ID   A0A1S3NKL0_SALSA        Unreviewed;      1087 AA.
AC   A0A1S3NKL0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Transmembrane protein 132C-like isoform X2 {ECO:0000313|RefSeq:XP_014015736.1};
GN   Name=LOC106579906 {ECO:0000313|RefSeq:XP_014015736.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014015736.1};
RN   [1] {ECO:0000313|RefSeq:XP_014015736.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014015736.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the TMEM132 family.
CC       {ECO:0000256|ARBA:ARBA00006166}.
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DR   RefSeq; XP_014015736.1; XM_014160261.1.
DR   AlphaFoldDB; A0A1S3NKL0; -.
DR   GeneID; 106579906; -.
DR   OrthoDB; 3670111at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa20.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026307; TMEM132.
DR   InterPro; IPR031436; TMEM132_C.
DR   InterPro; IPR031437; TMEM132_M.
DR   InterPro; IPR031435; TMEM132_N.
DR   PANTHER; PTHR13388:SF4; TRANSMEMBRANE PROTEIN 132C; 1.
DR   PANTHER; PTHR13388; UNCHARACTERIZED; 1.
DR   Pfam; PF16070; TMEM132; 1.
DR   Pfam; PF15706; TMEM132D_C; 1.
DR   Pfam; PF15705; TMEM132D_N; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..1087
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010222853"
FT   TRANSMEM        903..928
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          36..164
FT                   /note="Transmembrane protein TMEM132 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15705"
FT   DOMAIN          424..768
FT                   /note="Transmembrane protein family 132 middle"
FT                   /evidence="ECO:0000259|Pfam:PF16070"
FT   DOMAIN          875..956
FT                   /note="Transmembrane protein TMEM132 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15706"
FT   REGION          227..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          786..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1005..1026
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        800..816
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1008..1026
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1087 AA;  121104 MW;  9DB2321F64DC1486 CRC64;
     MLHLRALQSI MVLLGADCRV LEGLQRFSSI PTYLPVNYQV INAESAFFLK EANQEFMRNS
     SLLSRTEPFF IYQARSMPSV NASYGPLSVE QPVTLELIQN PWAFVASSMF TFNWKVQTFI
     IQDRIYRSNP RVQVLFYVAG RDWDDYSAID KLPCVRMFAF HETQEVRGTC QLKGELGLCV
     AELEPLAGWF SPPSVVPGRQ RTIELAEGTT VELYYMLQST EAGACHSEEA RKGNSIRSDQ
     EGLFGSSTST PMKRIGSVRL YQSPAALALT EHRLDSNFLV MVPTTPMRQR DTVSAFITAS
     AFSPVEMFTL RVKLKEGMAF LGARPSNPTL WMVSQDVRSE GHRVVTLHCR RKESSYGQRS
     EEGVQRVLQV DLEVDSFLGP LGSRWITWQV EYPGSRATTQ EAETEIRLAQ KDLGGIVPLA
     MDTEILNTAV LTGKTVAVPV KVVTIGADGM VTDVSEAVDC HSTDEDVVKV SDRCDYVFVN
     GKEMKGKVRM MVNFTYSYLS AQLEMNVWIP RLPLQIEVSD TELSQIKGWR VPIMTSSQRS
     ALDSDDEDDE DRRGRSCTLQ YQNAMVRVLT HFVAEAADPR GQLTFMLGSD WQADITGLVW
     DFLKVEDPQI AQLQDRRILV GLDMGMTTIQ VLSPLSDSIL AEKTVTVVNN KVTITELGVQ
     LVTGLALNLQ LSPGSNKAIL ATATTQEVLQ SPKQEALISA WLHFSDGSMA PLDLYNSDYF
     VLTATSLDEE VVTVQQDPSW KWPVIVTEAE GQGLLVRVEM TVCELCQKFK RRSVLAAGNC
     NVKVKFGQSD GGTSRNSDYG PEGEELENRA SDRRQQSPSQ DRTGLEAHYY GSSISDMEDG
     VMRKVTTTTK STIIRRLNGD KLSDDGNQVQ NMPDFPAQVD LPRSHNMEDD LIQTARGLTD
     LEIGMYALLG VFCLAILVFL INCISYTLKY RHKELSIEGQ ESMNHAHDWV WLGNEAELLE
     SHMSLSPQQD ELTSMVDCSA GLEEGSHLLN GASSQKNVQG QVHRAADRAS CTAKDSKGDS
     PTTKRKRVKF TTFTTIPPDN GCPTVSTLSM SHSQDIKWVC QDVELGDSKE LRNYMERLND
     SALKEVA
//