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Database: UniProt
Entry: A0A1S3P2Q8_SALSA
LinkDB: A0A1S3P2Q8_SALSA
Original site: A0A1S3P2Q8_SALSA 
ID   A0A1S3P2Q8_SALSA        Unreviewed;      2792 AA.
AC   A0A1S3P2Q8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-JAN-2019, entry version 11.
DE   SubName: Full=inositol 1,4,5-trisphosphate receptor type 1-like isoform X3 {ECO:0000313|RefSeq:XP_014021889.1};
GN   Name=LOC106582863 {ECO:0000313|RefSeq:XP_014021889.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014021889.1};
RN   [1] {ECO:0000313|RefSeq:XP_014021889.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014021889.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
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DR   RefSeq; XP_014021889.1; XM_014166414.1.
DR   GeneID; 106582863; -.
DR   OrthoDB; 94996at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_014021889.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2315   2337       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2349   2367       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2395   2413       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2433   2460       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2481   2503       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2612   2635       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      112    166       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      173    223       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      231    287       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      294    373       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      379    435       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2729   2770       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2792 AA;  317413 MW;  E1E27A79022BEF7E CRC64;
     MSDKMSSFLH IGDICSLYAE GSTSGFISTL GLVDDRCVVQ PDTGDLNNPP KKFRDCLFKL
     CPMNRYSAQK QFWKAAKPGG NSTTDTVLLN KLHHAADLEK KQNESENRKL LGTVIQYGNV
     IQLLHLKSNK YLTVNKRLPA LLEKNAMRVT LDSAGNEGSW FYIQPFYKLR SLGDSVVIGD
     KVVLNPVNAG QPLHASSHQL VDNPGCNEVN SVNCNTSWKV VLFMKWSDNK ETILKGGDVV
     RLFHAEQEKF LTCDDFKKKE YVFLRTTGRQ SATSATSSKA LWEVEVVHHD PCRGGAGYWN
     SLFRFKHLAT GSYLAAEVNP DYKEECPEPR SSLDSDHEAL RARLRTPQER VMYQLVSVPD
     GMDISSIFEL DPTTLRGGDS LVPRSSFVRL RHLCTNTWVH STNNPIDKEE EKPVMLRIGT
     SAVKEDKEAF AIVPVPPAEV RDLDLANDAS KVLASIAGKL EKGTITQNER RFVTKLLEDL
     VFFVCDIPNT GQDVLEIMVN KPNRERQKLM REQNILKQIF KLLQAPFTDS GDGPMLRLEE
     LGDQRHAPFR HICRLCYRVL RHSQQDYRKN QEYIAKQFRF MQKQIGYDVL AEDTITALLH
     NNRKLLEKHI TAAEIDTFVT LVRKNREPRF LDYLSDLCVS MNKSIPVTQE LICNAVLDPS
     NADILIETKL VLSRFEIEAV TMGENPIETE EDEEEVWLFW RDNCKEIRSK SVRELAQDAK
     EGQKEDQEVV SYYRYQLNLF ARMCLDRQYL AINKISGQLD VDLILRCMSD EDLPYDLRAS
     FCRMMLHMHV DRDPQEQVTP VKYARLWSEI PSKIAIDNYD NDGTTRDEIK ERFCLTMEFV
     ENYLMSVVSQ NIPFDDREKN KLTFEVVNLA RNLIYFGFYN FSDLLRLTKI LLNILDCVHV
     STIYPITKLE KGEEKQGSNV MKSIHGVGEL MTQVVLRGGG FLPITPTHQP EEGVVKTQTE
     PEREDIMVMD TKLKIIEILQ FILNVRLDYR ISCLLCIFKR EFDESNPQGD NTPSGASQDG
     NNMTGSLDFE NIEEQAEAIF GGSEENTPLD LDDHGGRTFL RVLLHLTMHD YPPLVSGALQ
     LLFRHFSQRQ EVLMAFKQVQ LLVTSQDVDN YKQIKSDLDQ LRSIVEKSEL WVYKRQGDDD
     GGDGPSESDH KMKGDSGSSD KKKEESNSSY NYRVMKEILL RLSKLCVQEG ASGKKSKKQQ
     QRLLRNMGAH SVVLELLQIP YEKGEDVRMQ EIMKLAHEFL QNFCAGNQQN QILLHKHINL
     FLNPGILEAV TMQHVFMNNF QLCSEINERV VQHFIHCTET HGRHVQYLKF LQTIVKAENK
     FIKKCQDTVM AELVNSGEDV LVFYNDRASF QTLVTMMRSE RDRMDENSAL RYHIHLVELL
     AVCTEGKNVY TEIKCNSLLP LDDIVRVVTH EDCIPEVKIA YINFLNHCYV DTEVEMKEIY
     TSNHMWKLFE NFLVDICRVC NNTSDRKHAD TVLEGYVTET VMSIVTTFFS SPFSDQSTSL
     QLARQVFASI LGKITETRQP VFVQLLQGVF RVYHCNWLNP TQKASVEACI KVLSDVAKSR
     AIAIPVDLDS QVNNLFVKSN NVVTKSILSW RLSAKNAPRR DSNATASVSY RNIIERLQDI
     VSALEDRLRP LVQAELSVLV DVLHRPELLF PENTDARRKC ESGGFISKLI KHTKQLLEEN
     EERLCIKVLQ TLREMMTKDR GYGEKHIAFD DEMDVAELAP LPAEPEVPAA DELDPNQPQK
     QLEDQRRGEA LRQILVNRYY GNIKPGARRD SVTTFSNGPV PPGTEGKPRA VVSSGAAAAQ
     GELTLHEVQC RLDKEGASDL VIDLIMNATS DRIFQESILL AIALLEGGNT VIQKSFFMRL
     TGENKSEMFF KVFYERMKLA QQEIKATVTV NTSDLGSKKK EEEPPDKDTP TAKGKKGMEV
     AVVSSVAVAV VTEEVKEQLV EASTVTKKAF TRYRREAEAE EHLAAAEGQG PASTPDDQEG
     EMSVIITIMQ PILRLMQLLC ENHNRELQNF LRCQNNKNNY NLVCETLQFL DCICGSTTGG
     LGLLGLYINE KNVGLINQTV ESLTEYCQGP CHENQNCIAT HECNGIDIII ALILNDINPL
     GKKRMDLVLE LKNNASKLLL AIMESRHDSE NAERILYNMR PKELVEVIKK AYMQGEVEPN
     EPAEEDEDGE EEHAASPRNV GHNIYILAHQ LARHNKELQA LLKTYGEGDE ALEFYAKHTA
     QIEIVRLDRT MEQIVFPVPN ICEFLTNESK LRVYYTTERD EQGSKINDFF LRSEDLFNEM
     NWQKKLRGTQ EPTTGNANTV PSQPILYWCS RNMSFWSSIS FNLAVLMNLL VAFFYPLEGI
     RGGTLDGHLS ALLWVAMLVS LAIVIILPQP HGVRVLIAST ILRLIFSVGL EPTLFLLGAF
     NVGNKMIFLM SFVGNRGTFT RGYKAMIMDV EFLYHLLYLI ICSLGVFVHV FFYSLLLFDL
     VYREETLLNV IKSVTRNGRS ILLTAVLALI LVYLFSIVGY IFFQDDFLLN IDRIPNKTLE
     SGASMVGEFL SAEVCRKDSG ENCSAEAVVD AAIATQPSAV VIEDKERSCD SLLMCIVTVL
     SHGLRSGGGV GDVLRKPSKE EPLFAGRVIY DLLFFFLVII IVLNLIFGVI IDTFADLRSE
     KQKKEEVLKT TCFICGLERD KFDNKTVTFE EHIKVEHNMW HYLFFIVLVK VKDSTEYTGP
     ESYVAEMIRE HNLDWFPRMR AMSLVCSDAD GEQNEIRSLQ EKLESTMKLV SNLSGQLTEL
     KEQMTEQRKQ KQRIGLLGHP QHPQHANPQQ PA
//
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