ID A0A1S3NSW6_SALSA Unreviewed; 466 AA.
AC A0A1S3NSW6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transmembrane protease serine 5-like isoform X2 {ECO:0000313|RefSeq:XP_014018494.1};
GN Name=LOC106581154 {ECO:0000313|RefSeq:XP_014018494.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014018494.1};
RN [1] {ECO:0000313|RefSeq:XP_014018494.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014018494.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR RefSeq; XP_014018494.1; XM_014163019.1.
DR AlphaFoldDB; A0A1S3NSW6; -.
DR STRING; 8030.ENSSSAP00000076509; -.
DR PaxDb; 8030-ENSSSAP00000076509; -.
DR GeneID; 106581154; -.
DR OMA; CSERWNS; -.
DR OrthoDB; 4629979at2759; -.
DR Proteomes; UP000087266; Chromosome ssa20.
DR Bgee; ENSSSAG00000065601; Expressed in camera-type eye and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR PANTHER; PTHR24252:SF14; TRANSMEMBRANE PROTEASE SERINE 3-LIKE; 1.
DR Pfam; PF15494; SRCR_2; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF56487; SRCR-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50287; SRCR_2; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU363034,
KW ECO:0000313|RefSeq:XP_014018494.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|RefSeq:XP_014018494.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..161
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 227..464
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 466 AA; 51534 MW; 1B763F7BDB62B05B CRC64;
MNLDGDTLSV IENPVAVSHS FHPEKTGVGE ARGAQSQSCH AWLRGIHSTN HMSANRLVRV
LAAVCAVGLL GGLAVGVWFL VRLLLRPTSS QSPAGLGDTK ETSFCNVTED ISVADPRKVF
YRISPENSLL EIQLEKVPTW LPVCYERWNS SLGTLVCRQL GYLRLTKQKG VNLTDIGPNY
TDGFIQITSE HKSRLENIWQ LRGSCVTGKV IALKCFECGT RAKLPRIIGG VEATLGRWPW
QVSLYYSKRH TCGGTIITSQ WVVTAAHCVH NYRLPQVSSW VVYAGIVTRS SAKMTQYIGY
AVENILYNKN YNPRSHDNDI ALMKLRTPLN FSDTIRPICL PQYEHDLPGG TQCWISGWGY
TQPDDVLIPA TLKEAPVPLI STKKCNSSCM YNGEITPRML CAGYTEGKVD ACQGDSGGPL
VCQIDNVWRL VGVVSWGTGC AEPNHPGVYT KVAEFLGWIY DMIESY
//
