ID   A0A1S3MK94_SALSA        Unreviewed;       973 AA.
AC   A0A1S3MK94;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Transcription initiation factor TFIID subunit 4-like isoform X4 {ECO:0000313|RefSeq:XP_014003648.1};
GN   Name=LOC106573262 {ECO:0000313|RefSeq:XP_014003648.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014003648.1};
RN   [1] {ECO:0000313|RefSeq:XP_014003648.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014003648.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF4 family.
CC       {ECO:0000256|ARBA:ARBA00006178}.
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DR   RefSeq; XP_014003648.1; XM_014148173.1.
DR   AlphaFoldDB; A0A1S3MK94; -.
DR   GeneID; 106573262; -.
DR   OrthoDB; 2910924at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa16.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR   CDD; cd08045; TAF4; 1.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR045144; TAF4.
DR   InterPro; IPR007900; TAF4_C.
DR   InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR   InterPro; IPR003894; TAFH_NHR1.
DR   PANTHER; PTHR15138:SF22; TAFH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR   Pfam; PF05236; TAF4; 1.
DR   Pfam; PF07531; TAFH; 1.
DR   SMART; SM00549; TAFH; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
DR   SUPFAM; SSF158553; TAFH domain-like; 1.
DR   PROSITE; PS51119; TAFH; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          528..625
FT                   /note="TAFH"
FT                   /evidence="ECO:0000259|PROSITE:PS51119"
FT   REGION          156..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          858..936
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        858..879
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        912..936
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   973 AA;  102005 MW;  BB5E2D28020714B7 CRC64;
     MAGASDPLED MLFNEVDEKA VSDLVGSLES QLVSQKTSPA TYSDIKREGS TGTVSQFSGK
     VRDQVGSLEP PQQGHPKAVL NAEPCANQAI SNKSITASTS SITTGGIINA GTNLQTHGVA
     SRIISPAPPG SVTLPAQTTS FNRGTVLGPA ETSVVTAPNS NLTTTTTTTT TAIRTPSPGL
     QSFNGSAGAV KLVNSPAAAP QTGSGGNTVI STASAGNSNI IVSMASQPPS LPNYPVSQSA
     VAFVTPAVAL QRHPNPMASA SQNGLVDLKV SAVDTQGAGS PGVTTSQVMN RNNTLINTTV
     VAPNQPVSAD QSIILGGSPA PVVNSPVNQA QSVASPTLTA GVKPTVNGVG QSTVTIVRPP
     GAPVMATSVQ QQRPGLVASP TRTVAPQMVV RPPQQTTIQL PPGFTIPPGM VLVRTDTGQL
     VMVPQQVLAQ AQAKTQQGQA AVSNISPRPA TPTAGATIRV STPSQAITVA PVSVKMTTPQ
     KAQTVITGGQ ALAKPGAVRP SITLNTAAAA SASTTPTVVT SPVSQEMQEN VKKCKNFLAT
     LIKLASHNSP SPDTSKNVKA LVQDLLDAKI EPEEFTTRLQ AELKSSPQPY LIPFLKKSLP
     ALRLSLLNNQ QSLLASTNAS ALAAASTTTT STIRARFPTT VSPATGIVRT PTTALGVRRP
     GVQGVQTRMP MVIPQTIRPQ GTVARGLTII AGRSPVGIGA QASANQKKLN EPGGGTFRDD
     DDINDVASMA GVNLNEENAR IMATNSELVG TKIRSCKDEA FLPPGLLHRR IMETAKRFGV
     TEVPAEAVNY ISHATQARLR SMLEKVSTIA QHRTDGGKDE EWYEPSTDVR AQLRFFEQLD
     RMEKQRKDEQ EREVLLKAAK SRARQEDPEQ ARLKAKAKEM QQAEQAQIRQ REANLTALAA
     IGPRKKRKMD SPGSSTSGTE VALGSGAGSS TAASSRQQLR QRITRVNLRD FIFCLEQERA
     TSRSLLLYKA LLK
//