ID A0A1S3MG97_SALSA Unreviewed; 1884 AA.
AC A0A1S3MG97;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Plexin-A1-like isoform X2 {ECO:0000313|RefSeq:XP_014001921.1};
GN Name=LOC106572368 {ECO:0000313|RefSeq:XP_014001921.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014001921.1};
RN [1] {ECO:0000313|RefSeq:XP_014001921.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014001921.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_014001921.1; XM_014146446.1.
DR STRING; 8030.ENSSSAP00000096649; -.
DR PaxDb; 8030-ENSSSAP00000096649; -.
DR GeneID; 106572368; -.
DR OrthoDB; 1387371at2759; -.
DR Proteomes; UP000087266; Chromosome ssa15.
DR Bgee; ENSSSAG00000065515; Expressed in brain and 14 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd00603; IPT_PCSR; 1.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01179; IPT_plexin_repeat2; 1.
DR CDD; cd01181; IPT_plexin_repeat3; 1.
DR CDD; cd12790; RasGAP_plexin_A; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF35; PLEXIN-A1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 3.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 4.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 4.
DR SMART; SM00423; PSI; 3.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 4.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 2.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1884
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010356737"
FT TRANSMEM 1231..1255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..502
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT COILED 1252..1301
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1884 AA; 210644 MW; 01B6EA4F0D34F582 CRC64;
MTSHPTPPLG GPLLPFLLLL SGVFATTPSD LRSFSPPEGG LTHLVVHNKT GEVYLGAVNW
IFKLSSNLTK LRSHVTGPVV DNEKCYPPPG VQSCPHELTQ ISNVNKLLLL DYGQNRLIAC
GSTSQGICQF LRLDDLFKLG EPHHRKEHYL SSVAEAGTMS GVVIGGDAAG SGGEAGKLFV
GTPIDGKSEY FPTLSSRKLM DNEENADMFS FVYQDEFVSS QLKIPSDTLS KFPAFDIYYI
YGFSSEQFVY YLTLQLDTQL TSPDASGEQF FTSKIVRLCV DDPKFYSYVE FPIGCTKDGV
EYRLVQDAYL SRPGTKLARS LGISEQEEVL FTVFAQGQKN RAKPPKESAL CLFTLRRIKE
KIKERIQSCY RGEGKLSLPW LLNKELACIN SPLQIDDNFC GQDFNQPLGG TSTIEGLPLF
VDKDDGMTSV AAYEYRGHTV AFAGTRSGRI KKILVNSVNQ PAMLYENVAV SEGSPIHRDL
LFSPDHQHIY ALTDKQVSRV PVESCEQYSS CSACLGSGDP HCGWCVLHNV CSRKDRCERA
DEPQRFASRV EQCVKLSVQP GNISVTMSEV QLVLQAQNVP NLSAGVNCSF EDYTETEGRI
FGGRIYCLSP STREVAPITR NQGDKRTVKL YLKSKETGKK FASVDFVFYN CSVHQSCLSC
VNGSFPCHWC KYRHMCTQNA NDCSFQEGRV NMSEECPQIL PSTQIYIPVG VMKPITLLAK
NLPQPQSGQR NYECIFHIQG ATYSVTALRF NSTSIQCQRT SYDYDGNDIS DLPVDLSVVW
NGNQVIDNPF NIQAHLYKCY ALRDSCGMCL KADPRFECGW CVQEKKCSLR QECAPLESSW
MHATAGNSRC THPKITKLFP ETGPRQGGTR LTITGENLGL QFRDIQTGVH LGKVPCIPIE
EEYISSERIV CLLNDATGYR VQEANVEVCV RDCLADYRAL SPRAFTFVTP FFTRVLPAQG
PLSGGTRITI EGNHLNAGSS VSVNIGRHLC HFKKRNSREI VCVTPAGLTP GSTPVMVDID
SAELRNPEVK YNYTDDPTVL RIEPDWSIAS GGTLLTISGT NLATIREPKI RAKYGSAESF
HNCTVFNNSV MVCLAPSVAD SERGFSDTGS GPDEIGFYMD NVHALMVVNE TFSYYPDPVF
ELLSPTGVLE LKPTSPLILK GRNLIPAAPG NSRLNYTVFI GETPCVLTLS ETQLLCEWPN
LTGQHKVTVR VGGFEYSPGT LQIYSDSLLT LPAIIGIGGG GGLLLLVIIA VLIAYKRKSR
DADRTLKRLQ LQMDNLESRV ALECKEAFAE LQTDIHELTQ ELDGAGIPFL EYRTYAMRVL
FPGIEDHPVL KEMEVQANQE KALTLFGQLL TKKHFLLTFI RTLEAQRSFS MRDRGNVASL
IMTALQGEME YATGVLKQLL SDLIDKNLES KNHPKLLLRR TESVAEKMLT NWFTFLLYKF
LKECAGEPLF MLYCAMKQQM EKGPIDSITG EARYSLSEDK LIRQQIDYKT LTLHCVNPEN
ENAPEVTVKG LNCDTITQVK EKLLDAVYKG SPYSQRPKAG DMDLEWRQGR MARIILQDED
VTTKIDNDWK HLNTLAHYQV TDGSVIALVP KQNSAYNISN SSTFTKSLSR YESMLRTASS
PDSLRSRTPM ITPDLESGTK LWHLVKNHDH SDQREGDRGS KMVSEIYLTR LLATKGTLQK
FVDDLFETIF STAHRGSALP LAIKYMFDFL DEQADKHSIS DSDVRHTWKS NCLPLRFWVN
VIKNPQFVFD IHKNSITDAC LSVVAQTFMD SCSTSEHKLG KDSPSNKLLY AKDIPNYKNW
VERYYSDISR MPAISDQDMS AYLAEQSRLH LSQFNSMSAL HEIYSYIVKY KDEILSSLQK
DEQSRRQRLR SKLEQVIDTM ALAS
//
