ID A0A1S3P389_SALSA Unreviewed; 431 AA.
AC A0A1S3P389;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Bone morphogenetic protein 7-like isoform X2 {ECO:0000313|RefSeq:XP_014022015.1};
GN Name=LOC106582915 {ECO:0000313|RefSeq:XP_014022015.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014022015.1};
RN [1] {ECO:0000313|RefSeq:XP_014022015.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014022015.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_014022015.1; XM_014166540.1.
DR AlphaFoldDB; A0A1S3P389; -.
DR GeneID; 106582915; -.
DR OrthoDB; 2912454at2759; -.
DR Proteomes; UP000087266; Chromosome ssa22.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19397; TGF_beta_BMP7; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF135; BONE MORPHOGENETIC PROTEIN 7; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..431
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010175411"
FT DOMAIN 311..431
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 289..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 49062 MW; 55D01E952FA325FA CRC64;
MNLIMVVLLH LRASAMVLAW GFCILGETTF SNFTLDNEVQ SSFIQRRLRN QERREMQREI
LSILGLPHRP RPHIYTKQNA APMFMLDLYN AISTYGQQPT GFSYYKPVFT TQGPPMVTPQ
DSSFLNDADM VMSFVNIAKL DQDVLSSQHN REFRFDLSRI PEGEAVSAAE FRIYKDYIRE
RSENETFHVS VYQVLQEPSD SDDYLFLLDT RVVWAAEEGW LVFDITATSN QWVVNPDHNL
GLQLALESMD GQSMNPRLVG LLEGSGPQDK QPFMVAFFKA TEVRLRSVRS AHGHKGRNPN
RSKKPKTPQD ALKVAEAAAE NLSTDPKQGC KKHELYVSFR DLGWQDWIIA PEGYAAYYCQ
GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LHGISVLYFD DSSNVILKKY
RNMVVRTCGC H
//
