ID A0A1S3NK09_SALSA Unreviewed; 648 AA.
AC A0A1S3NK09;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Macoilin-2-like isoform X2 {ECO:0000313|RefSeq:XP_014015595.1};
GN Name=LOC106579821 {ECO:0000313|RefSeq:XP_014015595.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014015595.1};
RN [1] {ECO:0000313|RefSeq:XP_014015595.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014015595.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Nucleus membrane
CC {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004232}. Rough endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004269}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004269}.
CC -!- SIMILARITY: Belongs to the macoilin family.
CC {ECO:0000256|ARBA:ARBA00008298}.
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DR RefSeq; XP_014015595.1; XM_014160120.1.
DR AlphaFoldDB; A0A1S3NK09; -.
DR OrthoDB; 2882564at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030867; C:rough endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0023041; P:neuronal signal transduction; IEA:InterPro.
DR InterPro; IPR019130; Macoilin.
DR PANTHER; PTHR47464; MACOILIN; 1.
DR PANTHER; PTHR47464:SF3; MACOILIN-2 ISOFORM X1; 1.
DR Pfam; PF09726; Macoilin; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 197..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 367..535
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 648 AA; 73619 MW; 6D33260DD51C8AFB CRC64;
MARLSHTFLY LKFLVVWALV LLADFVLEFR FEYLWPFWLF IRSVYDSFRY QGLAFSVFFV
CVAFTSDTIC LLFIPVQWLF FAASTYVWVQ YVWHTERGVC LPTVSLWILF VYIEAAIRFK
DLKNFHVDLC RPFASHCIGY PVVTLGFGFN SYVSYKMRLR RQEVVQKENE FYMQLLLQAL
PPEQQMLQRQ EREAEEAALA KGISEMDSTP VSQNGAPASK KMSAMLPELE YREKGKEGRE
AKKQHNSILP SSVDSKLQEI EYMENHMNNK RLTTELVGST ENLLLKEENS SSSSSSKNYK
NSSGNAAVNS LPCGHCATNG CVQSAPSSFS WGKKQKCAAG KGPAVGSHRD PTDNCIPNNH
LSKPEALVRL EQDVKKLKAD LQASRQVEQD LRSQIGSLGS AERSIRSELG QLRQENELLQ
NKLHNTIQAK QKDKQAMGQL EKRLKVEQEA RANVEKQLAD EKKRKKLEDA TAARAVVLAA
ASRGECTDTM RRRITELETE CKKLTMDINL KEDQLRELEM TVQELHKYKE NEKDTEVLMS
ALSAMQEKTQ HLENSLSAET RIKLDLFSAL GDAKRQLEIA QGQIPQKDQE IKDLKQKIAE
VMAVMPSISY TAESSNMTPV APHYSSKFMD TSPSGLDPNA SIYQPLKK
//
