ID A0A1S3MLD2_SALSA Unreviewed; 203 AA.
AC A0A1S3MLD2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Uncharacterized protein LOC106573458 {ECO:0000313|RefSeq:XP_014003997.1};
GN Name=LOC106573458 {ECO:0000313|RefSeq:XP_014003997.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014003997.1};
RN [1] {ECO:0000313|RefSeq:XP_014003997.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014003997.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Inflammasome {ECO:0000256|ARBA:ARBA00004110}.
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DR RefSeq; XP_014003997.1; XM_014148522.1.
DR AlphaFoldDB; A0A1S3MLD2; -.
DR KEGG; sasa:106573458; -.
DR OrthoDB; 3794276at2759; -.
DR Proteomes; UP000087266; Chromosome ssa16.
DR GO; GO:0061702; C:canonical inflammasome complex; IEA:UniProtKB-SubCell.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08330; CARD_ASC_NALP1; 1.
DR CDD; cd08321; Pyrin_ASC-like; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR033516; CARD8/ASC/NALP1_CARD.
DR InterPro; IPR004020; DAPIN.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR PANTHER; PTHR46985:SF2; APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD; 1.
DR PANTHER; PTHR46985; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF02758; PYRIN; 1.
DR SMART; SM01289; PYRIN; 1.
DR SUPFAM; SSF47986; DEATH domain; 2.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50824; DAPIN; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023233};
KW Inflammasome {ECO:0000256|ARBA:ARBA00023233};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 1..91
FT /note="Pyrin"
FT /evidence="ECO:0000259|PROSITE:PS50824"
FT DOMAIN 109..199
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
SQ SEQUENCE 203 AA; 22676 MW; C693A5E7A4B31142 CRC64;
MATPVPQRLL ATLEKLDKAT FETFQWNLME ETLEGFNPMS IANLEDASRH KTVSKMVQAY
KKEGAMKITQ KILENMGIID LADKLKTDVE KDQAATPQSS QDQSAVMETK QYGAQFVDDN
MDKLVQRITM VMPIADGLYQ KKMIHDEDYS EITAAQTSMS KMRKLYVALK PGGAEAKSAF
YKILLDQHPL LVKELAGLGP AEG
//
