ID A0A1S3N6L3_SALSA Unreviewed; 3629 AA.
AC A0A1S3N6L3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ankyrin-2-like isoform X4 {ECO:0000313|RefSeq:XP_014011042.1};
GN Name=LOC106577504 {ECO:0000313|RefSeq:XP_014011042.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014011042.1};
RN [1] {ECO:0000313|RefSeq:XP_014011042.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014011042.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR RefSeq; XP_014011042.1; XM_014155567.1.
DR OrthoDB; 5474900at2759; -.
DR Proteomes; UP000087266; Chromosome ssa18.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.220.30; -; 3.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24123:SF49; ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING 1B; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 3.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 3.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 23.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 21.
DR PROSITE; PS50088; ANK_REPEAT; 21.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 85..117
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 118..150
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..207
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 272..304
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 305..337
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 338..370
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 371..403
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 404..436
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 437..469
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 470..502
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 503..535
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 536..568
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 569..601
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 602..634
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 635..667
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 668..700
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 701..733
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 734..766
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 767..799
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 800..832
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1043..1231
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1233..1380
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 3172..3256
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 1531..1559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1761..2383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2396..2424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2459..2600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2612..2643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2664..2702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2730..2839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2864..3072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3287..3373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1539..1559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1773..1801
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1840..1856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1869..1885
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1886..1931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1932..1952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1959..1996
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1998..2029
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2049..2094
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2095..2111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2113..2148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2149..2178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2183..2215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2221..2235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2255..2274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2310..2341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2474..2498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2511..2528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2530..2552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2671..2695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2737..2751
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2761..2779
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2864..2885
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2887..2901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2924..2953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2963..2995
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2998..3014
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3316..3344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3345..3361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3629 AA; 397882 MW; FDABAADA5A05AF99 CRC64;
MGNAAMCKVC EAEKGLKANG SQPKMDHALP ESDYYCFEQH PEPEPEPQIL SDSNTSFLRA
ARAGNIDKVL EYLKGGVDIG TCNQNGLNAL HLAAKEGHVE LVQELLERGS AVDSATKKGN
TALHIASLAG QAEVVKILVK RGAEINSQSQ NGFTPLYMAA QENHMDVVRY LLENGGNQST
ATEDGFTPLA IALQQGHNQV VSVLLENDTK GKVRLPALHI AARKDDTKSA ALLLQNDHNA
DVQSKHCPLH GVCGICYCPQ MMVNRTTENG KSGFTPLHIA AHYGNVNVAT LLLNRGAAVD
FTARNGITPL HVASKRGNAN MVRLLLDRGS QIDAKTRDGL TPLHCAARSG HDPAVELLLE
RGAPMLARTK NGLSPLHMSA QGDHVECVKH LLQHKAPVDD VTLDYLTALH VAAHCGHYRV
TKLLLDKRAN PNARALNGFT PLHIACKKNR VKVMELLVKY GAFIQAITES GLTPIHVAAF
MGHLNIVLLL LQNGASPDVS NIRGETALHM AARAGQVEVV RCLLRNGALV DARAREDQTP
LHIASRLGKT EIVQLLLQHM AHPDASTTNG YTPLHISARE GQVDVASVLL EAGASHSLAT
KKGFTPLHVA SKYGSLDVTK LLLQKRAPPD SAGKNGLTPL HVAAHYDNQK VALLLLDKGA
SPHATAKNGY TPLHIAAKKN QMDIAVVLLQ YGAETNILTK QGVTPLHLAS QEGHADMAAL
LMEKGTQVNV PTKSGLTSLH LAAQEDKVAV GEILAKHGAN LDQQTKLGYT PLIVACHYGN
AKMVNFLLQN GASVNAKTKN GYTPLHQAAQ QGNTHIINLL LQNGAKPNNI TVNGNTALAI
ARRLGYISVV DTLKVVTEEI ITSTTTVTEK HKLNVPETMT EVLDVSDEEG LHTVPTVLKE
SEDDVLSDDS MDLEGDDTMT GDGGEYLRAE DLRELGDDSL PGQYMDGMNY LRFSLEGGRS
DSRLQSLDRS YTPSHHGYYS PKHESMIEEM LTSHNVSSLA REKEKDSYRL SWGTENLDNV
ALSSSPIHSG HSSPCHDHGD SSFLVSFMVD ARGGAMRGCR HNGLRIIIPP RKCSAPTRVT
CRLVKRHRLA TMPPMVEGEG LASRLIEVGP VGAQFLGKLH LPTAPPPLNE GESLVSRILQ
LGPPGTKFLG PVVVEIPHFA ALRGKERELV IMRSETGESW KEHHCEHTEE ELNQILNGMD
EELDPPEELE KKRICRIITR DFPQYFAVVS RVKQDSNLIG PEGGILSSTV VPTVQAVFPE
GALTKRIKVG LQAQPMNADV VKKLLGNKAT FSPIVTLEPR RRKFHKPITM TIPIPKSNTD
PVVNGFGGDQ PTLRLLCSIT GGTTPAQWED ITGTTPLTFI NDCVSFTTNV SARFWLIDCR
QVQESVSFST SVYREIICVP YMAKFVIFAK THDPIEARLR CFCMTDDKMD KTLEQQENFT
EVARSRDVEV LEGKPIYADC FGNLVPLTKS GQHHLFSFFA FKENRLALFI KIRDNTQDPC
GRLSFMKEPR SYRSLAHNAI CNLNITLPSY SKESDSDQEA EEEIGRKLEK YDEDTTSTET
TVRKRDLIRD STALASPDLL SDVSEMKQDL IKMTAILTTD STDKSSSMEG SGLEKGADEV
QGEPFEIMEK VKEDLEKVGK ILRSGTYEGE VAKEVARAAR MKEEWVLLSD CEIEEAKHMA
ALEPQEPILR EVRVNRGIPR PKAIKDVSGM VKHLSGELKE YLLDVPEGTS TTAQEKEVQE
KFTEVVLRKG AKITMTTTKT TTTTTTTKKD IKTPAFDLQK PVRRKGKDQQ QVEESTDGDV
HLSAPKHPQA VSPVSPVVEE TPIGSIKDKV KALQQKVEAE QKGQKPTSTK PSNVAVESKI
PQKAKETFPK QSPAKQGTAK QGPLKSPKTE SEKLEETMSV RELMRSFQKG QDPSKRKSGL
FELKTVSSEH ETTESESQPT QSKSTIKATS TCYEREVSLD AIPGKHHRER DKQINRPRKH
SKEFGAEIKA ELEDNPEYQQ FRQISVEGGP AAQSDLTETI EFPNSALDDS SDSLKHEGVA
DSPSASLGDF SPPHLSSEDS LKHQGFATPG TSPDSLSLSP KNADQSTKNS TAVTIAVEDD
KKSKDKSGDS GVGTIDDQPS NEITLPVSSS KAADDHITSE SISFQRVESK SSKPRKLTKR
VSETLESFLS DEESPDEKLA SALSATIASS ASTERQGSLE LPLRQQDSDA LSPLADDSLT
ISHRDSLDEG SPLMEDNSSH RTPDSIEPSP TKESPCRDSL ESSPVEQKNV PPAQPSGPSS
HPEPSKATDY PPDVLRSRLL RDQEASANDD DSIEQTLSQM ESSGKSPLSP DTPSSEEVSY
EVNPKTPDHM FLSVVSTPAV INEDSEEDDD ESEAQRKFTP EEEMFKMAAK IKTFEEMDQD
ARTKENSRKY ISASADDEAG DDSFKTVELE STNETELTGA KETSELALSV ESLIKVQPPS
PFPAGVHEGV QHTKAKSVAT TAAVEGTQSV SEQHVSQSVP SHKDTDDKDS LAQIATMSSS
SVGAANITDE QKEESLRNSR GSKEDDGGEK EADAGSLQTS VVKAPCQVES NITDEVKGDY
RGHPGAPEAE TSSTIIIGQA RETFKPEICI YDDTEEDDEE EEPPRTKSKG MTASEEADPW
SAMREDDDAF AARVKEEEQK ILGLMVDRHS QGETPDTTPG RSPTEESTPT SEPNPFLFQE
GKLFEMTRSG AIDMTKRTYE DEGFAFFQIG EQPLEEVLSE QVREEPGDRG APLESEVGLN
LTLEKKVEED EKQSKDAPED DQTGSGAIAA SPSKSDASKS RIPRMGLSAS AKTTKKDKDS
VSPVSPEALE VKPDTIVEET PLEVENSYLD PMIANVETAV TTVTRSVYPE QDQESSDSSP
EEQHSVIELP KTMEKTKTPT SSEKVKNIPN KTPAMAPAKA GPQSRATMYS SSTSPYSAIP
QKENPSTESK SRIPVKGKAS PVKPESSVKH TESSRDTKLK FPVKKDLRRK SETDACLSAV
PKTKTSSSKA KSFCEGDKTS AKKGQVRPMS ADYSTKPKSC FGFKSRLPVR GKLGQPSHTS
TPAKKKSEPR KKSIEFVNEI SDEAAKLVEG LAQVEKDKEH EVATAAISDD ESSGIDPSVI
ERETFPEMHF PTSGDVYPIR PLWDDPVDTQ MQRIPNDTIR RQVDPQDEAE RKEERLEIIA
DHLGFSWTEL ARELEFSEER INLIRIENPN SLQDQSHALL KLWTDRDGKH ATETTLIKRL
TKINRMDIVH LIETKIIKST QEDASSHTYA EIERTIALDH SEGFSALHED IDSPRPGRRT
DGTPSGPGSR QGPFMVSEED LSSSMSSLHE TSGQVETDTS VTGLLRHAQK EKLEKERETT
HSVGGTSQSG SEKAESLHMG TFKQADDLPD IPPQTVTEEQ YMDEHGNMVV KKITRKVIRK
YFSPDGVERE EVTVEGSHQE MVSVEEGDGF SKVVKRTVVR SEGDQTELTF SEPLALGATT
ASDFESEQVQ GRKVSKVVKT TVVRGERMEK QMGDSTLAAD LPSAKEDFEK ALSYAGGFGK
IQLPHLVEKE VVKDDGSVVK RTQMRKSRTQ KRTVVKDAQG KHVHLERLDD TPETLQPDAL
QQHLHLLLQR YCAKEEEEGE KEEEKRKKK
//
