ID A0A1S3NIR1_SALSA Unreviewed; 380 AA.
AC A0A1S3NIR1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Serpin B6 {ECO:0000256|ARBA:ARBA00039202};
GN Name=LOC106579695 {ECO:0000313|RefSeq:XP_014015303.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014015303.1};
RN [1] {ECO:0000313|RefSeq:XP_014015303.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014015303.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Forms a complex with the monomeric form of beta-tryptase.
CC {ECO:0000256|ARBA:ARBA00038828}.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014015303.1; XM_014159828.1.
DR AlphaFoldDB; A0A1S3NIR1; -.
DR STRING; 8030.ENSSSAP00000012666; -.
DR PaxDb; 8030-ENSSSAP00000012666; -.
DR GeneID; 106579695; -.
DR KEGG; sasa:106579695; -.
DR OMA; TPMFVAD; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR Bgee; ENSSSAG00000006314; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19956; serpinB; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF204; SERPIN B6; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..380
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 380 AA; 42711 MW; 2F3BEB7F7A36B63D CRC64;
MAAVSVANGN FTLALFKKIT EKNKTGNVLY SPLSISAALA MVLLGARANT ATQLSETMCF
NKATDDIHVG FGKLIHDLNQ QGAPYSLSLA NRLYGEQSYQ FVETFLCDTK KHYNVELEAV
DFKSNAETCR KNINAWVEKQ TSEKIKDLLP EEVVDHLTRL VLVDAVYFKG NWFKQFKEAD
TSDAQFKLNK NESKPVKMMH QTAKFPLTFI PEANCQILCL QYEGNELSMF IMLPNDMEDH
VTGLVKLEKL LTYEKIVQWT RPDMMAAVEV QVGLPKFKLE EILDLKDLLI SMGMTDAFDL
AKADFSGMSP SNDLVLSEVV HKAFVEVNEE GTEAAGAMAP IMGMRCTLRT PMFVADHPFL
FFISHNTTES ILFYGRYCSP
//
