ID   A0A1S3NHA3_SALSA        Unreviewed;       748 AA.
AC   A0A1S3NHA3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Rho GTPase-activating protein 44-like isoform X3 {ECO:0000313|RefSeq:XP_014014561.1};
GN   Name=LOC106579296 {ECO:0000313|RefSeq:XP_014014561.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014014561.1};
RN   [1] {ECO:0000313|RefSeq:XP_014014561.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014014561.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014014561.1; XM_014159086.1.
DR   AlphaFoldDB; A0A1S3NHA3; -.
DR   GeneID; 106579296; -.
DR   OrthoDB; 7959at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa19.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR   PANTHER; PTHR14130:SF13; RHO GTPASE-ACTIVATING PROTEIN 44; 1.
DR   Pfam; PF03114; BAR; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00721; BAR; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51021; BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          14..252
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   DOMAIN          258..448
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          467..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          529..748
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          140..203
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        479..493
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        529..549
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        634..648
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        656..704
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        706..724
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   748 AA;  82098 MW;  39C5B23B6EF64E66 CRC64;
     MKKQFNRMRQ LANQTVGRAE KTEVLSEDLL QVEKRLELVK QVSHSTHKKL TACLQGQQGV
     DVEKRSVRSP SKKLPLTTLA QCLVEGAAVL GDDSLLGKML KLCGETQEKM AQELILFEFT
     IDRDVVEPLY ELAEVEIPNI QKQRKQLAKL VLDMDSARTR FHQSSKSGMS SNVQPGAKGE
     HLREEMEEAA NRMEICRDQL SADMYNFVAK EIDYASYFQA LIEVQAQYHR KSLELLQNIL
     PQIKAHQETW VEKPCYGKPL EEHLALSGRD IAFPIEACVT MLLECGMQEE GLFRVAPSAS
     KLKKLKASLD CGVMDVQEYS IDPHAIAGAL KSYLRELPEP LMTFELYDEW IQASNIQDQD
     KRLQALLTAC KKLPLANGNN FKYLIKFLAK LDDYQDENKM TPGNIAIVLG PNLLWTTQEG
     NITEMMTTVS LQIVGIIEPI IQHADWFFPG EIEFNVTGNY GSPVHTNHNA NYSSMPSPDM
     DHSDRKHNDQ SRRPLSVATD NMMLEFYKKD GSVRKIQSMG VRVMDTSWVS RRGSSSARKS
     SSTPLGVQSP LLPSDALIPE QGEVSASPSP TPPPASSDRA STLKNNELSP VIGQKGFQGT
     APSGGLSQHS SEHSPHTLRR AKKLAPIPPK PYSQSGGMSD QSTGQPSPVS LSPTPPSTPS
     LYGFSYPQGY ATIGSPGQAQ TATPSLSSPP SLAGTLTKAR PTSKPPRQRP SLPPPQPPST
     PGSSPQPLEH GGGLLDGLSP GESMSTAV
//