ID A0A1S3MFX1_SALSA Unreviewed; 768 AA.
AC A0A1S3MFX1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Segment polarity protein dishevelled homolog DVL-1-like isoform X1 {ECO:0000313|RefSeq:XP_014001964.1};
GN Name=LOC106572388 {ECO:0000313|RefSeq:XP_014001964.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014001964.1};
RN [1] {ECO:0000313|RefSeq:XP_014001964.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014001964.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DSH family. {ECO:0000256|ARBA:ARBA00008735}.
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DR RefSeq; XP_014001964.1; XM_014146489.1.
DR AlphaFoldDB; A0A1S3MFX1; -.
DR KEGG; sasa:106572388; -.
DR OrthoDB; 2910598at2759; -.
DR Proteomes; UP000087266; Chromosome ssa15.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd04438; DEP_dishevelled; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR024580; Dishevelled_C-dom.
DR InterPro; IPR008339; Dishevelled_fam.
DR InterPro; IPR003351; Dishevelled_protein_dom.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR015506; Dsh/Dvl-rel.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR PANTHER; PTHR10878:SF5; SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF02377; Dishevelled; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF12316; Dsh_C; 1.
DR Pfam; PF00595; PDZ; 1.
DR PRINTS; PR01760; DISHEVELLED.
DR PRINTS; PR01761; DISHEVELLED1.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 1..85
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT DOMAIN 271..343
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 432..506
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT REGION 89..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..561
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 768 AA; 83565 MW; 06A9D0164CA9CBF7 CRC64;
MAETKIIYHI DEEETPYLVK LSVSPEKVTL ADFKNVLNNR PVNSYKFFFK SMDQDFGVVK
EEISDDNAKL PCFNGRVVSW LVLAESSHSD GGSQCTESHP ELPPPLERTG GIGDSRPPSF
HANAVSSRDG LDTETGTESL LSHRRERERE RARRRARETE IPRINGHSKS ERTARDSAMG
YDSASVMSSE LESSSFVDSE EDEDASRGAA LRLTLCCSQP AVLSSSTEQS SSSQLMRRHK
RRRRRHKVAK IDRSSSFSSI TDSTMSLNII TVTLNMEKYN FLGISIVGQS NDRGDGGIYI
GSIMKGGAVA ADGRIEPGDM LLQVNDVNFE NMSNDDAVRI LREIVSKTGP ISLTVAKCWD
PSPRSYFTIP RGKTLTDVPP TTAEPVRPID PAAWISHTTA LTGPYPHYEF DDLPLSASKT
DISTIVKVMQ LPDSGLEIRD RMWLKITIGN AVIGADVVDW LYSRVEGFKD RRDARKYASS
LLKHGYLRHT VNKITFSEQC YYTFGDLCQN MASLNLNEGS SGGGSEQDTL APLPPPATNP
WPLGGQPFPY PPFPSAPAGF PPGYSDPCHS FHSGSAGSHN SEGSRSSGSN PSVGTGTGKG
PSRRSSPQEK GHRSTCSESE PPGILGARRP GDRSASQLSH HSSHAHSSNS HARSGFSHAQ
SHRSHCHSQN SHAHSHASFT YKYAPFTQPG LGSCGHSERS HASSYGPPGL PPPYCLARLA
PKTSVSSSTP PGAPPVRELG AVPPELTASR QSFQHAMGNP CEFFVDIM
//
