ID A0A1S3NW47_SALSA Unreviewed; 2333 AA.
AC A0A1S3NW47;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Bromodomain adjacent to zinc finger domain protein 2B isoform X14 {ECO:0000313|RefSeq:XP_014019633.1};
GN Name=baz2b {ECO:0000313|RefSeq:XP_014019633.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014019633.1};
RN [1] {ECO:0000313|RefSeq:XP_014019633.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014019633.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WAL family. {ECO:0000256|ARBA:ARBA00007444}.
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DR RefSeq; XP_014019633.1; XM_014164158.1.
DR GeneID; 106581809; -.
DR OrthoDB; 2912910at2759; -.
DR Proteomes; UP000087266; Chromosome ssa21.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05503; Bromo_BAZ2A_B_like; 1.
DR CDD; cd01397; HAT_MBD; 1.
DR CDD; cd15630; PHD_BAZ2B; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037374; BAZ2A/B_Bromo.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45915:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF15613; WSD; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00391; MBD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 846..917
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 1206..1271
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 2077..2127
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2241..2311
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 164..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1138..1157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1548..1572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1603..1641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1659..1684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1704..1751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1816..1838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2129..2221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1079..1106
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 164..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..291
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..752
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..979
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1421..1442
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1443..1457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1605..1640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1660..1684
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1707..1751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2157..2182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2197..2216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2333 AA; 255930 MW; C308E1A794F60033 CRC64;
MESGERLASP SSASSSLHIT SSTVSSAVYS SAPAPVSAKT PSSKCSLTPS PATLGSPLTT
CGDLFRAAGD HHFNMSTVSS AFPIFNHPAF GLYTTSSGHS EFGGLGSLGM SAALAAHSQL
GAFPGMGTFP EWWRAAEAQG RGAAAFFPHL LGLPPIFLPQ LQQSHDPSPF QARTPSKNGR
ATAKGVNGAV NGSSVSAVSG VSSTTATTFS TQGNTEKLKG TNNGSGKIRM SHQDMNQVKE
KTKEKKLGKK LVEASSNSDS ESGSSSDISS EGLNSSESDD LDDDDDDQSN DSDDSNSAKE
SIKRKIKGLT QSPANSKKKK PRAAEGEEAR DSRTVLLQKH PDEAFLHSLH YPLHPSPQPP
ALPQSMALVF QSSRTREEEL KQHTSVIQAT GRASIKPLAL VTQPRREASS SPQPTRPFSL
SSSPKSYPLS SSPKPNAVSS SPKPFSLCSS PKPLSSSPKP LSSSPKSLSL STSSKPPSRS
SSPKPPTLSP SHKPKSQTAS PKLPTLSDSI KAGGRTFLDE TLLHINNFKL KQEHFKQAFP
LPLTHQDLFK SPKKKKMAAS SSSSLPPPKL SPETLSSHTL PSPHTNNSNL FLATSFLGPH
PNGVIHSTVQ DAPLALITKP RSTSQSRSTN NKSLLAATSP SFSMPVNLST RTKEHSSGGM
ASTSPGLAHR AGKSKAQHKA LHKGKDHQTH LVQSLVELFQ GTESDIPNSK DSDDSVEDDD
DEDDDNDEED SDDSLSESES NVESDSDDSE DDVKDRNETT AGPEAERTPL KLTKGSSSLL
NNTSSGLSAS CSPLNLQVIK AAGGLPTPAI VTSSGALAYH STPSSSSSSS STLCSTPPGS
GKRRRVTDER ELRTPLQFGW QRETRIHNVT GRLQGDVAYY APCGKKIRQY PDVMKYLSRN
GISDITRDNF SFSAKIRVGD FYEAREGPQG LQWSLLTEEE VIPRILAMEG RRGRPPNPEH
QRTGDESPRS RRRKGQRPNV GEADFPGATD AKLLRKLEAQ EMARQAAQIK MMRKLEQQAM
ARAAKEARKQ QAIMAAEEKR KQKERVKILK QQEKIKRIQQ IQMEKELRAQ QILETKRKKT
EEAANAKIME AEKRNKEKEM RRQQAVILKH QELERHRLDM VWERERRRQH MMLMKTMDAR
KKAEERERLK QEKKDEKRLN KERKLELRRL ELEIAKELKK PNEDMCLADH KLLPELSRIP
GLFLPGSSFS DCLMVMQFLR SFGKVLGFDV NAHVPNLSVL QEGLLNLGDS MGQVQDLLVR
MLSAVVCDPG LPPGHRTKTA LGDHLANVGI NQDNVSEALQ IYMEAHRGET ELQTELAEVT
ASLKTKAFQA HTPAQKASVL AFLVNELSCS KSVVSEIDKN IDHMTNLRRD KWVIEGTLRK
LRTIHAKKTG KKDSGVGGEE TQSLGTPNPG RKRKRKGGDS EEDEDDDEDS EDQGDEDEEE
EEEERGKKGK KVETCEEEDD GDQTASVEEL EKQIDKLTKQ QSQIRRKLFE SSHSLRSMMF
GQDRYKRRYW VLPQCGGIFV EGMETGKGAE ELERERLRST ELVHVKEEEV ERRPEVEGRP
GVSSLEGSTD GDMATPDKHS LNLFLQKPGS FSKLSKLLEV AKMSPDSDNH SQSCSPVKVS
TTVSSPIHPT TQTTLPSSPC AAPSPLCLEV KAEPSTALFS PPYLSGNSSP GKMSSSSQQQ
QQLQPNDQLL RVLTEKSGHW FSLLPRSPCD ESSTTTPPAF SPQSSSTTRP KSPTSLSPNP
PATTSASPTT GINNFSLSAL QVKSGVHMMG LPFCGWPGGM MSPTLPFSAS LLPPSMLSAA
YHHVEGNGNP LLAAASLSSS KSKSPVPAGE KPPSAPPTVV EVAKTQDYPD PLPIPEEMLS
GWWRVADMEE LRSLVKALHS RGIREKALQK QIQKHMEYIA QACAKNRDVV VIDESELEEN
GVSEETVESW CVEEQAMEMD IAVLQQVEEL ERKVTSASLQ VKSWMYAEPQ SERGDLVYHE
HKPFTKLLPA GEEQPAGEKE RASGDNSLVR HVNNPLDIAV TRLAELERNI ERRGEEGLAP
GMKVWRKAVG EVRSAAQLAL CIQQLQKSIA WERSIMKVYC QLCRKGDNEE LLLLCDGCDK
GCHTYCHKPK ITTIPDGDWF CPACISKASG QSPENKKQQS RAGAAGGGKR STEVKRSRTL
SSVASADVSE DDAASTSSST PKKWSKEPKK RKSLGEESPA TNQSKQDSTS PVCGKKAKTA
TSARDDDKDL NLCRVLLAEL EVHQDAWPFL NPVNPKSVPG YKKVIRKPMD FSTIREKLVN
SQYLNLETFI IDVNLVFDNC EKFNEDNSDI GRAGHNMRRF FEKRWTELLK QTN
//
