ID A0A1S3P3R3_SALSA Unreviewed; 729 AA.
AC A0A1S3P3R3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Rap1 GTPase-activating protein 1-like isoform X3 {ECO:0000313|RefSeq:XP_014022191.1};
GN Name=LOC106583006 {ECO:0000313|RefSeq:XP_014022191.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014022191.1};
RN [1] {ECO:0000313|RefSeq:XP_014022191.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014022191.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014022191.1; XM_014166716.1.
DR AlphaFoldDB; A0A1S3P3R3; -.
DR OrthoDB; 25782at2759; -.
DR Proteomes; UP000087266; Chromosome ssa22.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF67; GTPASE ACTIVATING PROTEIN RAP1-GAP; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF02188; GoLoco; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00390; GoLoco; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50877; GOLOCO; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 216..432
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 478..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 81418 MW; 1D5A4728683A8A08 CRC64;
MTDFRMTKSG HVFISPAVIT RGQRRRHSDT SDLFAMIERM QGSRMDEQRC ILPPPLKTEE
DYIPYPSVHE VLGRRSPFPL ILLPQFGGYW IEGTNHKSSA TPGPEQQPCA ASHIKLETNS
IAKIYRKQFM GKEHFNYYSM DTALGHLVFS MKYDVIGDQE HLRLLLRTKL KTHHDVIPIS
CLTEFPNVVQ MAKLVFEEVN VDRFYPVLYP KASRLVVTFD EHVISNNFKF GVIYQKFGQT
TEEELFGNSD ESPAFVEFLE FLGDKIELHD FKGFRGGLDV THGQTGTESV YTNFHNKEIM
FHVSTKLPYT EGDTQQLQRK RHIGNDIVAI LFQEENTPFV PDMIASNFLH AYVVVQVENA
CSDNVTYKVS VTARDDVPFF GPALPDPAIF KKGHEFHEFL FTKLINAEYA CYKAEKFAKL
EERTRSALLE TLYEELHINS QSMMGLGGDE DKLENGGGGG GGFFESFKRV IRSRSQSMDA
MGLSNKKPHT VSTSLSSSFT ETPKTPGISL LVPGKSPSRY HGRRGSAIGI GTIEESLIIP
GKSPTRKKSG PFGTRRSSAI GIENIQEVQE RSREVSPSTQ RTPDSGHISQ DPKSESSSNQ
SSPEMPTTRT SSAICCRAPY IPEAQDLSRS SSNASSFASV VEEHDNVCIE EYNTGLESLC
SSGTPHKKDS FAYVSWVEDS MSNTSATSQV GSPAPALPHQ TEGGKRVELK RAESRDKTER
SQDKSSSNC
//
