ID A0A1S3MQK5_SALSA Unreviewed; 1807 AA.
AC A0A1S3MQK5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein Shroom2-like isoform X1 {ECO:0000313|RefSeq:XP_014005467.1};
GN Name=LOC106574252 {ECO:0000313|RefSeq:XP_014005467.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014005467.1};
RN [1] {ECO:0000313|RefSeq:XP_014005467.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014005467.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
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DR RefSeq; XP_014005467.1; XM_014149992.1.
DR KEGG; sasa:106574252; -.
DR OrthoDB; 4120529at2759; -.
DR Proteomes; UP000087266; Chromosome ssa16.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014800; ASD1_dom.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF38; PROTEIN SHROOM2-LIKE ISOFORM X1; 1.
DR Pfam; PF08688; ASD1; 2.
DR Pfam; PF08687; ASD2; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51306; ASD1; 1.
DR PROSITE; PS51307; ASD2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00637};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 41..122
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 876..941
FT /note="ASD1"
FT /evidence="ECO:0000259|PROSITE:PS51306"
FT DOMAIN 1503..1800
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 170..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 973..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1058..1077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1082..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1395..1511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1543..1575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1592..1650
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1691..1747
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 174..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..219
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 996..1010
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1089..1103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1235..1297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1324..1379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1468..1494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1495..1511
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1807 AA; 199667 MW; 7E757C926DEA21F1 CRC64;
MDVVDYRSEL RMSAREVKAF LDADIFTAVG DRNKDDVEYR FVDVMLFGGA PWGFTLRGGL
EHREPLLITK VEEGSKAATV SLQVGDEIVN INTVPISGSR QEAVCLVKSS HKTLALVVRR
YLPNRDGMQY MAYIMKMKMV DIDSQTTMPS ESETDKHVAR NFLTKILRSS MRKNRFKGRN
EPVSRPHSWH SSKFTEDHPE PTESHNEPPP APPPPPVWQV KHEVSASTKD LSSCGDHDSN
LHQLSSQFSS VGNMERVERP SHPFPPGCLS PSRYHCSAEP LSGGGGSGGK RESAFSCLSS
TSPPPEPALA LADTAVTEGS MFYKGVQTQT SEDGRPGEQR HSRYLQLSQG DGGSESPRTV
PEEQPGSRYS SSGSGRSHIG PVWHVPERRR VAAPPSPPPP PLRSDSFAVT KVYPAYTEGP
GAPPHGQMKT QERGVDRLAE APENSSYRGR GNHISHDENG VDPRCSYNPP PRKKDFLHPN
IAAGAPDYNH NQLSNPNKLF SVSSQDVRRS QSPFACLPNH QRQYSDESTF YLQTRSAPHP
PKPQSVGSYY HSLQELPTNC SNSRNHVRSS TTSLSTSTID QSYDGGGHIR YYCITTKQPA
QPETRVRQSK SEVWRADMEL AKGSSDRGST SSSHKTNKVK YPPYPQQSYT NSKERNGNIQ
TANVLLYGHT TSNSLSSSGK PTTEEKERRS EGQRPSTEAQ LRSSYTPSPP KDHKAAPLRE
DPWVSQENHK ISSQKTPMLH SLAQESRSLV QESRSPMLHS LAQESKSLVE NNHPVTAPQP
PPSNGAGEAN HAIQEALTDN TATGKLARRS DRYATTLRNE IQLKRAQLQK SRSAATLTCP
SETEEPEEEE TDPGGWKSTS STSSDGSFSS SYKDHLKEAQ ARVLQATSFR RRDLEPPGSG
SEAPLTKPNS HIVSRIGGRK RFPLNKRVHS FSEPDKINKL GVEGEGEHPV GTARSFVDRR
KFFEMAAKPS FCRPNSTIHK SGQQSSSTTS STLEHGEGKA RGRAHSGETE ECWRPGLASE
TSSDHHSDPL SPAGRQALLE QQRLGTFAEY QVTWDMQRKA SDTKPQGRYH SADNILDQGT
EETSVCVHER SRSSPSQDFY SQIPVPWRDS VENPYLDHRQ DQQGGSYTTR GQSESREQPA
QLDHFPQPPQ PSIPRLTDTE PHSSRDVAAP LPHPSDHRYK RDSADPAHNL PALPPYPSNH
THSSVSEQPL PPPTLAPKPQ NTGLIIMPHW PLLGLETPST TSSSYGPSSQ EFLPGPCTHQ
AEPSSSSSCS PHGTELDPAP NQACSLGSTQ LPSPSPGRTA GLDTEEGAAD STLEPPPSPS
SHSPFFSYQP ASLTVPSGGT SSPSPQFAPQ RLTDQPPVSL SMQDEAQSRP ENRTNAVMEM
SSVGKKVPVK IVHVESTTER ESRQYLLHSE KNRALGVSEG PDLPSPLPTS LPSPEPQPYS
LFRAYTPYTR HGPQSPPRDP NLTVAPEEGL SPGQSETNGP SGTSTMGPQQ PQKSNSEEDV
KREELARDIM DKDKSLVDIL DQSKMKTTMD LMEGIFPQGE QILDGGHQRR KVSPKQGLPP
RGMDDRREEE GMSAATGSLV TSSSYYSTSA PKAELLNKMK DMQEDELEEL EQDSEDELDI
DLASKKQELI DSLGKKLQVL REARESLQED VHDNNSLGDE VEAMVQKVCK PNELDKFRMF
VGDLDKVVSL LLSLSGRLAR VENALNSLEE DTTPEEKRTL SEKRKLLIRQ HEDAKELKEN
LDRRERLVYS IMAAHLSHES LADYQHFVKM KSALIIEQRK LEDKIKLGEE QLKCLLDSLL
LEQRLLF
//
