ID A0A1S3NSA9_SALSA Unreviewed; 439 AA.
AC A0A1S3NSA9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Friend leukemia integration 1 transcription factor-like isoform X4 {ECO:0000313|RefSeq:XP_014018292.1};
GN Name=LOC106581097 {ECO:0000313|RefSeq:XP_014018292.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014018292.1};
RN [1] {ECO:0000313|RefSeq:XP_014018292.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014018292.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_014018292.1; XM_014162817.1.
DR AlphaFoldDB; A0A1S3NSA9; -.
DR GeneID; 106581097; -.
DR OrthoDB; 2882052at2759; -.
DR Proteomes; UP000087266; Chromosome ssa20.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd08541; SAM_PNT-FLI-1; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR035573; SAM_PNT-FLI-1.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF161; FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 121..207
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 269..349
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 211..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 49602 MW; 6BCA6EAE084C9369 CRC64;
MNMFQTVPDT SSYVKEALSV VSEDQSLFEP PYAAAAPLPK TDMTASGTQD YVQPHKINPL
PPQQEWINQP VRVNVKREYD HINGSRESPV DCSVGGKCNK LVGGNDTSQM SYGSYMDEKN
APPPNMTTNE RRVIVPADPS LWSQDHVRQW LEWAIKEYGL LEMDTAMLQN TDGKELCKMS
KDDFLRLTTM YNAEVLLSHL NYLRESSSSL SYNTPSHMDQ SPSLAAKEDP SYDAVRRTGW
SNNMHSGKDP YQILGPTSSR LANPGSGQIQ LWQFLLELLS DSANAGCITW EGTNGEFKMT
DPDEVARRWG ERKSKPNMNY DKLSRALRYY YDKNIMTKVH GKRYAYKFDF HGIAQALQPH
PTESSMYKYP SDLAYVPSYH AHQQKVNFVS PHPPPMPVTS SNFFGPTAPY WSSPGGIYPN
HSVPRHPNSH VPSHLGSYY
//
