ID A0A1S3NW53_SALSA Unreviewed; 2298 AA.
AC A0A1S3NW53;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Bromodomain adjacent to zinc finger domain protein 2B isoform X19 {ECO:0000313|RefSeq:XP_014019638.1};
GN Name=baz2b {ECO:0000313|RefSeq:XP_014019638.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014019638.1};
RN [1] {ECO:0000313|RefSeq:XP_014019638.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014019638.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WAL family. {ECO:0000256|ARBA:ARBA00007444}.
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DR RefSeq; XP_014019638.1; XM_014164163.1.
DR GeneID; 106581809; -.
DR OrthoDB; 2912910at2759; -.
DR Proteomes; UP000087266; Chromosome ssa21.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05503; Bromo_BAZ2A_B_like; 1.
DR CDD; cd15630; PHD_BAZ2B; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037374; BAZ2A/B_Bromo.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45915:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF15613; WSD; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00391; MBD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 846..921
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 1170..1235
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 2042..2092
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2206..2276
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 164..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1102..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1349..1430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1512..1536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1623..1648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1668..1715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1781..1803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2094..2186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1045..1072
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 164..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..291
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..752
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..945
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1406
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1407..1421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1624..1648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1671..1715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2122..2147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2162..2181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2298 AA; 251881 MW; BDA5C2CFFA8B7F34 CRC64;
MESGERLASP SSASSSLHIT SSTVSSAVYS SAPAPVSAKT PSSKCSLTPS PATLGSPLTT
CGDLFRAAGD HHFNMSTVSS AFPIFNHPAF GLYTTSSGHS EFGGLGSLGM SAALAAHSQL
GAFPGMGTFP EWWRAAEAQG RGAAAFFPHL LGLPPIFLPQ LQQSHDPSPF QARTPSKNGR
ATAKGVNGAV NGSSVSAVSG VSSTTATTFS TQGNTEKLKG TNNGSGKIRM SHQDMNQVKE
KTKEKKLGKK LVEASSNSDS ESGSSSDISS EGLNSSESDD LDDDDDDQSN DSDDSNSAKE
SIKRKIKGLT QSPANSKKKK PRAAEGEEAR DSRTVLLQKH PDEAFLHSLH YPLHPSPQPP
ALPQSMALVF QSSRTREEEL KQHTSVIQAT GRASIKPLAL VTQPRREASS SPQPTRPFSL
SSSPKSYPLS SSPKPNAVSS SPKPFSLCSS PKPLSSSPKP LSSSPKSLSL STSSKPPSRS
SSPKPPTLSP SHKPKSQTAS PKLPTLSDSI KAGGRTFLDE TLLHINNFKL KQEHFKQAFP
LPLTHQDLFK SPKKKKMAAS SSSSLPPPKL SPETLSSHTL PSPHTNNSNL FLATSFLGPH
PNGVIHSTVQ DAPLALITKP RSTSQSRSTN NKSLLAATSP SFSMPVNLST RTKEHSSGGM
ASTSPGLAHR AGKSKAQHKA LHKGKDHQTH LVQSLVELFQ GTESDIPNSK DSDDSVEDDD
DEDDDNDEED SDDSLSESES NVESDSDDSE DDVKDRNETT AGPEAERTPL KLTKGSSSLL
NNTSSGLSAS CSPLNLQVIK AAGGLPTPAI VTSSGALAYH STPSSSSSSS STLCSTPPGS
GKRRRVTDER ELRTPLQFGW QRETRIHNVT GRLQGDVAYY APCGKKIRQY PDVMKGLQWS
LLTEEEVIPR ILAMEGRRGR PPNPEHQRTG DESPRSRRRK GQRPNVGEAD FPGATDAKLL
RKLEAQEMAR QAAQIKMMRK LEQQAMARAA KEARKQQAIM AAEEKRKQKE RVKILKQQEK
IKRIQQIQME KELRAQQILE TKRKKTEEAA NAKIMEAEKR NKEKEMRRQQ AVILKHQELE
RHRLDMERER RRQHMMLMKT MDARKKAEER ERLKQEKKDE KRLNKERKLE LRRLELEIAK
ELKKPNEDMC LADHKLLPEL SRIPGLFLPG SSFSDCLMVM QFLRSFGKVL GFDVNAHVPN
LSVLQEGLLN LGDSMGQVQD LLVRMLSAVV CDPGLPPGHR TKTALGDHLA NVGINQDNVS
EALQIYMEAH RGETELQTEL AEVTASLKTK AFQAHTPAQK ASVLAFLVNE LSCSKSVVSE
IDKNIDHMTN LRRDKWVIEG TLRKLRTIHA KKTGKKDSGV GGEETQSLGT PNPGRKRKRK
GGDSEEDEDD DEDSEDQGDE DEEEEEEERG KKGKKVETCE EEDDGDQTAS VEELEKQIDK
LTKQQSQIRR KLFESSHSLR SMMFGQDRYK RRYWVLPQCG GIFVEGMETG KGAEELERER
LRSTELVHVK EEEVERRPEV EGRPGVSSLE GSTDGDMATP DKHSLNLFLQ KPGSFSKLSK
LLEVAKMSPD SDNHSQSCSP VKVSTTVSSP IHPTTQTTLP SSPCAAPSPL CLEVKAEPST
ALFSPPYLSG NSSPGKMSSS SQQQQQLQPN DQLLRVLTEK SGHWFSLLPR SPCDESSTTT
PPAFSPQSSS TTRPKSPTSL SPNPPATTSA SPTTGINNFS LSALQQVKSG VHMMGLPFCG
WPGGMMSPTL PFSASLLPPS MLSAAYHHVE GNGNPLLAAA SLSSSKSKSP VPAGEKPPSA
PPTVVEVAKT QDYPDPLPIP EEMLSGWWRV ADMEELRSLV KALHSRGIRE KALQKQIQKH
MEYIAQACAK NRDVVVIDES ELEENGVSEE TVESWCVEEQ AMEMDIAVLQ QVEELERKVT
SASLQVKSWM YAEPQSERGD LVYHEHKPFT KLLPAGEEQP AGEKERASGD NSLVRHVNNP
LDIAVTRLAE LERNIERRGE EGLAPGMKVW RKAVGEVRSA AQLALCIQQL QKSIAWERSI
MKVYCQLCRK GDNEELLLLC DGCDKGCHTY CHKPKITTIP DGDWFCPACI SKASGQSPEN
KKQQSRAGAA GGGKRSTEVK RSRTLSSVAS ADVSEDDAAS TSSSTPKKWS KEPKKRKSLG
EESPATNQSK QDSTSPVCGK KAKTATSARD DDKDLNLCRV LLAELEVHQD AWPFLNPVNP
KSVPGYKKVI RKPMDFSTIR EKLVNSQYLN LETFIIDVNL VFDNCEKFNE DNSDIGRAGH
NMRRFFEKRW TELLKQTN
//
