ID A0A1S3MM79_SALSA Unreviewed; 812 AA.
AC A0A1S3MM79;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|RefSeq:XP_014004287.1};
GN Name=LOC100380741 {ECO:0000313|RefSeq:XP_014004287.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014004287.1};
RN [1] {ECO:0000313|RefSeq:XP_014004287.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014004287.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_014004287.1; XM_014148812.1.
DR AlphaFoldDB; A0A1S3MM79; -.
DR STRING; 8030.ENSSSAP00000073567; -.
DR PaxDb; 8030-ENSSSAP00000073567; -.
DR Ensembl; ENSSSAT00000106875; ENSSSAP00000073567; ENSSSAG00000063844.
DR GeneID; 100380741; -.
DR KEGG; sasa:100380741; -.
DR OMA; CKVCKAD; -.
DR OrthoDB; 5487at2759; -.
DR Proteomes; UP000087266; Chromosome ssa16.
DR Bgee; ENSSSAG00000063844; Expressed in brain and 12 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 6.20.200.20; -; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR24042; NEL HOMOLOG; 1.
DR PANTHER; PTHR24042:SF0; PROTEIN KINASE C-BINDING PROTEIN NELL2; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF02210; Laminin_G_2; 1.
DR Pfam; PF00093; VWC; 2.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 6.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SMART; SM00214; VWC; 4.
DR SMART; SM00215; VWC_out; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57603; FnI-like domain; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Kinase {ECO:0000313|RefSeq:XP_014004287.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_014004287.1}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..812
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010161020"
FT DOMAIN 55..226
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 270..329
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 439..477
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 481..521
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 522..552
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 554..589
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 601..636
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 637..692
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 697..755
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DISULFID 524..534
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 542..551
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 812 AA; 90225 MW; 421B1D8439C49B02 CRC64;
MGLKIFICLG LFCVTSVLGF GIDPALCINV FDELTLGDGF DGVTQVQGFH SESRAFHFQG
SSREVKAPED VSERMLQKLR GRREFTVVVT LKQEHFNSGV ILSIHHSEQR FLELESSGQR
NEVRLHYRTK GQKAHTEVFP YSLADGQWHK VSVAVSASHI ILHVDCNRIY ERVVEIPFMD
IPEDTTFWLG QRSSTHGFFK GVMQDVQILV MPQGFISQCP DLNRTCPTCN DFHGLVQKIM
ELQDILAKTS SKLSRAEEMM NGLDGCYCER TCSVKGVVYR EDESLTDGCR NCTCTNGTVQ
CETISCPPPQ CPADTTPAYV KGACCMECQP VCHFGEEELV EGDQKAVHYN SGRCQLSECR
ERTMHRVVMT SPCPELNCPE SEQITLTDRC CKVCRGHDFC AEGHGCVEHS DCINLEAGAC
CSCKDGFRPL RDDNAYCEDI DECAEGKHYC RENTMCVNTA GSFMCVCHTG YIRIDDYCCT
EHDECVSGLH SCAQNALCFN TVGGHSCSCK PGYTGNGTIC KAMCDGLCQN GGTCISPNNC
ICQLGFTGKM CETDIDECFH GFVECDDKAI CVNLPGWYHC ECRDGYHDNG LFSTNGESCI
DINECKTGRN TCANDTVCFN LEGGYDCRCP HGRNCTGDCI HDNKVKHNGQ IWVLDNDRCS
VCSCQTGRVM CRRMVCDCEN PTADLFCCPE CDPRLSSQCL HQNGLLTYGS GDTWVENCQQ
CQCLQGQVDC WPLLCPHVDC EFTVVPEGEC CARCVTDPCQ ADTIRNNITK TCMDEHGIQR
FSGSSWVKHS TECTLCQCKN GHICCSMDPM CL
//
