ID   A0A1S3NPI7_SALSA        Unreviewed;      1608 AA.
AC   A0A1S3NPI7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Rapamycin-insensitive companion of mTOR-like isoform X6 {ECO:0000313|RefSeq:XP_014017289.1};
GN   Name=LOC106580589 {ECO:0000313|RefSeq:XP_014017289.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014017289.1};
RN   [1] {ECO:0000313|RefSeq:XP_014017289.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014017289.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RICTOR family.
CC       {ECO:0000256|ARBA:ARBA00008878}.
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DR   RefSeq; XP_014017289.1; XM_014161814.1.
DR   OrthoDB; 90320at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa20.
DR   GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR028268; Pianissimo_fam.
DR   InterPro; IPR028267; Pianissimo_N.
DR   InterPro; IPR029453; Rictor_IV.
DR   InterPro; IPR029451; RICTOR_M.
DR   InterPro; IPR029259; RICTOR_phospho.
DR   InterPro; IPR029452; RICTOR_V.
DR   PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR   PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR   Pfam; PF14663; RasGEF_N_2; 1.
DR   Pfam; PF14666; RICTOR_M; 1.
DR   Pfam; PF14664; RICTOR_N; 1.
DR   Pfam; PF14665; RICTOR_phospho; 1.
DR   Pfam; PF14668; RICTOR_V; 1.
DR   SMART; SM01303; RasGEF_N_2; 1.
DR   SMART; SM01307; RICTOR_M; 1.
DR   SMART; SM01308; RICTOR_N; 1.
DR   SMART; SM01309; RICTOR_phospho; 1.
DR   SMART; SM01310; RICTOR_V; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          57..439
FT                   /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01308"
FT   DOMAIN          516..735
FT                   /note="Rapamycin-insensitive companion of mTOR middle"
FT                   /evidence="ECO:0000259|SMART:SM01307"
FT   DOMAIN          913..985
FT                   /note="Rapamycin-insensitive companion of mTOR"
FT                   /evidence="ECO:0000259|SMART:SM01310"
FT   REGION          1012..1033
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1094..1116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1177..1267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1227..1254
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1608 AA;  179061 MW;  FC96364F494D5551 CRC64;
     MAASIRGRPI RSLRMRGRND SGEENVPLDL TREPSDNLRE ILQNVAKPHG ITNMRKLGHL
     NNLIKLLSSI GHCEEKFGFT YEEIIICLRL ALLNEAKEVR AAGLRALRYL IRDNNVLQKV
     LRLQVDYLVA RCIDIQQSNE GERTQALRLV RKMITVNPLL FPSSVTNSLI AVGTDGLQER
     DRMVRAAIAI VCELALKNPE VVTKRGGLSA ILKSVIDCQL SRINEALITT ILHLLNHPHT
     RQYIRNDVEL EQILAPFTDF HYRHNADTSE SQLKEDREAC FLSSRMAIVA SFRSWSGIIN
     LCRAGNSGIQ SLIGLLCIPN MEVREGLMEV LYEIFRLPLP IVTQDFTEAL LSVDPSRCQD
     SWRLSDGFVA AEAKVILLHG ARSRPDLIDN YLALLLSAFI SSGLLEGLVE VVTSSEAQIS
     VRATILLGEL LHMANTILPH SHSHHLHCLP TLINMAASFD IPKEKRLRAS AAVNHLKRFH
     DKKKQGPKPH SLYLDHIIRK SVTHTRVHRD IYTIMDTEEA LMLNLRDSQI LNHKQNLDWN
     WLLIATILKW PNINLRNNKD EQMHKFVRRL LYFYKPSSKL YAGLELDHPK ARQLTLVGCQ
     FIEFLIESDE DGQAYLEELV KDMVAWLSLS SGLKPDPCLQ SNGLLTTLSQ HYFLLLGTLS
     AHLHGIKLLE KCSLFQCLLN LCSVKNQDVV LKLAVSTLDY SRDGLARVIL SKILTAATDT
     CRLYATKHLR VLLRAGVEFF SNWGMELLVT QLHDHSKAVS LEALDILDEA CEDKANLHAL
     IQLKPALSHL GDKGLLLLLR FLSIPKGFSY LNERGYVSKQ LDRWQKEYNL RYVDLIEEQL
     NEALTTYRKP VDGDNYVRRS NQRLQRPNVY LPVHLYGQLV HDKTGCHLLE AQSVVPDLSY
     TVRCPMLDTW EGIKQLKAAL WALGNIGSSN WGLNLLQDEN VIPDILALAQ HCEVLSIRGT
     CVYVLGVISK TRQGCEVLKR YGWDAVRHSR RTLWPVTPDE VDTLMTSELS SVPSTLSLDS
     ESTSSQHNSE SESQPHMYIL DDYKCDMLDQ SNDASLYLHS KPGKDRSPFT ILASTRFVRN
     RFLNSLTLPR KKLRSTSDPK AVGGSCTPTE PKLGGLRRNR TVTEPSIYSS SQGDVFTPVF
     NGRGLPKSPT VSLETSFVVT SGSGEGSEGQ LVERRLDQAG GGGTGLRGPG EPPSREQSSR
     ERLAGGDGGS SSSGGGGGGG GGGGGGTQFK SRSQSFNTTT SGISSMSSSP FRETAGNPEP
     EPDSSDCVSL NTVVSAKTVK MLYSLSPTQA QTNHLPLSKS NSVSLFPAGY SHTLPRRSQS
     LKSPSMTAIK SLADCSFMYT SPRDALGYAT LKKLQQQRIH PSLSHSEALA SPAKDVLFTD
     AITMKTGSLD SRLMPRRLSA KRVSCPVVQP HRRMSISMPW FLKALSFASL DKEDLLSPIN
     QSTLHRSSSV RSMVSSATYS CNDDYVGLAL PMDINDMFHI RDAPYFQQKT SLPADDKCPF
     YFGDSECDGG RPYPRIPLLK QQFSISELMA SRENNQNHIL GVEETGLQEH TDDNCLYCVG
     TTVLGHHTQP QINNTCRDLL QGLTGPRPKQ GCWGFLGGIY IYIYILVI
//