ID   A0A1S3NZL9_SALSA        Unreviewed;      4747 AA.
AC   A0A1S3NZL9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Nebulin isoform X15 {ECO:0000313|RefSeq:XP_014020822.1};
GN   Name=LOC100194727 {ECO:0000313|RefSeq:XP_014020822.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014020822.1};
RN   [1] {ECO:0000313|RefSeq:XP_014020822.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014020822.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014020822.1; XM_014165347.1.
DR   OrthoDB; 3816962at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa21.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   CDD; cd11933; SH3_Nebulin_C; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR013998; Nebulin-like.
DR   InterPro; IPR000900; Nebulin_repeat.
DR   InterPro; IPR035629; Nebulin_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR11039; NEBULIN; 1.
DR   PANTHER; PTHR11039:SF37; NEBULIN; 1.
DR   Pfam; PF00880; Nebulin; 46.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00510; NEBULIN.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00227; NEBU; 125.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS51216; NEBULIN; 78.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          4688..4747
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          4612..4636
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   4747 AA;  546398 MW;  8FB3319B3538749C CRC64;
     MDENEEFEEE FEEEEIIEEE YFEETVTSTT SHQTTSRAAA VTQQPGVPVR RVVRKKVKVD
     TSKFMTPYLA HSQKMLDLFS YNKYRRAYDK AKGKPYAITA DTPEMMRIKK AQEQLSEVKY
     RMEGNKVRCT SLYDGEAREI AHVKHVSELI SKVLYRAKWD ETKDRYLLPP DAPELVLAVK
     NAANYSKKLY TEQWDEDKTM CYPYSDSPEL RRVAKAQEVL SDILYKKGHA ERTAKYTSLA
     VPNDMELAKK NFEHRSDLKY HEDYNKNVKG HWCETPYIEV AVARVAMDNL SNKMYTAAYE
     DIKDQINFMQ TETPEYKQHK KAGHAASSIK YKKDYENSKS VADYNVLPAT DNPLLRQLRY
     AGTILSDKVY KASYEKSRGS SINYCDTPKF KMDSVVQQFS DAHYKDKYEN EVKGHYIGSY
     EDIYMQHCKK MEEIKSEQNY KADYEDIKTR CFYPQTMSPE YEAHKKVAQC KDKVYRQHPD
     TVKFTQVTDS PVQLQAAINA KQLSDLNYHA AYELDKFKCA LPPDYPFFIQ SRANAYNLSD
     SCYRYDWEKV KAKQFEVKGD AISILAARAH TNIASDVKYK KEFEKNKGKM VGALSIHDDP
     KILHSMHVAK IQSDREYKKN YEKTKTKYIT TLDMMSNTLA KKSQGIASMT GYRTIHNRYL
     LPHDAMSLDL AKKANIIQSD NEYHSDYNNS TKGTGWVAFG SMEVEKAKKA GDILNERKYR
     QHPDTVPFTS IADHPVMMQA QVNQIMRSDL HYKKGLEEIH QKYSLPHNDP QFLQAKCNAY
     NISKNYYKQS WEETIAKGYD MRPDAISVIH AKHGRHIASD IQYKKDYVKG KGKQIGCRNL
     QDDPLLVHYM EVARLQSDKN YKKDYHKSKL KYHSPVDMMS VVHAKHASTV QTFAGYRKIQ
     HHYTVLADAM NVELAKQMQT IASDNLYKSD YETSVKGTGW IPIGSLDVEK AKTAGLIGSE
     KLYRQHPSSF KFTKDMHSMD VVLANANNAI MNKQTYVDAW NKDKTSVHIM PDSMEVVLAR
     ANKINCSATL YKLANEQDKK KGYDLRNDAI AILAAKQGTS IASDFKYRAG YRKQVGHHIG
     ARCVEEDPLL MLAINSAKIA SDALYKKDFH QSKTKFHLPL DMIAFELAKK NQIQVNHAKY
     VTRLHNWTCL PDSTDVVHAR HVYDIASDAV YKADLKCLQG IGWVPIGSLD VEKAKKAGEV
     LSEKLYRQHP SNFKFTSSVQ DIGMVLAKQN NDNANKQAYT EAWETDKTKN HIMPDAMDIV
     LANANKSNYS WNQYRKAMVE DKKKGYDMRN DAISIIAAKH GREIISDHKY KSSYRKQVGH
     HIGARCVEDD PLLVLALNSA KIASDALYKK DFHQSKTKFH LPLDMIAFEL CKKNQIQVND
     FNYRTHLHNW TCLPDSTDVV HARHVYDIAS EAVYRADMKW LRGIGWVPTG SLDVEKAKKA
     GEILSEKKYR QHPSTLDFKS PLDGMDIVLA KHNGQIMNKR QYVEQWDADK IKIHVGNELP
     ELVLAKANAI TMSNKLYKQG FDETIKKGYY LPVDAISVKA AKHGREIISD YKYKAGYSKQ
     VGHHIGARCV EEDPLLMLAI NSAKIASDAL YKKDFHQSKT KFHLPLDMIA FELCKKNQIQ
     VNDFNYRTHL HNWTCLPDST DVVHARRVYD LHSDAVYRAD MEFIRGTGWV PIGSLDVLKA
     KKAAEILSDR LYKQKPDSLK YTTDMHSMPM VLAKANAEII NKGNYVAQWE ADKIKIHVGN
     ELPELVLAKA NAINNSYKLY KAELEELYKK GYNLKSDCIA IKAAKHGREI ISDYKYKAGY
     SEQVGHHIGA RCVEEDPLIM LALNSAKIAS DALYKKDFHQ SKTKFHLPVD MLTIELAKKC
     QMQVNDFNYR TRLHNWTCLP DSSDVVQARK VYALHSDAVY RADMEWLKGT GWVPIGSIDV
     EKAKKAGEIL SERKYREHPS NFKFTATTDD MPYALATANA QIMDKRQYVQ QWEADKIQIH
     VGNELPELVL AKANAITMSN KLYREGFNEM IGQGYHLDKD AIAVQHAKKS REIISDYKYK
     AGFRNQCGHH IGAHCVEDDP LLVLAANAAR ISSDINYKKD FHLTKTKFSI PLDMMSFDLA
     KKSQFQIQEF TYRTKLHNWT CMPDNTDVVR ARKVYSLHSD AVYRADLEWL RGCGWLPQGS
     VDVIKAKNAQ TILNERLYRQ PPSSIKFTSV VDSPEVVLSK QNADILSDRK YREVWDTEKT
     NIHLNNDLPS LVLSKANAIA ISNKLYTKDW DADKAKGYHI KEDAIAVLKA RKSRDIISDY
     KYHEGYRKQV GHHIGARCVE EDPLIMLALN SAKIASDALY KKDFNKSKTK FHLPVDMLTI
     ELAKKCQVQV NDFNYRTHLH NWTCLPDSTD VVQARKTYDL QSDAVYKADL EWLRGCGWNP
     HESVEVLKVK HAQAVLADRG YRVKLDQQKF TAPVDRIDMV CAKNAAEILN EANYRALWHT
     EKTKYTITDT PGLATAREVA KNLHPKLYTK DWDKVKATGF FMPGDAVPIK QCIHNNKVQS
     DHKYKADYRK QAGHHIGARC VEDDPLIMLA INSAKIASDA LYKKDFNKSK TKFHLPVDML
     TIELAKKCQV QVNDDHYRTR LHNWTCLPDS TDVTQARKAY DLQSDVVYKA DLEWLRGCGW
     VAADCVDHVK VRNAQKIMNE RLYKKDAKDN FAKYTHIVDR PEIILATINA FNLSDLKYKE
     TFNAEKGKYI GSEDTPQLAH SREVAKVISE KYYKLAWDES KATGYQLDAH YIPVVGAKKT
     REIVSDVKYH DTHEKAKGHY LAGTLVDFPE VMRCGEQEKQ KGLRDYHKEY NTNKAKNHIP
     ADIIPNMVAK RCQDMLSDVL YRTLLHNWTC HPDQQDIIRA RKNNEILSDV YYKDDLNWIK
     GIGCYAWDTP ELVRAKNAHL LQSDLKYKEE GKKEFNNYSI VTDTPVYVTA LLGHTWASDL
     NYREAYHKDK HMYTTILDTY NYAHNATLKD IYSTKTYTSA WDKIKAKDYT LPSDSHALKH
     AKQQKVILSN VKYREDYEKF KSLYTLPKSL EDDPQTLRCL KAGKMGLDRL YKADYEKTKA
     KNHIPPDMLD VLSARQTQNY VSEIGYRKHL HQWICMPDMQ VYVQARKVNE QLSDIFYKDD
     LNWLRGIGCY AWDTPEILRV KAADKLQSDN KYRAKGIEAF KDYSVVIDTP TYETAKLSSQ
     NLSDLHYRND YATNVKGTNS SPAVTVDTER ARLANFNQSD NLYKEANKNF MPTGYSLPHD
     NPLMKQAKQN SIVASSVKYK NDYEKSKATN YTMDPDGVSF VNIRNANKVT NPRLYRELYE
     KGKGKIHSTY DTPEIRQVKM TQEAVSDLCY KEKYFANRGT MIPMGVTPQM IHCNHVNEIT
     SDLRYKEDLL WLRGIGCFLY DTPEMSTVRN ITKFRSNYEV EAKKNHANFT VVLDTPEYQR
     VTELKTHMSD LMYRAQGNVE KTKCTTTLDS LDVKRVKWAQ QLSNKYMYTD LASKERAHFT
     PEKDTPIMSH ARAMKVVFSE IKYKDQYEKM KHKYTSIHDT PILVRAKKAY LQSSDLRYKE
     SFERSKGHYH SVKDALDIVC HRRVTDDISE VKYREKYINS LGTWRSMPDR PEFFHSRIIG
     ENVSDIKYKE DLDWLKGIGC YVWDRPEMVQ AEKNKVLFSE RHYKETFEKN RHRFKYTCDT
     PFFQAAKKAS VIINDRHYRA AYEKTKDKYS SVLDDPRNLL AKENAKNSQW KYREQYERAK
     NKFTSILETP EHESHKRSKA IGDNVYKMDY NKNKAKGYTL GHDTPHSTHM KKVKEITSVL
     KYKELYEKSK AQINMDPESF EIRAAKEAYK NISNLDYRKK YQATKNKWIW TVDRPDFIQA
     AKANFQQSDI EYTYDKEMMK GCVISIVDDK LAVLAKMNAD LSNVKYREKF EKAKGQYKTV
     LDTPTNLHAK SVRILASESK YKLAGKMEQQ TGQFTTLPTT RDTIHAKDMG KLVSEKQYKQ
     KFEKEKGKSK YNSMRVPPDV QHAMDVAKNQ SNFAYRQEAK AKLNYTSVAM RPDIMRATQA
     SKLASNIGYR EKARQEAAHG GSLVHRPDIA LATAVSKLNS QEELEARHSL HGAASIDTPQ
     SRHLKKMSAL TSNVQYKAKY DKEKGLRPKY DMKESVVYKT QKDAHQLASE VKYKGDLKKL
     HKPVTDMAES LSMQHNLSTS KLSSDYQYKK KHEDSKGHYL MIADSPEQLH HKEASELQSH
     VKYKEKYEKA KGKAMLDFET PTYVTAKEAQ HMQSAKDYHK EYEESIKGKN LSGLEVTPAM
     LHVRHATKIA SERDYRRDLE EGVKGKGLTV FEETPELLRA RNATAILSQK EYKKTLETEI
     KGKGMLALAT DTPDFMRARN ATDILSQQKY KQTAEADRAS YTSVIDTPDI LHAQNIRNMV
     SQKKYREEAE KCMSHYVPVL DTPEMMRVRE NQKNFSTIKY KDLLCRCTAI SDLPEVKRVR
     EMQKNISSVL YKDSSAKGTP QVFTPEMERA KRNQEQISSV LYSDSFRKQV QGKAAFVLDT
     PEMRRVKETQ RNISGVKYHQ DFEKSKGSFT PTTSDPVMDR VKKNTQEFSD INYRGIQRRV
     VEMEKRRVVE HEQETVTDLR VWRTNPGSVF DYDPAEDNIQ SRSLHMMSVQ AQRRSKEHSR
     STSAMSGVGD EKSEVSEDPA HHVSLYSNGF ATSSMGYTHT KTVELQQRSS SVATQQTTVS
     SVPSHPSTTG KTVRAMYDYS SADMDEVSFK DGDVIVNVQS IDEGWMYGTV QRSGKTGMLP
     ANYVEAI
//