ID A0A1S3NCZ9_SALSA Unreviewed; 1125 AA.
AC A0A1S3NCZ9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=EMILIN-2-like isoform X1 {ECO:0000313|RefSeq:XP_014013277.1};
GN Name=LOC106578698 {ECO:0000313|RefSeq:XP_014013277.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014013277.1};
RN [1] {ECO:0000313|RefSeq:XP_014013277.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014013277.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR RefSeq; XP_014013277.1; XM_014157802.1.
DR AlphaFoldDB; A0A1S3NCZ9; -.
DR GeneID; 106578698; -.
DR KEGG; sasa:106578698; -.
DR OrthoDB; 5349070at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR PANTHER; PTHR15427:SF5; EMILIN-2; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF07546; EMI; 1.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..144
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 973..1124
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 145..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 740..767
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1125 AA; 122225 MW; 1648F2B2CFD210EB CRC64;
MFNICLLVVY FRCLKMKCLP TGFILKSALF PLLLTFPLIY GTRSRHNQGY NMFQGSAYSG
SEQRQRNKNW CAYVVHKNVS CAVVGGTESF VQPESAPCPK HQPICAQQVM YRTQFRPMYK
VGYKLVTELE WRCCPGHQGH DCKDLKGIPS SQTVLGPRPT LPPAPDHVPE TQDPGQQAWG
QSGHPWGAGR QPGGQTGQGP AGGQGGSQTT QQLEVVVQRL SQQILDMQAA MTSLSANLRV
DLQEDTSKML VTLLNVLRQP DSVRGEQQSM LLQGLSLEKE YNTVDIDKFT SKIKHLTDTI
NTKSNVLDDL QARVNHHDGQ LHLLMEASPV SPPPANDATL RAYVDTKFHT LKNEMMEGME
IKMADLKNSC DYKILSVQEQ CAGQENSYLS LTELLESKEM DLRKELQDFK NQLPNSQRGD
GTPPGVEELR KELFRVAEAQ LSLQSSLEKK SKPDPLLPRV EELEARLNMS ERSEEVRSLF
LEEKLRREGA EGAADLKKAM EDRMSSMEDR VTTLLVEISS PVCGAQTGLE ALQSAQALED
RLNSLEQLCS TECKSDQPAI ERIQQNLQVY RTSLDTMQSS INGHSASLGD MEEFVQGQLL
NHTASLTDVQ EELRALKGRM GGQEGSLSAM GLSLSQQSLE LQVQLLNHSA SLTGVEEALG
ALSGRMGVQK GSLSDLGVSL SANLKDVQEK LGALSGRMGE QEGSLSALGL SLSQQSLELH
QLNTCCLNSA GPDQEATDLL ELHLTQREEL RARLEELGQE VKAEADHCRN RTEGIALDVA
SMDSRVTSLE NVCGRLEPIS SSLHRIKEGL NKHVTGLWNC VSQINGTLQA HAKDIRGLKG
TYQNLQDHYS GITQALHHLT TRPENTGVHV GVEESGNPTE TKLVPQGPVL PVGPIPDGAL
AHMMETGEAG APGIIISSKP PKWADGSMST LKGFAGAPAS PPSTGSLKPN IPVISAVAHI
PLRLSLHKPY LTLTGERVSF SAGLNRLPFP GEVGIIRFNK VLVNDGGHYD PHTGIFNVPM
EGRYLLSAVL TAQRGARVEA VFSVSNRSIQ RLDTAGYLPD NGGGGGAGST SCDCGGSASL
SLVLTLMRGD RAGLVMTAGK LAISENTEVL STFSAVLLYP TPSKK
//
