ID A0A1S3P7X9_SALSA Unreviewed; 4582 AA.
AC A0A1S3P7X9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Plectin-like isoform X28 {ECO:0000313|RefSeq:XP_014023705.1};
GN Name=LOC106583613 {ECO:0000313|RefSeq:XP_014023705.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014023705.1};
RN [1] {ECO:0000313|RefSeq:XP_014023705.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014023705.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014023705.1; XM_014168230.1.
DR OrthoDB; 5321591at2759; -.
DR Proteomes; UP000087266; Chromosome ssa02.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd06503; ATP-synt_Fo_b; 1.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 4.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF20; PLECTIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 15.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 32.
DR SMART; SM00150; SPEC; 3.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 5.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 10..130
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 143..248
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 796..854
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1500..1533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1613..1708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1962..2029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2097..2125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2144..2171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4243..4265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4477..4512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1242..1293
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2320..2598
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1613..1702
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2144..2167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4243..4263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4582 AA; 524649 MW; 2C52C9A60AA93A3B CRC64;
MKIIPDERDR VQKKTFTKWV NKHLIKHGKA ESQSQVTDLY EDLRDGHNLI SLLEVLSGET
LARERDVVRN LRLPREKGRM RFHKLQNVQI ALDFLKHRQV KLVNIRNDDI ADGNPKLTLG
LIWTIILHFQ ISDIQVNGQS DDMSAKEKLL LWSQRMVDGY QGIRCDNFTT SWRDGKLFNA
VIHKHQPRLI DMSKVYRQTN VQNLEYAFNV AETDLGVTRL LDPEDVDVPH PDEKSIITYV
SSLYDAMPRD VQDGIQANQL ELRWTEYYEL VTIIRQWISH HVVIFGERRF PGSYEEIEIL
WRQFLKFKET ELPAKEADKH RSKLIYQSFE SAVHAGQVKV PPGYHPIDVE KEWGRLHVSI
LERERLLRIE FERLERLQRI VSKVQMESGV CEEQLNQLET LLQTDIRLLS AGKPAQHTAE
VERDLDKADG MIRLLFNDVQ LLKDGRHQQA EQMYRRVYRL HERLVNLRTD YNLRLKSQVT
TTQMIQTQTI QQSSSRVRPE LDEVTLRYAQ DLLTWVEESQ RRIDEAEWGS DLPTVESQLG
SHRGLHQTVE DFRAKIERAK ADEVLDLKGA KSQLSPVSKG TYSQYLGKLD LQYAKLLNSS
KSRLRNLDSL YVFVSAATKE LMWLNDKEEE EVNYDWSDRN TNMTAKKDNY SGLMRELELR
EKKVNNIQVT GDKMLKEGHP GKKTVEAFTA ALQTQWSWIL QLCCCIEAHL KENTAYYQFF
SDVKEAEERM KKMQETLKKK YCCDRSTTAT RLEDLLQDAV EEKEQLNEFK THVAGLNKRA
KTIIQLKPRN PTKSIKGKLP IQAVCDFKQM EITVHKGEEC ALINNSPQPN KWKVLNRSGI
EAVVPSVCFL VPPVNKEAMD SVSSLDSGHQ SMLVLWQRLH VDMKSMLSWQ YLTRDITQIR
TWNITMFKTM KVEEYRLFMR NLELHYQDFM RDSQDSQLFG PHDRMQIEGD YSKTTQYYDN
LLRSVEKGPV VKTKGEQDES MCVTYITQIK DLRLRIEDCE ARTVARIRKP VDKDPIQDCA
QKTTDQKKVQ VELEGIKKNL DQVAVKTEEV LSTTPQQSST APVLRSELEF TLKKMDHAYI
LSSVYLEKLK TVDVVIRNTQ GTEGVLKKYE QRLREVQTVP NDFKEVEMYR TQLKKMRAEA
EGEKPAFDSL EGELGKAAAV SEKMSRVHSE RDAELDHYRH LLSCLQDRWQ AVFSQMDLRQ
RELEQLGRQL GYYRESYDWL IQWIGDAKQR QEKIQAVPIS DSKTLKEQLA QEKKLLEEIE
QNKEKVDECQ KYAKAYIDTI KDYELQLVAY KAQVDPLSPL KKTKMDSASD NIIQEYVTLR
TRYSELMTLT SQYIKFITET QRRLEDEEKA AEKMKAEDRK KMAEMQAELN KQKQLAESHA
KAIAKAEQEA QELKLMMQEE VSRRQVVSVD AEKQKHNIQL ELHELKNLSE QQIKSKSQQV
EEANQSRVKI EEEIRIIRIQ LETTVKQKFT AEDELKQLRE KASEAERLRK LAQEEAEKLR
KQVNEETQKK RRAEEELKLK SEAEKEAAKQ KQKALEDLEK LKMQAEEAER RMKQAEVEKE
RQIKVAQEVA QKSAATELQS KRMSYVEKTS KLEESLKLEH VTVIQLQEEA ARLKKQQEEA
DMAREEAEKE LEKWRQKANE ALRLRLQAEE EAHKKSRAQE EAEKQKEDAE REARKRAKAE
ESALKQKDMA EQELERQRRL AEGTAQQKLS AEQELIRLRA DFDHAEQQRC LLDDELYRLK
NEVSAAEQQR KQLEDELAKV RSEMNILLQL KSKAEKESMS NTEKSKQLLE SEAAKMRDLA
EEAGKLRSIA EEAKRQRQVA EQEAARQRVE AERILKEKLA AINEATRMKT EAEIALKEKE
AENERLRRQA EDEAYQRKAL EDQASQHKQD IEEKINQLKK SSENELGRQK TLVDETLKQR
RVVEEEIRIL KLNFEKASSG KLDLELELNK LKNIAEETQQ SKLQAEKEAE KHRKLALEEE
KRRREAEEKV KKITAAEEEA GRQCKNAQEE VERLKKKADE AKKQKEDADK EAERQILVAK
QAAQKCNAAE QQVQSVLVQQ KEDNLTQKQL KEEYEKAKML AKQAELAKEK AEKEAALLRQ
QAEDAERQKQ AAEREAANQA KAQEEAVKLR KEAEFEAAKR AQAEADAIKQ KQQADAEMEK
HKKLAEQTVS QKSQVEKELT KVRLQLDETD KQKSVLDEEL QRLKDEVGDA VKQKAQVEEE
LFKVKIQMEE LVKLKLRIEQ ENQRLIKKDK DNTQKFLAEE AENMKKLAEE AARLSVEAQE
AAHMRQIAES DLSQQRALAE KMLKEKMLAI QEACKLKAEA EMLQRQKDLA QEQAQKLLED
KQLMQQRLEE ETEGFQKSLE AERRRQLEIT AEAENLKVKV SQLSDAQSKA ENEAKKFKKQ
ADEISARLHQ TELATKEKLT VVEKLEVQRL SSNKEADELR KAIADLEKEK DKLKKDAEDL
QNNSKEMVNA QQKQIQHEKT VLQQTFITEK AELLKKEKQI EEEKKKLEKQ FEEEVKKAKA
LKEEQERQRK QMEEEKNKLQ ATMDAALNKQ KEAEKEMLNK QKEMQELERK RLEQEKLLGE
ENKKLREKLQ QLEVAHKEPI SHTREIDIQT DDVPEEELIH MTMVETTKQV INGQSVGEEV
DSKKDTMSFD GIREKVPASR LYEVGLLTKK EFDKLKKGKA TVQDLSQTDK LRTILQGKNC
IGGVLTQSNQ KMAIYQAMKE KKITPGWALI LLEAQAASGY VVDPVKNKKL SVSEAVKEGL
IGPELHNKML SAERAVIGYK DPYTGNKISL FEAMKKGLID RDHAIRQLEA QIATGGLIDP
INSHRVPIET AYKQGQFDAE MNKILEDPSD NTKGFFDPNT QEKLTYLQLM QRCSTDPETG
LLLLPITDKA ALSTSTYTEE ETKDVFSKTT VSVPFGKFKG KTVTIWEIIN SEYFTEDQRK
DLIRQYKTGK ITVEKIITIV ITMAEEKEKK NEIAFEGLRG PVLATELLES KIIDKDLYNK
LHTGNTTIKE VSEMEPVHKS LKGTNCIAGV VIDSTKETMS FYQAMKKDMM RVGPALTLLE
AQAGTGFVVD PIKNQKFTVD EAVKATVIGP ELHEKLLSAE RGVTGYKDPY TGKTVSLFEA
MKKELIPKDQ GIRLLDAQLA TGGIIDPVKS HRIPHDVACK RGFFDDEMNQ ILNNPTDDVK
GYFDPNTQEN VTYSQLYKRC ITDNKSGLQL LPLSEQAINA KEEQTYTDVQ TKEAMSQATM
ELQSGPLKGK KLTIWEIIHS EYITEEQRID LMRQYRSGKI TIEKIIKIMI TIVYEKEAKK
QEQDGFKGLR AQVSAKSLFD SKIIDKATFD MLQQGKKTPT QVSENVNVSK YLQGSDSIAG
VYLEPTKEKI SIYQAMKKNL LRYNTGLSLL EAQAATGFII DPVKKQYLSV DEAVKAGIVG
PELHEKLLAA EKAVTGYKDP FTGKTISLFQ AMEKDLIIKE HVMPLLEAQL SSGGIIDPVN
SHRVPIDVAY QKSFFSKDLT HTFSEPSDDN KAFSDPNSDD KVTYKQLKEK CTRDPDSGMN
LLPLSKPQAP TVVEKTYLYT EEQTQNDLAT TQIDLPSSLE SLAGGSKSIW DIMNSNLLPE
QERKKLMEEY RSGSITKERM IIIIIEIMEQ REIIRGETVK SCNTIRRRVT IEELYNSRII
DLETFNLLKQ DKRNIRDIME MQSVKQYLFG TGCVAGVMSD STSRMSIYSA MKRGFLKPEI
ALSLLEAQAA TGFIIDPVRN ETLTVDEAVR KGVVGPEIHD RLLSAERAVT GYKDPYSGKI
ISLFQAMKKD LVLEDYALKM LEAQTATGGI MDPEFYFHLP ADIATQRGYI NKETNERLAD
DVKGFVDPVT EEKLSYAQLL KRCKIDPTNG MRLLSLGDKR LMFKGLRKQI TIEEMLRSQI
IDQQTVTELN EGLISVEEVS RRLQKYLEGT SCIAGVYVEG TNDRLSIYQA MKKNMIRPGT
AFELLEAQAA TGYVIDPIKN LKLTVNESIK MGIVGPEFKD KLLSAERAVT GYRDPYSGKT
ISLFQAMKKG LILKDHGIRL LEAQIATGGI IDPEESHRLP VEVAYNRGLF DEEMNEILTD
PSDDTKGFFD PNTEENLTYL GLMERCITDP ATGLVLLLLK EKKRERQTSS KSSVRKRRVV
IVDPESGKEM TVYEAFRKQL IDHQTYLELS EQECEWEEIT QTSSDGVVKS MIIDRRSGRQ
YDIDDALARG LIDQTSLSTY RSGNLSITEF ADMLSGNMGG FRSRSSSFGS TSGSTSSSYN
PMSPIPSIRP PAIMWNDPTE ETGPVAGILD TDTLEKVSVT EAMHRNLVDN ITGQRLLEAQ
ACTGGIIDPT TGERFAVTEA TEKGLVDKVM VDRINLAHKA FNGFEDPRTK VKMSASQALK
KGWLYYEAGQ RFLEVQYLTG GLIEPDVEGR VSLDESIRKG TIDARTAQKL RDVSAYSKYL
TCPKTKLKIS YKDAMDRSMV EEGSGLRLLE ASSQSSKGLY SPYNASNSGS AAGSRSGSRT
GSRTGSRRGS FDATGSGFSM NFSSSSYTSS SSYGGRRYDA GPHNGLMDEL AQALAALAMI
RPCSSEEQRA FPMMIPMHTT VA
//
