ID A0A1S3P530_SALSA Unreviewed; 803 AA.
AC A0A1S3P530;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Melanocyte protein PMEL {ECO:0000313|RefSeq:XP_014022722.1};
GN Name=pmel {ECO:0000313|RefSeq:XP_014022722.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014022722.1};
RN [1] {ECO:0000313|RefSeq:XP_014022722.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014022722.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR RefSeq; XP_014022722.1; XM_014167247.1.
DR AlphaFoldDB; A0A1S3P530; -.
DR STRING; 8030.ENSSSAP00000119774; -.
DR PaxDb; 8030-ENSSSAP00000119774; -.
DR GeneID; 106583277; -.
DR KEGG; sasa:106583277; -.
DR CTD; 321239; -.
DR OMA; RDQDWLG; -.
DR OrthoDB; 5354575at2759; -.
DR Proteomes; UP000087266; Chromosome ssa22.
DR Bgee; ENSSSAG00000081271; Expressed in camera-type eye and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..803
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010280931"
FT TRANSMEM 732..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 245..279
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 803 AA; 83267 MW; B4F9D773F03F0B43 CRC64;
MKTVLIVLVL ALLSAAFGAK PKTRFTRYRS WNSGIYPVWK DGDSRYRDCW IGGEVTFDVK
NDAPTLTGAK ATFNIDLRFP SNQTVLPDGQ VVWARNCTVN GTQYRQGQAV YPDQVSGPSG
EYSGVFPDGT PFTGTADRKP HYVFVWKTWG RYWQVADGTS SSLTIGTDNV PLGSYNMEVV
IYHCRGKDKF IPLGYASTTF SITDQIPFAV SLTQINDVNE ADQSFIQNRA IAFSISLHDP
SQYLSASDVT FNWDFGDNSG TLISREHQVT HTYLNTGTYR PQVVLMASIP NGCDTPADPT
AASSTVMPMN PSGAPAVVVV VSTPRAAPAD IALDVPASDV APAETADTDA AAAAEGVEVV
ASAADDPAVI PATEDPASVP AVEADATAED TAAAAIEVPA PVPAVEGATA APVAPATEEV
AAVDADAAAA AETAVVEATA ADVPAIDAAP SVAPVAEGEE ATVDLAATVL PEVPAVATVT
PVEEATAVAD AEVVAEVAAA TEVAQVETVA PAANVIVPAA TEAAAVVEVV PAELALEAEA
ELEAEVVETV IEVAADATAA PAAVSAPVES EVAAEAEIEA NTETQVALVV AKRQAPELTA
ADNCMIYRYG SFSTAVDVVQ GIESVEITQV ANVVSLATEV VQNAVDLTIT CQGSLPNEVC
TIISDADCIT PVETICNNVT PSPDCQMILR QFFNDSGVFC INVSLTNDVS LAVASAKVSV
TVGSNSSPAG TVAAVLGVMV LVCVAGAIAL TYKRFNQYRP LREDSTGGIM GSSGNTSVPM
LLWNLLSRQS PGERSPLLQG RVV
//
