ID A0A1S3MVE6_SALSA Unreviewed; 757 AA.
AC A0A1S3MVE6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rho GTPase-activating protein 6-like isoform X3 {ECO:0000313|RefSeq:XP_014007188.1};
GN Name=LOC106575282 {ECO:0000313|RefSeq:XP_014007188.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014007188.1};
RN [1] {ECO:0000313|RefSeq:XP_014007188.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014007188.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014007188.1; XM_014151713.1.
DR AlphaFoldDB; A0A1S3MVE6; -.
DR GeneID; 106575282; -.
DR OrthoDB; 5482290at2759; -.
DR Proteomes; UP000087266; Chromosome ssa17.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04376; RhoGAP_ARHGAP6; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR041852; ARHGAP6_RhoGAP.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR037863; RHOGAP6/36.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR12635:SF14; RHO GTPASE-ACTIVATING PROTEIN 6; 1.
DR PANTHER; PTHR12635; RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 226..427
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 111..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..702
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 84292 MW; C759CAED0F7A34C8 CRC64;
MGDSVFLERH NSYLGDFTWN SLSGRSVRLM PTAIQSLSEL ERTWLQEVAF NRLHQDYDLG
CQITIPKDGQ KRKKSLRRKL DSLAKEKNKD KECIPQAFGM ALSQVIANDR THRQRQDGLR
QDPPHREEHK DPSDLVSSIL QFATKRSTNK ELSSSNSSLS STSETANEST SPSTPEAAPR
ARRRGGMSVD SITDLDDNQS RLLEALQLSL PAEAPSKKEK HRDKRLSLNP IYRQVPRLVD
SCCQHLEKYG LQTVGIFRVG SSKKRVRQLR EEFDRGVDVQ LDEEHSVHDV AALLKEFLRD
MPDPLLTKEL YTAFINTMLL DCEEQRSATQ LLVYLLPACN SDTLHRLLQF LSTVANHAHD
SQDKEGQEVT GNKMTSLNLA TIFGPNLLHK QKSSDKEFSV QSSARAEEST AVIAVLQRMI
VTFHSLFMVP PDLQNEVLMS LLETDPDVVD YLLRRKASQS PDVLRSEDPF SLSERRCSSD
SNKVSSGELS PYDNNSPILS EHLREGTSPR SEQYTLVRQV AGRTRDTHGS NPWVSKEEHA
NIWGAWHSTL KPGLKDQPYA GSHSNMSEGS SRSSQEGLDC LQGDARQVVR RTQTSLGVAE
CRPHPPVTRV CSSPHGEAGR PRLLLSLNPV TPPHPHPDSQ SAASSAEDLP QGIRHQDIPS
PNSAHSGPPP PPYGGSSSRL SPAASKPAQP VSPSPAAPPH QHPLQGGRPM VPQNSASPTT
DSMVPMSQEW QDWQRDRWQI WQLLSSENAD TLPETLV
//
