ID A0A1S3NWS6_SALSA Unreviewed; 975 AA.
AC A0A1S3NWS6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Protocadherin-8-like {ECO:0000313|RefSeq:XP_014019834.1};
GN Name=LOC106581910 {ECO:0000313|RefSeq:XP_014019834.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014019834.1};
RN [1] {ECO:0000313|RefSeq:XP_014019834.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014019834.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014019834.1; XM_014164359.1.
DR AlphaFoldDB; A0A1S3NWS6; -.
DR STRING; 8030.ENSSSAP00000103996; -.
DR PaxDb; 8030-ENSSSAP00000103996; -.
DR GeneID; 106581910; -.
DR KEGG; sasa:106581910; -.
DR OrthoDB; 4259465at2759; -.
DR Proteomes; UP000087266; Chromosome ssa21.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF46; PROTOCADHERIN-8; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..975
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010248245"
FT TRANSMEM 696..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..135
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 136..244
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 245..352
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 367..463
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 464..573
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 579..683
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 725..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..862
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 975 AA; 107859 MW; 336C0290CD2F9296 CRC64;
MMCGILTGWH GWIFGLQMLL FSLAVSEGNT LKYQTNEEGS PGTVIGNLAK DMSLSPSFGS
NTNFRMMKQF NDSFIRVRES DGELSVGERI DRERICRHTL QCLITFDVVS FSKERYKLIH
VEVEVKDIND NSPEFPNKES TVEISENADV GFRIHLDPAE DPDVGSNYIQ SYQISVNSHF
SIDVLLRADG VKYAELVLMK ELDRETQSSY AVELIATDGG NPYRSGSTKI TIKVTDFNDN
RPVFDQNNFS VTLPENAPVG FVLLDLNAVD PDEGLNGEVS YGFGKQVSAE IRELFEVDSK
SGRVRLKNPV DFETKKTYEL DVQATDLGSN PTPAVCKIII HIKDVNDNAP EISITPMTSI
STGIAYISET ADKDSLVALI STSDRDSGVN SQVHCTLYGH DHFKLQQAYE DSYMIVTATF
LDREKISEYN LTVMAEDFGS PPLRKITQYT IRLSDENDNA PHFTKPIYEV SVVENNAPGA
YITTVEARDA DLGTNGKITY RLLDSVIMGS PVNTFVSLNA ISGSIYALRS FNYEVMKHLE
VHIQASDEGS PQLQSSAIIN IKILDQNDNA PSIIEPVLNK GSAEIFLPKD APAGYVVTQI
KATDAEEGIN ARMSYKITEG GHLGFSINKV TGKLHVSHEL NYDLSETLRV LVAVNDNGTP
SLTSTATIHL TLIEGAPPSV PAMVQNDSVE VFEWDIAIII VLSGSCSLLL LAIILITTTC
SRRKREKREA GYSENEDMPH VEKGESRQID SLITNHKSNV FDVHPFPEKA PLASSNTIKT
DPDDGRQEKE CVFDNRIMEG KLEGYSTLPG YRKETLRPIT IWKGNSFTTI SARDPQFSGK
DSGKGDSDFN DSDSDISGDG HKKDSPPINS LWACTSECKI LGHSDRCWSP SATRANTSLS
HGPHLSTFSK TASLPQNTLQ RDTYYQQAHL PKINGLQSVY EKVQHQELDY ILVCPPTPAR
ILETDEISLP EYGQS
//
