ID A0A1S3NH45_SALSA Unreviewed; 481 AA.
AC A0A1S3NH45;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Interferon regulatory factor 3 isoform X2 {ECO:0000313|RefSeq:XP_014014717.1};
GN Name=irf-3 {ECO:0000313|RefSeq:XP_014014717.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014014717.1};
RN [1] {ECO:0000313|RefSeq:XP_014014717.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014014717.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014014717.1; XM_014159242.1.
DR AlphaFoldDB; A0A1S3NH45; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF1; INTERFERON REGULATORY FACTOR 3; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 5..106
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 481 AA; 53786 MW; 403A07AB13D6543A CRC64;
MSQSKPLLIP WLREQINSGQ YPGVTWTNQE RTEFCIPWKH ALRQDSCSDD VLIFKAWAEV
SNGRVQGDPS IWKRNFRSAL RAKGFKMLLD NKNDAANPNK LFQWPDEAPT GGSQHPEHDL
YQDPSPLQES DGLPCLNDLY HAAEETVYTE GISTTFNQDI LQKCLQGLNI EQTAGNQPFQ
CGTLDQGSPT EAIQGYELTV EQRQYPMEGA IGGHVLQGQQ QYPVVMEDAV GGAVLPPQPV
YPMDGPVGGA HEQQVVEQFT NELSRTMVGE NFKTHFRVSV YYRGLKMLEQ LVENEAGFRL
VYRPELTQPL LDPDSGLNLV SLPSPPPVRD ETQAKLTQDI LALLGEGLEV GASGPIIYGL
RKGGIKAFWS LDKFDKSRRP QAVSKFPEPL YQAKDFYGGL LKFMDSHRGE CPPFSLFFCL
GEKWPDPDNR PWEKKLVMVE VVLTALELLK SIAVEGGASS LQSVELQLSL QESLQEMMDL
C
//
