ID   A0A1S3NFD2_SALSA        Unreviewed;       588 AA.
AC   A0A1S3NFD2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=MAGUK p55 subfamily member 3-like isoform X1 {ECO:0000313|RefSeq:XP_014014122.1};
GN   Name=LOC106579097 {ECO:0000313|RefSeq:XP_014014122.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014014122.1};
RN   [1] {ECO:0000313|RefSeq:XP_014014122.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014014122.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MAGUK family.
CC       {ECO:0000256|ARBA:ARBA00007014}.
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DR   RefSeq; XP_014014122.1; XM_014158647.1.
DR   AlphaFoldDB; A0A1S3NFD2; -.
DR   STRING; 8030.ENSSSAP00000087813; -.
DR   PaxDb; 8030-ENSSSAP00000087813; -.
DR   Ensembl; ENSSSAT00000121825; ENSSSAP00000087842; ENSSSAG00000069914.
DR   GeneID; 106579097; -.
DR   KEGG; sasa:106579097; -.
DR   CTD; 799884; -.
DR   OrthoDB; 2873706at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa19.
DR   Bgee; ENSSSAG00000069914; Expressed in brain and 2 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.10.287.650; L27 domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR014775; L27_C.
DR   InterPro; IPR004172; L27_dom.
DR   InterPro; IPR036892; L27_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR23122:SF47; MAGUK P55 SUBFAMILY MEMBER 3-LIKE ISOFORM X1; 1.
DR   PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF02828; L27; 2.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00569; L27; 2.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF101288; L27 domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS51022; L27; 2.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          10..64
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          65..122
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          141..222
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          230..300
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          387..571
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
SQ   SEQUENCE   588 AA;  66334 MW;  330BBA39B6213912 CRC64;
     MIEAMPHLSG STGLHETLAL LTSQLHPDAK HKEDLVFLKD VFSEKSLAYL MKIHEKLRQY
     ERQSPTPVLH SASCLAEDLA EEIQNGPMEG DERELLLLLS APHLKAILAA HDTVAQKNFD
     PVLPPLPDDV DDELEEESVK IVRLVKNKEP LGATIRRDEV TGAVIVARIM RGGAADRSGL
     VHVGDELREV NGNLIIHKRP DEISQILSQS QGSITLKIIP AVAEEDRLKE SKVYLKALFD
     YTPFEDKATP CQEAGLPFKR GDILQVVSQD DATWWQAKRV GDSNLRAALI PSTQFQERRL
     KYRIKMGTYQ APVSPKTPTY DLAERADCDS EGSQSGQDIA GLRRSFCLSR KYRQGSTGEP
     RTPDSAMLDF LIYEEVTRYQ PRPSERPRLV VLIGSLGARI NELKQTVIAE NPCHFGVAVP
     HTTRAKKSHE REGVEYNFIT KQAFEADIQS NIFIEYGEYK DNFYGTSLEA IRSVLDQNKI
     CLVDVQPEAL KILWTAEFKP YVIFVKPRIH ESHCKRHGSS SSLSVGITEE DLQEMRQSAV
     LMDERYGHLV DRVLVKEDLA SACVELRDIL QRVETEVHWV PICWVRTT
//