ID A0A1S3MHK1_SALSA Unreviewed; 2150 AA.
AC A0A1S3MHK1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Plexin-B1-like isoform X1 {ECO:0000313|RefSeq:XP_014002662.1, ECO:0000313|RefSeq:XP_014002663.1};
GN Name=LOC106572747 {ECO:0000313|RefSeq:XP_014002662.1,
GN ECO:0000313|RefSeq:XP_014002663.1, ECO:0000313|RefSeq:XP_014002664.1,
GN ECO:0000313|RefSeq:XP_014002665.1, ECO:0000313|RefSeq:XP_014002666.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014002662.1};
RN [1] {ECO:0000313|RefSeq:XP_014002662.1, ECO:0000313|RefSeq:XP_014002663.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014002662.1,
RC ECO:0000313|RefSeq:XP_014002663.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_014002662.1; XM_014147187.1.
DR RefSeq; XP_014002663.1; XM_014147188.1.
DR RefSeq; XP_014002664.1; XM_014147189.1.
DR RefSeq; XP_014002665.1; XM_014147190.1.
DR RefSeq; XP_014002666.1; XM_014147191.1.
DR STRING; 8030.ENSSSAP00000099371; -.
DR PaxDb; 8030-ENSSSAP00000099371; -.
DR GeneID; 106572747; -.
DR KEGG; sasa:106572747; -.
DR OrthoDB; 1387371at2759; -.
DR Proteomes; UP000087266; Chromosome ssa15.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd12793; RasGAP_plexin_B1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF59; PLEXIN-B1 ISOFORM X1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 2.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 2.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..2150
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010813964"
FT TRANSMEM 1508..1528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..478
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 798..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..824
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2150 AA; 236940 MW; A0D43316DCE793B4 CRC64;
MRLGMSLISA LLVFLLVTTT CSLAVCTYPR FSRNDSSFEH LVLHPDPSVG TVYVGARDHL
FQLDGLDGLR LEQEERTGPV TDSKECLPPV TEANCPQARH TSNHNKLLLV DPSAMELITC
GNVHQGTCQK RSLTSVKEVL FSTERPVDTQ YVAANDPVVS TVGLVVGPRG EERAVLYVGR
GYTSSHPPIS TRHLAHEPVF SYDETAKLAV AERLSEYDHH FVAAFARLGH VYFLFYRRDI
KAVTREYRTY AARMCLDDTS YYSYVEVPLV CHTTSSPERN YNLLQAAQVG QGGGKEGEKL
LGVFSTQASS SNGPSDDSAL CVYPLDELDR HIDSTRDLCY TQDGRVEGGG EVAYIEYEVK
SSCANLPTNT LKAYPCGSDH TPSPMASRVP IEAEAVLDSP SARLTAVAVS VRAGHTIAFL
GDSKGNLHKV FLGSGGRVEK YSSILIQPNS PISSDLLLDQ METHIYIMTS TMVEKRPVAE
CGDHLDCQSC VSAREPYCGW CVLEGRCGQR SQCSRGALQG QWLWSFDQQQ QCLSIQSLSL
YNISLGVETD IAVSVKGLPS LVEGEAYKCF YQDVESPANV TDTGVTCSTP DASRLPLIGQ
GEDSVTVPLS LRFLNVTVAA WEFTFFDCGV VQQLSGGMPC RGCVSSRWGC NWCIHQHFCT
WNISCDEGVT IYNKHLKPPT ATPPATKQSD TVTPTVLAAP TLPYTEVSDR TTLPVPASMG
VPLATPPTTP LTTLATQATT ALKVTASLQA GAIAEETKVE GDGDGSLPRT TGGTEQTTVT
RVELLDWPEA LETVFPSSTA GLTGLTGTEP SSPDTTSTIS SGVPLLVDLP TGSDRDEIPL
APFQGTASPP WTREWDKGEG KTETKMEPAT SSATVPSGVD DSNQPSQSFT LTPDPESSPD
YQSDSFALQD CPCVEKVQGP SLLPVNVERK ITLVGRHLHL FQDEDLDYEC VLTIEGRSVV
VDADVETEDT QPSLYIITCQ LHQYAYTASA EEYDAVINVR RRDTFQIDSA DDLHVTLFNC
SVGRSDCSRC RTAHQKYGCV WCGGARSRCS YRDSCAGDIK QSCPGPVIHF MEPISGPVDG
GTVVTISGSN LGQKAEDIQN SVTIAGVPCT VINSRYEISS RIVCETTASG GQKSGQASVE
VRGGGLGFSG QRFSFQDPVL MEIAPQKGPK AGGSALTVMG QSLKTGHLSE VSVLIGGVPC
LISSEVMDDQ ITCMTGGSNR TGAHRITVRF GRAVRHLEGD VYYYTSDPNV TMATPSKSFL
SGGRLIHVSG QNLDVVQEPR IRVTLSPLES LSPRKKRRMR RSSRDGESRV RCKDIPLKRQ
RRIVPEPDCP EDMLCVVKQF ETRCAVSSSS LMLCPTPAVG TKAHNARVKV DFLLDNLHFD
FSAVGSGAFS YELNPILIPL NQNDPSKPYQ HKPGSIISVE GENLDLAIFK EEVVALIGDG
VCSVKTLTHN HLYCEPPSQQ PSVMASKKQE GMDSLPEFTV QMGNLNFSLG RVQYDTQVQS
TFPLEAQVGV GVGASIVALI VLVIVLIYRR KSKQAVRDYK NVQIQLENLE TSVRDRCKKE
FTDLMTEMMD CSSDLVGSGI PFLDYRVYAE RIFFPGHRES PLRRDLDVPE CRRQTVEQGL
VQLSNLLNSK LFLTTFIHTL EVQRTFSPRD RAYVASLLTV ALHGKLEYFT DILKTLLNDL
VVQYMAKNPR LMLRRTESVV EKLLTNWMSM CLFTFLRDTA GESFYMLFRA IKHQVDKGPV
DVVTGKAKYT LNDNRLLRED IDYKTLTLNV LMPATGNGGV PQTAPAKVLD CDTITQVKEK
LLEQAWKGMS FSQRPHTDSL HLEWRAGTAG HLILSDEDLT SVVQGSWKRL NTLHHYKVPD
GATVALVPRN TKHVHNDSHD YIPGEKTPML DDGDEGGMKL WHLVKANEEP DVPKHRRGSL
KERERAKAIP EIYLTRLLSM KGTLQKFVDD LFTVILSTNQ TVPTAVKYFF DLLDEQALQH
NITDSETIHI WKTNSLPLRF WINILKNPQI IFDVQASDHV DAVLSVIAQT FMDSCTIAEH
KLGRDSPINK LLYARDIPRY KQMVERYYAD IKQTISASDQ EMNSALAELS RNYAGEVNYL
VALHELYKYI NKYYDQIITA LEEDSTAQKM QLGYRLQQIS AAVENKVTDL
//
