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Database: UniProt
Entry: A0A1S3NG87_SALSA
LinkDB: A0A1S3NG87_SALSA
Original site: A0A1S3NG87_SALSA 
ID   A0A1S3NG87_SALSA        Unreviewed;       445 AA.
AC   A0A1S3NG87;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   11-DEC-2019, entry version 13.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 12-like {ECO:0000313|RefSeq:XP_014014463.1};
GN   Name=LOC106579252 {ECO:0000313|RefSeq:XP_014014463.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014014463.1};
RN   [1] {ECO:0000313|RefSeq:XP_014014463.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014014463.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR   RefSeq; XP_014014463.1; XM_014158988.1.
DR   GeneID; 106579252; -.
DR   KEGG; sasa:106579252; -.
DR   KO; K05005; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003272; K_chnl_inward-rec_Kir2.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR013673; K_chnl_inward-rec_Kir_N.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF14; PTHR11767:SF14; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   Pfam; PF08466; IRK_N; 1.
DR   PRINTS; PR01325; KIR22CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00434609,
KW   ECO:0000313|RefSeq:XP_014014463.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM        86..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..50
FT                   /note="IRK_N"
FT                   /evidence="ECO:0000259|Pfam:PF08466"
FT   DOMAIN          51..192
FT                   /note="IRK"
FT                   /evidence="ECO:0000259|Pfam:PF01007"
FT   DOMAIN          199..370
FT                   /note="IRK_C"
FT                   /evidence="ECO:0000259|Pfam:PF17655"
SQ   SEQUENCE   445 AA;  50511 MW;  7EB7B0898D938ADB CRC64;
     MSVGRLNRYS IVSSEEEALR LTNMHGGSSG GMNGFGNGKI HTRRKLRNRF VKKNGQCNVQ
     FANMEDKSSR YMADMFTTCV DIRWRYMLVL FTLVFVLSWL AFGLAFWVIA LLHGDLDNPA
     GDDNFTPCVL QVNGFVAAFL FSIETQSTIG YGYRCVTEEC PVAVFMVVFQ SIVGCIIDCF
     MIGAIMAKMA RPKKRAQTLL FSHNAVIAMR DSKLCLMWRV GNLRKSHIVE AHVRAQLIKP
     RITDEGEYIP LDQIDINVGF DKGLDRIFLV SPITIIHEID EDSPLYGIGK NDLETADFEI
     VVILEGMVEA TAMTTQARSS YLATEVLWGH RFEPVLFEEK NLYKVDYSHF HKTYEVPSTP
     RYSAKDMVEN KFLVPTSNSF CYENELAFLS RDEDEEEDVV GVGVGGGVRV LANLNSPDRT
     SRHEFERLQT TRGLDQRSYR RESEI
//
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