ID A0A1S3NJ84_SALSA Unreviewed; 628 AA.
AC A0A1S3NJ84;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Rho GTPase-activating protein 18-like isoform X3 {ECO:0000313|RefSeq:XP_014015256.1};
GN Name=LOC106579655 {ECO:0000313|RefSeq:XP_014015256.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014015256.1};
RN [1] {ECO:0000313|RefSeq:XP_014015256.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014015256.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014015256.1; XM_014159781.1.
DR AlphaFoldDB; A0A1S3NJ84; -.
DR GeneID; 106579655; -.
DR OrthoDB; 11483at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04391; RhoGAP_ARHGAP18; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR PANTHER; PTHR14963:SF5; RHO GTPASE-ACTIVATING PROTEIN 28; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 289..485
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..146
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 71026 MW; 5F2A1CB23BD0400B CRC64;
MSSTGTRPSS PPSPPERPAS RDSQDSQDSM EDYWSEVKNI EEDGQRGHED LLERGSMDEA
ELEEAWLQDA GLSTLVSGAL GEGPAEALLS TLTRSQAAMV KKRVDNYTLT VRKRSKQPTR
HVRDVFSTPD TSPVDPIPPV PPKSPNGDVP SRCVHRTSSR VRPACPSFSQ STERRVSECP
PCPPPQDTSD SLSFEVPYSE GITAHRRGRQ GDCKDCQRIR RDDHDLPMFQ LPRPKLGLTR
IQDLSCEDMK KIGYISLIEL TTFYDGLGIE LKRNRAARSK ARESGIFGVP LTTLLENDQK
KFPGSKVPLV FRKLLSKLEQ TGLQTEGILR VPGSASRVKH LRQELEQKLY EDRFDWEQVR
HNDAAGLLKM FIRELPYPLL TLQHAPAFAA AQNISSPRQQ IQALHLLIML LPEPNRDTLK
ALLEFLRKVV AYEEKNRMGL WNVSMIVAPN LFTYRGKNAK QEEMQGAAGA AHLVRLLITH
QDLLWTVPCF LISHVRKLNE AGASKKPPSS EKTKRKLLLM RRKTTEREKT ERSELTDLRQ
GVIRVHAPQH AKISMAIQLD NETKAKDVMA RFDYENGRGT RSTSRRPRQY LFEVGGNIGE
RSLDPETHLL DVYHVNPHCE WVLKPTTT
//
