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Database: UniProt
Entry: A0A1S3MVG2_SALSA
LinkDB: A0A1S3MVG2_SALSA
Original site: A0A1S3MVG2_SALSA 
ID   A0A1S3MVG2_SALSA        Unreviewed;       486 AA.
AC   A0A1S3MVG2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   08-MAY-2019, entry version 11.
DE   SubName: Full=gamma-aminobutyric acid receptor subunit alpha-5-like isoform X1 {ECO:0000313|RefSeq:XP_014007172.1};
GN   Name=LOC106575273 {ECO:0000313|RefSeq:XP_014007172.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014007172.1};
RN   [1] {ECO:0000313|RefSeq:XP_014007172.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014007172.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9)
CC       family. {ECO:0000256|RuleBase:RU000687,
CC       ECO:0000256|SAAS:SAAS00978283}.
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DR   RefSeq; XP_014007172.1; XM_014151697.1.
DR   GeneID; 106575273; -.
DR   KEGG; sasa:106575273; -.
DR   KO; K05175; -.
DR   OrthoDB; 1057372at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006028; GABAA/Glycine_rcpt.
DR   InterPro; IPR001390; GABAAa_rcpt.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   PRINTS; PR01079; GABAARALPHA.
DR   PRINTS; PR00253; GABAARECEPTR.
DR   PRINTS; PR00252; NRIONCHANNEL.
DR   SUPFAM; SSF63712; SSF63712; 1.
DR   SUPFAM; SSF90112; SSF90112; 1.
DR   TIGRFAMs; TIGR00860; LIC; 1.
DR   PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|SAAS:SAAS00457684};
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00766067};
KW   Ion channel {ECO:0000256|RuleBase:RU000687,
KW   ECO:0000256|SAAS:SAAS00081334};
KW   Ion transport {ECO:0000256|RuleBase:RU000687,
KW   ECO:0000256|SAAS:SAAS00457623};
KW   Membrane {ECO:0000256|SAAS:SAAS00978300, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_014007172.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00978734,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00978768,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU000687,
KW   ECO:0000256|SAAS:SAAS00457659}.
FT   TRANSMEM    279    303       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    344    367       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    453    471       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       57    278       Neur_chan_LBD. {ECO:0000259|Pfam:
FT                                PF02931}.
FT   DOMAIN      286    372       Neur_chan_memb. {ECO:0000259|Pfam:
FT                                PF02932}.
SQ   SEQUENCE   486 AA;  54734 MW;  85B1AAD0A91FACEB CRC64;
     MMALSTDIED RTPSFSTMKH VWISVLLVCI TCHVGLGQTT AEALKEAEAN DNITIFTRIL
     DGLLDGYDNR LRPGLGEKVT EIKTNIFVTS FGPVSDTEME YTIDVFFRQS WKDERLCFKG
     PMEMLPLNNL LASNIWTPDT FFLNGKKSIA HNMTTPNKLL RLKDDGTLLY TMRLTISAEC
     PMQLEDFPMD AHACPLKFGS CPPPSPSHRW PSGIHDAYPV SEVVYLWQTG AAHSVVVAED
     GSRLNQYHLI GQTAGSEDIY TSRGQYTVMM CHFYLKRKIG YFVIQTYMPC FMTVILSQVS
     FWLNRESVPA RTVFGVTTVL TMTTLSISAR NSLPKVAYAT AMDWFIAVCY AFVFSALIEF
     ATVNYFTKRS WAWDGKKAME AQHPKKRDPM VLSKKPNNVC TAGVNFTPNI TKDISISTIS
     NSTSIQLRSS ETEVLDPKKT YNSVSKIDKM SRIVFPVLFG TFNLVYWATY LNREPVIKGV
     NILAPT
//
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