ID A0A1S3NUU2_SALSA Unreviewed; 715 AA.
AC A0A1S3NUU2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|RefSeq:XP_014019015.1};
GN Name=LOC106581470 {ECO:0000313|RefSeq:XP_014019015.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014019015.1};
RN [1] {ECO:0000313|RefSeq:XP_014019015.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014019015.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_014019015.1; XM_014163540.1.
DR AlphaFoldDB; A0A1S3NUU2; -.
DR STRING; 8030.ENSSSAP00000030834; -.
DR PaxDb; 8030-ENSSSAP00000030834; -.
DR KEGG; sasa:106581470; -.
DR OrthoDB; 5355021at2759; -.
DR Proteomes; UP000087266; Chromosome ssa20.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170,
KW ECO:0000313|RefSeq:XP_014019015.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 444..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 445..709
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 715 AA; 79803 MW; 4C58C6250B2C7A97 CRC64;
MLLSALSDTA ALLKSGMALR TDVVLRLLVV ISHFATCACL SNRKEFPSFF RTIPSDFYQS
RALAKLVKHF GWNWVGVVNS NNDYGNNGIA TFMEAAWHEG VCVEYQESIH RTDSREKLLE
VVRVIRRATA RVVVLFLTLG DLIPLLNELA LEGDPGLQWV GSESWITARL LADNKAYGFL
RGAVGFAIRN ARLDGLEGFL DKVHPSQAPD NTLLREFWET VFQCSFEGVS STLCTGTESL
AKLKNQYTDV SELRISSKVY TAVYAIAHAL HNLLTDLKND TDSGNRPVYT SQQVLQYLKK
VRFRVKTGEE IWFDANGDVV ACYDLVNWQQ EEDGTLQFHA VGLYDSSMPP EQRFTFNQGK
LVWAGGQAEA PAAVCSESCP TGTRKAVQKG KPVCCYDCVP CAEGEISNIT DSNGCYRCDL
EYWSNEKRDR CVLKPVEFLS YEEIIGIVLV FFSLLGSGVT TLVAVVFSIH KDTPIVRANN
SELSFLLLFS LTLCFLCSLT FIGRPSEWSC TLRHTAFGIT FVLCISCVLG KTIVVLMAFR
ATLPASNVMK WFGPPQQRLS VLAFTLIQVL ICVLWLTVSP PFPYKNMKTY KEKIILECDV
GSAIGFWAVL GYIGLLAVLC FVLAFLARKL PDNFNEAKFI TFSMLIFCAV WITFIPAYVS
SPGKFTVAVE IFAILASSFG LLFCIFAPKC FIILLRPEQN TKKHMMGKTS NDTRY
//
