ID A0A1S3NI57_SALSA Unreviewed; 4978 AA.
AC A0A1S3NI57;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=[histone H3]-lysine(4) N-methyltransferase {ECO:0000256|ARBA:ARBA00023620};
DE EC=2.1.1.364 {ECO:0000256|ARBA:ARBA00023620};
GN Name=LOC106579599 {ECO:0000313|RefSeq:XP_014015134.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014015134.1};
RN [1] {ECO:0000313|RefSeq:XP_014015134.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014015134.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = H(+) +
CC N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:60264, Rhea:RHEA-COMP:15543, Rhea:RHEA-COMP:15547,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:61929; EC=2.1.1.364;
CC Evidence={ECO:0000256|ARBA:ARBA00024515};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60265;
CC Evidence={ECO:0000256|ARBA:ARBA00024515};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014015134.1; XM_014159659.1.
DR GeneID; 106579599; -.
DR OrthoDB; 4253584at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0140999; F:histone H3K4 trimethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd22026; HMG-box_KMT2C; 1.
DR CDD; cd15513; PHD5_KMT2C_like; 1.
DR CDD; cd19171; SET_KMT2C_2D; 1.
DR Gene3D; 3.30.160.360; -; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003889; FYrich_C.
DR InterPro; IPR003888; FYrich_N.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888:SF1; HISTONE-LYSINE N-METHYLTRANSFERASE 2C; 1.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR Pfam; PF05965; FYRC; 1.
DR Pfam; PF05964; FYRN; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00542; FYRC; 1.
DR SMART; SM00541; FYRN; 1.
DR SMART; SM00249; PHD; 4.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS51543; FYRC; 1.
DR PROSITE; PS51542; FYRN; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS50016; ZF_PHD_2; 3.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 752..805
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 802..852
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 879..934
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 4447..4555
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 4838..4954
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 4962..4978
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 71..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1052..1142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1218..1238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1380..1406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1474..1504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1645..1698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1710..1941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1967..2427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2644..2691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2766..2820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2987..3015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3177..3200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3282..3407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3433..3532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3545..3701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3726..3883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4077..4101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4203..4242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4342..4363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3205..3242
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 125..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1404
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1667..1698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1710..1762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1797..1832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1852..1866
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1892..1906
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1916..1931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2073..2088
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2089..2103
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2139..2157
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2158..2188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2280..2311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2325..2353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2368..2386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2667..2682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2766..2794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2987..3011
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3313..3355
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3361..3384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3389..3407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3466..3502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3580..3596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3622..3657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3675..3701
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3779..3837
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3853..3879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4203..4234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4978 AA; 544012 MW; EE7EFBEBDDB14BE4 CRC64;
MAVVEVVVPL EREACPGPRL EREACPGPRL EREACPGPRL EREACPGPRL EREACPGPRL
EREACPGPRL EREACPGPEQ EACPLKEGEA CPSPQQEEGT CPRREDGACP IKEGAACPSP
RREEGACPSP RREEGACPSP RREEGACPSP RREEVACPSP RREEGACPSP RREEGACPSP
RREEGACPSP RREEGACPSP RREEGACPSP RREEGACPSP RREEGACPSP QQEEGMCPRR
EDGACPIKEG AACPSPRREE GACPSPRREE GACPSPRREE GACPRREEGA CPRREEGACP
RREEGACPSP LKEQEPKESP SGAEPAQEIQ VTVTLTEGPE SPQRSGTLVG MSPLASQSPA
APRAVDDQQE LEISDSPEAA KRAAPEEALP HNAGQTKSED SKTTFTPPTK EISHEPLEEI
TEEPPVEEEK PMEVVPVEMT PSDLEQAVEE KFLEPMQEEQ GAVAEKEVVQ KLQKELEGED
LPPIVLDEGE VLPSNVLPVE EDTIREKEPS PMAELPQRKS TVEMDTTPAS DCSFSDFGSP
RGESKAPKAS PGMSPELSFR LAPSPFSTEA SPRKASPPQV QVQIQAQASP QVQPYPGYSA
SVLPTNTTFI PLTPKIGMGK PAISKRKFSP GRPRVKQGAW SNRRAASPPS WSQQDPSEGG
WDGPQTRQLQ EAPVWSMRVG RGSTFPGRRR PRGANLSGRG GRGRSRGLKA YTSFAVTPGA
SFVEQPYLVV EENTMHNTVV MFSTSDHFTL RQDMCVVCGS FGQGAEGRLL ACSQCGQCYH
PFCVNIKITR VVLSKGWRCL ECTVCEACGQ ASDPGRLLLC DDCDISYHTY CLDPPLQTVP
KGSWKCKWCV SCTQCGATSP GLRCDWQNHY TLCGPCGSLA SCPVCMRSYR EDELIVQCRQ
CDRWVHACCQ GLNTDEEVEN AADDGFDCTM CRMHALPSQG KMKALLSDGC EAPMVTQMVT
KTREPANQKT YTQDGVCLTE SGMCQLQSLV VPSSSTRRGQ NRRPKPKLKL KIINQNSVAV
LQSPLDPHYL ELSRDGYMDN NRGDLMMYCD VKSESSPERE PVDDDAKGAE DTDGNKKRKR
KPYRPGIGGF MVRQRSRTGQ GIAKRSLSRK ASTWSLPENP MCKEEGWNET ESTPVEETPP
VPECQEKVKK RYRKKKTKLE EEFPSYLQEA FFGKGLLDKS KQSRQAGLVT TGLCEQLLDK
CKQSSQTGLV TMGLCEESPG AHAETKPPSA SFLDPLSDPL LSATSTTTPI SSKAGLPNTE
DPLVDLSEVL STDADLLGML SDDLVKSGHN SGLDLCPFQV DCSSSPFAGL DMDPIPDDPT
GPCQGSACRG PRALPEEPLD VILSPELDKM VADGAILSKL YKIPELEGKD VEDLFTAVLS
PSTSQPPQLP HPQPAHPGPN GPRAMAIPNP GNHGMFPRMP MMNGMMRPNP HFPPTPMMPG
STGPCGLGNF SPIHRMPFPD KIRDKKFSQM GGDVVGSWSA PSSDPGPVPG PVPPPEGETD
TMSNAQRSTL KWEKEETLGE MATVAPVLYT NVNFPNLLEE FPDWAMRVKQ IAKLWRKASS
QDRAPYVQKA RDNRAALRIN KVQMSNDTLK RHQHPQQQQP LLTDTFDPNS VPLDTELLFK
DSLKPKESEH EQEWKFRQGE LNQMWGPLKK QQEKVPKSKA IKSTNKDVLF GHSNQATIAA
GGGKNSLQMR QKSKQQAKIE ATQKLEQVKN EQLQQQQQQQ QQQLFSSQSG GDTTPNSGNQ
SPMTPQPSNG GKSGNSSPLQ PIASKDGFAR PQLPGTPTSG SQDDVFLRPQ LPPPSSRTPT
QETSYPQQGP SSQPQSPHMF SPGSSSGSRP SSPWDPYAKM VGTPRPPHGG GGSTTPRQNS
LSEMQERGGR PSPAHESFVL PTSGNADPYA KMPDTPRPPD PFVKPMGPAR VVPSGLVEQQ
QHQQVRHNMM SPPSGGETFA RMGGHRDEVY QRMSHNRMIL SDPYSRPLLT PIPGSNESGS
VPVFKAPMPP QQSQQEPYSG PMPGGLKRGP SDGFPQGLQA DPYAQQPLTP RPPMGEGFPN
EPKMMRQTQE GHFSQPLPMI RHPHRNLYAQ APSTPRPDYS QQMSDPYAQP PGTPRPHSDS
YAQPPGTPRP HSDSYAQPPG TPRPHSDSYA QPPGTPRPHS DSYAQPPGTP RPHSDPSYLQ
TPPNLRLDQF PQQHPPNHRQ SPSHSMDPYA SMPGTPRPAP GDRFPKSPGS QRNMDPYAQQ
PGTPRPLLTD PYAQAPGTSR PEAGPDAFNR LCSRPTPMSQ VPADPFSHQS PGRVQDGFAC
PSAQGSQTAK HPGMSDESFS LPQSNHHGGQ TQIHDPFELG PMTPYAQTSE RQAHDIPQSS
SNTVDTQNSM LPHLGDTEEK LRQRQRLRQQ ILRQQQQKSA IQQEKGLLQE TVAAPSPGTP
RHWSHEDSAP QNDMFGRPPP PYPGPMRGGQ RFPGTFLGDQ RGHFPNEGQF ARPHFPRDMG
NMGMRPQEIR FGFPPSAQGS LQPGQEQHFL RPLHQMPGGP IVDNVPPQMR MSHSVDFSRG
VMGGNTQMGL PQPFPPQGLS VQQHNIMGQP FIELRHRAPQ NRMRIPFGHG PPNVMDPSNQ
PQIPPQGFME GQEMGFAGNQ GSRMMDPMMD RPSQGSVGHT HTSASMENLH QQQTEVPMTM
GQRQHPSLNR SLSHPVTGEP LNAAPSSMLL PGSSTGQTEE TPIPSGDGIE ENMDAEDSAV
KDLEDVEVKD LVDLNLNLDP DDGKDLELGP NDLHLDDFLM SGKFDLIAYT DPELNLDDKK
DMFSEEDLDL GDPMEDHQQG ETSDLQKALS EKRKGSMDGA ATSSRSGGKS DKREAIEAKE
TLDMFKTEDT IKTEVKDEHV QNQDQSLCSG PMNDNRTMTN QEGAGLYEQP GQTDSSSTPV
LSCLLIKEKL ENTGFGPNCS PHQGDMAAQA TGLHASTSML MLPRQHAQDN NRFNPSVAMG
HRVSPTLVQS RHSMGKLISG GNHSFGASAN QQVEMNLAMV VAGQQPTAHG LNPQGQQGMF
PQQQGPSLGQ AGPQNRPLLL EEQPLLLQDL LDQERQEQQQ QRQMQAMIRQ RSSDSFFPNM
ADFDAITDPI MKAKMVALKG INKVMAQNSM GMPPIVINRI QQTPGAHGPD AAAALPQHVL
GQDGKLAPQM ARPNPPNFGP GFVNDSQRKQ YEEWLQETQQ LLQMQQKFLE DQIGAHRKSK
KALSAKQRTA KKAGREFPEE DVEQLKHVTE QQSVVQKQLE QIRKQQKDHA ELIEEYRVKQ
QQQRPSLQAP MMPGMPTQAA PMMPGAPPMG QPMMGPMMPM QPHPGQHNPA RIPNMPGWHP
GGAQGLMGGP GPRIPAHMPP PMPLASPAQL PQLPPPQLAP QAQLPPQPPP SVVPGAKATP
TGNGTGAQGA SGGSGGNSLA VKFDDNNPFS EGFQERERRD RLREQQERQR VQLMQEVERH
RAMQQRLEME QQGLGLGPTG LPSGPGATNP GGDSLAHMPF YSTDLPQDFM QPSRPQQQQG
QLGPMYPEQS NMQPSFTSTG GPLPGQGFMP DGERRSMPGN RAFGSPEMGP NFRSKIPMLQ
GLNYPPGQPR PTGFRGRGMM PQVGGEGHGP PFGMDSSTPL PPNYPGSGQS LIQLYSNIIP
EEKAKKKRNR KKKRDSVDDA DSVKTPSTPH SDHCTPLTPS HVSDTSSTPT RSLSIPGEQD
LSDLFLPVGS SGLAPSSELE RQLSGSSLAQ GGLSNMGSEN DRASLFDETL QIKLERIETE
CRGAAAANEG SALGHGPRAG GVVKEEGSEG GLSSPVHGAK GGDAGNELLK HLLKNKSTPP
PCASANQTPP TQQMSCNSLS SEQEASAALK ATAKPASTTN NMTPPHSQLT GSTELLEPSV
PAQGKRKQQR NKRTPKNGAE KPPSRYKRRK KEEEERQIGY SSTDSLTQLK QQLSLLPLME
PLMGVNFAHF PPFGSGQLNG ENRLSGSFGS ASLDGVSDYY SQLIYKQNNL SNPPTPPASL
PPTPPPMARQ KMVNGFATAD DLARKAAVLG GHDVIKGLGA KHLPTAFRTE EDLMAHAITQ
GPKTVDVPAS LPTPPHNNQE ELRGQDHCVD RDTPDSFVPS SSPESVVGME ISRYPDLSKV
KEEPTSPCSS PVIPMLPSAS GKGTEIKQEV KTEPSSSFFG SQFGQPPSCT KAGLVSIEIT
LNPVSAENIP GVVAAVAELL CVTVPSSYEV TRSPERSSLA LLAGLKVPQT QGMDPLHVSM
FPQHQQPPTM RSLRPPGSPN QPRISQQFQP IGPPTSAGSA ARGEGPKPQW CCHCKVVVLG
NGVRKSTKDL ACSKRERPSL VFCSRNCFVL HAAATQSKAT DSKPNISPLL PESSVKESPS
KVLHKYSNNM STLDVRCLAK LQPKESAPSS PPPISFPTEK PKPDTLKVTV KLKPRPRAVH
SASGGGDDMS PRHHKRWKGL RWRKWSVHVV FPTRGSLLSS LPGEDEVDEL LRKLGASLRP
DPLPRDLRRC CFCHEEGDGM TDGPARLLNL DLDLWVHLNC ALWSSEVYET QAGALINVEL
ALRRGMAVRC TYCQQTGATS GCHRLRCGNA YHFTCALKAQ CTFFKDKTML CHLHRPRGIG
SGGDRAVAPA TPHHDQELRC FTVFRRVYVQ RDEARQMASI VQRGERRHTF RVGSLVFHTV
GQLLPQQMAA FHSANAIFPV GYRASRIYWS TRHGNHRCRY LCSVEENEGQ PEFVVRVIEQ
GYDDLVLTGA SPKGVWDKIL EPVADRRNES GTLKLFPVYL KGEDLFGFTV TAVTRIVESL
PGVEACDRYT FRFGRNPLME LPLAINPSGS ARSEPKACSH VKRLVLRPHT LSSTGIVSSK
SMQTVGSVGV VEAPEEVIPK QFASVPFQYR RMKAEWKSNV YLARSRIQGL GLYAARDIES
HTMVIEYIGT LIRNEVANRM EKMYESQNRG VYMFRLDSEH VVDATITGGP ARYINHSCAP
NCIAEAVSLE RGDKIVISSC RNIQRGEELC YDYKFDLEDD QHKIPCHCGA VNCRKWMN
//
