIE RRDLQYITIS KEELSSSDSL
SPDPWKRDAR EKLEKQQQLH IVDLLDREIQ DLQAKPERTA EESDRLRKLM LEWQFQKRLQ
ESKHSDEEDE EDDDEDVDTM MIMQRLEAEK RARLQDEERR RKQQLEEIRK REAEDRAKQE
EERRWREEER ARREVDEKRR QEEEYYTRLE EGRRRQHEEA ERKLLTPDEP GLYRPPLPRD
YQPQPPPPTA SPATTATNAP PPPPQRNTSY LKTQVVSPDA LYTAKFVSYN DEEDEDTTGL
AGQVKLSSTR KSYGDLPPAH KPQPPARKPR PMSDGIFLSS SFQPPAVNAN STAGQPPPPP
IKPSLIPTGN FKGFNSYTGN TTGVVVSGEV YKDLREKWTK GGQEQENTLT EGAPESMTFK
ERQRLFSQGK EVSNKVKASR KLMELENELN TKQ
//
