ID   A0A1S3NFK6_SALSA        Unreviewed;       715 AA.
AC   A0A1S3NFK6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Myosin light chain kinase, smooth muscle-like isoform X1 {ECO:0000313|RefSeq:XP_014014192.1};
GN   Name=LOC106579130 {ECO:0000313|RefSeq:XP_014014192.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014014192.1};
RN   [1] {ECO:0000313|RefSeq:XP_014014192.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014014192.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC       protein kinase family. {ECO:0000256|ARBA:ARBA00006692}.
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DR   RefSeq; XP_014014192.1; XM_014158717.1.
DR   AlphaFoldDB; A0A1S3NFK6; -.
DR   GeneID; 106579130; -.
DR   KEGG; sasa:106579130; -.
DR   OrthoDB; 4215065at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa19.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR47633; IMMUNOGLOBULIN; 1.
DR   PANTHER; PTHR47633:SF9; MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE-RELATED; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF07679; I-set; 2.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00060; FN3; 1.
DR   SMART; SM00409; IG; 2.
DR   SMART; SM00408; IGc2; 2.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 2.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50853; FN3; 1.
DR   PROSITE; PS50835; IG_LIKE; 2.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Kinase {ECO:0000313|RefSeq:XP_014014192.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000313|RefSeq:XP_014014192.1}.
FT   DOMAIN          68..160
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          168..268
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          291..546
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          625..712
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          38..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          589..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         320
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   715 AA;  79746 MW;  71271CE94BA32F6E CRC64;
     MDTGSMGPKK TFVSTFRMDF KPAAPQFVLK GIKNELEDRD TAQGGSRKQG TISTDITSKR
     RVSTEKGPLL EFLDPQEQLE VRVGGQARLH CAFRSCSVPV ASCWIYNREQ VVAGRPRTRV
     ESSDTDSSVE ISQACPDDAG TYTILVRNRR GLAQHTVTLS VIDRPHPPAS SPMVSQLSSC
     SLVLSWSGPS YDGGTAVTGY TVEVRREGTE KPEDWTEVTT HCKNTSYRIR SVLEPLGEYR
     FRVRAYNLAG VSEPSEVSDR VKMETRGELK EESQSYVTVT IDTTHKVKDH YNVHEKLGMG
     KFGQVFRLSH KETGQVCAGK FYRAHSSKAK AVARREIELM NCLHHPKLVQ CLGAYDTRSE
     IIMVMEYIAG GELFERIVDD NFEHTEPTSA RYMQQLLEGM QYIHRQNIVH LDLKPENIVC
     VDTTGTRIKI IDFGLAAKLE PGIPLMVMHG TPDFVAPEVI SYEPVGLATD MWSIGVICFI
     LLSGELPFQG NSDAETLSLV TAACYEFDQE SFEDISDQAK DFITSLLKKD TRCRLLCDEA
     LAHPWMASFT LLVRRPTKSL KKDKIRRFLA KRRWKTTGKA VLALQRMANL TNGPDSPGSP
     GEEASWSPAA EQAIQNLDQE LQSEPRFQQV LRDTSQPRGS TARLVCRVQG YPEPEVVWFK
     DEEPVESSSR VTVGYDGMCE LVLTDLGPAD SGVYKCRATN DLGEALCSAK LTVEL
//