ID   A0A1S3MPV0_SALSA        Unreviewed;       655 AA.
AC   A0A1S3MPV0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Cyclic nucleotide-gated channel cone photoreceptor subunit alpha-like isoform X2 {ECO:0000313|RefSeq:XP_014005207.1};
GN   Name=LOC106574120 {ECO:0000313|RefSeq:XP_014005207.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014005207.1};
RN   [1] {ECO:0000313|RefSeq:XP_014005207.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014005207.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   RefSeq; XP_014005207.1; XM_014149732.1.
DR   AlphaFoldDB; A0A1S3MPV0; -.
DR   GeneID; 106574120; -.
DR   CTD; 567242; -.
DR   OrthoDB; 74296at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa16.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 1.20.5.300; -; 1.
DR   Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR032406; CLZ_dom.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR45638:SF6; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3; 1.
DR   PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR   Pfam; PF16526; CLZ; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        277..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          453..567
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   REGION          1..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..125
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   655 AA;  76277 MW;  E7FB6E08E99253E7 CRC64;
     MLRTWASHRM HREVERLDSF PERFRTPELK ETPSSRESNA RSQGYPDRIR KRNQVSQWPL
     AMYNMNNCNN TDDKKDDKKD EIKKEEKKDE EKEKEEEPKK EEEPKKEEEP KKEEPKKEEK
     KKEEPPKEIW IMDPSTDHYY TWLTIIAAPC FYNLMMLVTR ACFNELQNTY TILWVVLDYT
     SDLVYYADTF VRSRTGYLEQ GLLVKDKQKL LDKYRQTEQF KWDVISMIPT DLLFLKVGIN
     NPELRLNRLA KMNRLFEYFD RTETRTSFPN VFRISNLVLY ILIIIHWNAC IFFAISKIIG
     FGSDSWVYPN ISHPEHGRLS RKYIYCLYWS TLTLTTIGET PPPVKDFEYL FVVADFLIGV
     LIFATIVGNV GAMISNMNKN RADFQAKIDS IKQYMQFRKV SKDLEARVIK WFDYLWTEKK
     TCDEKEVLKN LPDKLKAEIA IDVHLDTLKK VKIFQECEAG LLIELVMKLQ PQVFSPGDYI
     CKKGDIGREM YIIKEGKLAV VAEDGVTQWC VLSDGAYFGD ISILGIKGSK AGNRRTANIR
     SVGYSDLFAL SKDDLMEALT EYPEAKKILE EKGKATLMKD NMIDEEIANA GADPKDMEEK
     ILRLESNMEV MTSKLAKIMA EFTASQSKIK QRITSMETTV KSVRPEDISE VVADK
//