ID A0A1S3N6W9_SALSA Unreviewed; 3596 AA.
AC A0A1S3N6W9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ankyrin-2-like isoform X16 {ECO:0000313|RefSeq:XP_014011055.1};
GN Name=LOC106577504 {ECO:0000313|RefSeq:XP_014011055.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014011055.1};
RN [1] {ECO:0000313|RefSeq:XP_014011055.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014011055.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR RefSeq; XP_014011055.1; XM_014155580.1.
DR OrthoDB; 5474900at2759; -.
DR Proteomes; UP000087266; Chromosome ssa18.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24123:SF49; ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING 1B; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 3.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 23.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 21.
DR PROSITE; PS50088; ANK_REPEAT; 21.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 85..117
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 118..150
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..207
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 272..304
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 305..337
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 338..370
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 371..403
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 404..436
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 437..469
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 470..502
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 503..535
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 536..568
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 569..601
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 602..634
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 635..667
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 668..700
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 701..733
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 734..766
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 767..799
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 800..832
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1043..1198
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1200..1347
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 3139..3223
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 1498..1526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1728..2313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2325..2349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2363..2391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2426..2567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2579..2610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2631..2668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2697..2806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2831..3039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3254..3340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1506..1526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1740..1768
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1807..1823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1836..1852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1853..1898
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1899..1919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1926..1963
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1965..1996
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2016..2061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2062..2078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2080..2115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2116..2145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2150..2182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2188..2202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2222..2241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2277..2308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2441..2465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2478..2495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2497..2519
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2638..2662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2704..2718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2728..2746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2831..2852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2854..2868
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2891..2920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2930..2962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2965..2981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3283..3311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3312..3328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3596 AA; 394422 MW; EB698B4EC36AE6EE CRC64;
MGNAAMCKVC EAEKGLKANG SQPKMDHALP ESDYYCFEQH PEPEPEPQIL SDSNTSFLRA
ARAGNIDKVL EYLKGGVDIG TCNQNGLNAL HLAAKEGHVE LVQELLERGS AVDSATKKGN
TALHIASLAG QAEVVKILVK RGAEINSQSQ NGFTPLYMAA QENHMDVVRY LLENGGNQST
ATEDGFTPLA IALQQGHNQV VSVLLENDTK GKVRLPALHI AARKDDTKSA ALLLQNDHNA
DVQSKHCPLH GVCGICYCPQ MMVNRTTENG KSGFTPLHIA AHYGNVNVAT LLLNRGAAVD
FTARNGITPL HVASKRGNAN MVRLLLDRGS QIDAKTRDGL TPLHCAARSG HDPAVELLLE
RGAPMLARTK NGLSPLHMSA QGDHVECVKH LLQHKAPVDD VTLDYLTALH VAAHCGHYRV
TKLLLDKRAN PNARALNGFT PLHIACKKNR VKVMELLVKY GAFIQAITES GLTPIHVAAF
MGHLNIVLLL LQNGASPDVS NIRGETALHM AARAGQVEVV RCLLRNGALV DARAREDQTP
LHIASRLGKT EIVQLLLQHM AHPDASTTNG YTPLHISARE GQVDVASVLL EAGASHSLAT
KKGFTPLHVA SKYGSLDVTK LLLQKRAPPD SAGKNGLTPL HVAAHYDNQK VALLLLDKGA
SPHATAKNGY TPLHIAAKKN QMDIAVVLLQ YGAETNILTK QGVTPLHLAS QEGHADMAAL
LMEKGTQVNV PTKSGLTSLH LAAQEDKVAV GEILAKHGAN LDQQTKLGYT PLIVACHYGN
AKMVNFLLQN GASVNAKTKN GYTPLHQAAQ QGNTHIINLL LQNGAKPNNI TVNGNTALAI
ARRLGYISVV DTLKVVTEEI ITSTTTVTEK HKLNVPETMT EVLDVSDEEG LHTVPTVLKE
SEDDVLSDDS MDLEGDDTMT GDGGEYLRAE DLRELGDDSL PGQYMDGMNY LRFSLEGGRS
DSRLQSLDRS YTPSHHGYYS PKHESMIEEM LTSHNVSSLA REKEKDSYRL SWGTENLDNV
ALSSSPIHSG HSSPCHDHGD SSFLVSFMVD ARGGAMRGCR HNGLRIIIPP RKCSAPTRVT
CRLVKRHRLA TMPPMVEGEG LASRLIEVGP VGAQFLGPVV VEIPHFAALR GKERELVIMR
SETGESWKEH HCEHTEEELN QILNGMDEEL DPPEELEKKR ICRIITRDFP QYFAVVSRVK
QDSNLIGPEG GILSSTVVPT VQAVFPEGAL TKRIKVGLQA QPMNADVVKK LLGNKATFSP
IVTLEPRRRK FHKPITMTIP IPKSNTDPVV NGFGGDQPTL RLLCSITGGT TPAQWEDITG
TTPLTFINDC VSFTTNVSAR FWLIDCRQVQ ESVSFSTSVY REIICVPYMA KFVIFAKTHD
PIEARLRCFC MTDDKMDKTL EQQENFTEVA RSRDVEVLEG KPIYADCFGN LVPLTKSGQH
HLFSFFAFKE NRLALFIKIR DNTQDPCGRL SFMKEPRSYR SLAHNAICNL NITLPSYSKE
SDSDQEAEEE IGRKLEKYDE DTTSTETTVR KRDLIRDSTA LASPDLLSDV SEMKQDLIKM
TAILTTDSTD KSSSMEGSGL EKGADEVQGE PFEIMEKVKE DLEKVGKILR SGTYEGEVAK
EVARAARMKE EWVLLSDCEI EEAKHMAALE PQEPILREVR VNRGIPRPKA IKDVSGMVKH
LSGELKEYLL DVPEGTSTTA QEKEVQEKFT EVVLRKGAKI TMTTTKTTTT TTTTKKDIKT
PAFDLQKPVR RKGKDQQQVE ESTDGDVHLS APKHPQAVSP VSPVVEETPI GSIKDKVKAL
QQKVEAEQKG QKPTSTKPSN VAVESKIPQK AKETFPKQSP AKQGTAKQGP LKSPKTESEK
LEETMSVREL MRSFQKGQDP SKRKSGLFEL KTVSSEHETT ESESQPTQSK STIKATSTCY
EREVSLDAIP GKHHRERDKQ INRPRKHSKE FGAEIKAELE DNPEYQQFRQ ISVEGGPAAQ
SDLTETIEFP NSALDDSSDS LKHEGVADSP SASLGDFSPP HLSSEDSLKH QGFATPGTSP
DSLSLSPKNA DQSTKNSTAV TIAVEDDKKS KDKSGDSGVG TIDDQPSNEI TLPVSSSKAA
DDHITSESIS FQRVESKSSK PRKLTKRVSE TLESFLSDEE SPDEKLASAL SATIASSAST
ERQGSLELPL RQQDSDALSP LADDSLTISH RDSLDEGSPL MEDNSSHRTP DSIEPSPTKE
SPCRDSLESS PVEQKNVPPA QPSGPSSHPE PSKATDYPPD VLRSRLLRDQ EASANDDDSI
EQTLSQMESS GKSPLSPDTP SSEEVSYEVN PKTPDHMFLS VVSTPAVINE DSEEDDDESE
AQRKFTPEEE MFKMAAKIKT FEEMDQDART KENSRKYISA SADDEAGDDS FKTVELESTN
ETELTGAKET SELALSVESL IKVQPPSPFP AGVHEGVQHT KAKSVATTAA VEGTQSVSEQ
HVSQSVPSHK DTDDKDSLAQ IATMSSSSVG AANITDEQKE ESLRNSRGSK EDDGGEKEAD
AGSLQTSVVK APCQVESNIT DEVKGDYRGH PGAPEAETSS TIIIGQARET FKPEICIYDD
TEEDDEEEEP PRTKSKGMTA SEEADPWSAM REDDDAFAAR VKEEEQKILG LMVDRHSQGE
TPDTTPGRSP TEESTPTSEP NPFLFQEGKL FEMTRSGAID MTKRTYEDEG FAFFQIGEQP
LEEVLSEQVR EEPGDRGAPL ESEVGLNLTL EKKVEEDEKQ SKDAPEDDQT GSGAIAASPS
KSDASKSRIP RMGLSASAKT TKKDKDSVSP VSPEALEVKP DTIVEETPLE VENSYLDPMI
ANVETAVTTV TRSVYPEQDQ ESSDSSPEEQ HSVIELPKTM EKTKTPTSSE KVKNIPNKTP
AMAPAKAGPQ SRATMYSSST SPYSAIPQKE NPSTESKSRI PVKGKASPVK PESSVKHTES
SRDTKLKFPV KKDLRRKSET DACLSAVPKT KTSSSKAKSF CEGDKTSAKK GQVRPMSADY
STKPKSCFGF KSRLPVRGKL GQPSHTSTPA KKKSEPRKKS IEFVNEISDE AAKLVEGLAQ
VEKDKEHEVA TAAISDDESS GIDPSVIERE TFPEMHFPTS GDVYPIRPLW DDPVDTQMQR
IPNDTIRRQV DPQDEAERKE ERLEIIADHL GFSWTELARE LEFSEERINL IRIENPNSLQ
DQSHALLKLW TDRDGKHATE TTLIKRLTKI NRMDIVHLIE TKIIKSTQED ASSHTYAEIE
RTIALDHSEG FSALHEDIDS PRPGRRTDGT PSGPGSRQGP FMVSEEDLSS SMSSLHETSG
QVETDTSVTG LLRHAQKEKL EKERETTHSV GGTSQSGSEK AESLHMGTFK QADDLPDIPP
QTVTEEQYMD EHGNMVVKKI TRKVIRKYFS PDGVEREEVT VEGSHQEMVS VEEGDGFSKV
VKRTVVRSEG DQTELTFSEP LALGATTASD FESEQVQGRK VSKVVKTTVV RGERMEKQMG
DSTLAADLPS AKEDFEKALS YAGGFGKIQL PHLVEKEVVK DDGSVVKRTQ MRKSRTQKRT
VVKDAQGKHV HLERLDDTPE TLQPDALQQH LHLLLQRYCA KEEEEGEKEE EKRKKK
//
