ID A0A1S3P9L8_SALSA Unreviewed; 1755 AA.
AC A0A1S3P9L8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Rho GTPase-activating protein SYDE2-like isoform X2 {ECO:0000313|RefSeq:XP_014024335.1};
GN Name=LOC106584049 {ECO:0000313|RefSeq:XP_014024335.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014024335.1};
RN [1] {ECO:0000313|RefSeq:XP_014024335.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014024335.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014024335.1; XM_014168860.1.
DR GeneID; 106584049; -.
DR OrthoDB; 2905108at2759; -.
DR Proteomes; UP000087266; Chromosome ssa23.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR PANTHER; PTHR46150:SF1; RHO GTPASE-ACTIVATING PROTEIN SYDE2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 1136..1255
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1293..1508
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 47..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1510..1529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1553..1698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 945..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1018
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1075
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1593..1611
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1647..1673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1755 AA; 193057 MW; E9773D1ABD78C8BC CRC64;
MFAELHCVAD HIMRGNESYV NGIVENTVGS VWEQSTVGVK TSVFPQQDEA PATMHINTSR
GPGDNQGSEG SGFRGRVNEE LLGVSLQIAT QYGGHDRYEM GRIHKQVPGY FSRQVQQEHI
GRPHEQRKHF GPIPRQYSAG DSIGFGGSSP NNNIIYHRRP GVVDREVVKL TGGHSPVSKS
NGTNDCFDTY LKTRVSDGQA DSCHQTVYNY KEENAQRSIN DLKGKANLLP GHNQILETNV
TTNWMQMYPL DVLCAHHPTG SYTEENIVIR NIESYGSSPE FTGDNIRVTH LQSPTFFPTE
LEMCDVNVAS HFICAREGTL RHHSIDSEDD DYYDNEILPF YISESVGPND RKGSDKVESI
ESGRDVPRGH VISDSVQETD RLHSQLKEAY YLLINAMHDI RFEGQVSVNG FIDQKSMCSW
SSFKHVGSDA LSSGEYSAQQ VSDMDSLLLC LLNENNNLIS KSLVNLSASR IRPPLLRSTS
DGTIKYSSGV HNGPCIQGLG SQSPSVVGAC EDGDGASRPK AVGASDPFEK QTSYDGGTSS
DDLLQDTGDN GKLNESRGSV NSLTGSSDNA EPQQGGNNNR DREMSNWALD QGGSGKPHGV
TVNKMQEWMH KGRLLSSEMK QRIAGSTPQP YGAHGGLDRA PRPSQGQVSS GPGGSKPEAL
MTRVDRAKPA AVVSCQGQAT QKSALIENDH SSFANGLDVG GGKAVETSLW RPPLNTITVS
KKRNWLQQSS GRPHHATDDP RYRLGAEEYN GHGQAPLSTL SSSPENLNPP GPTLSHPLCL
HLPLVRMGHA RVAPHSRCVE PTEENDADDE GEIWYNPIPE DEELELHHSH RPTSTPQVRL
MVQTRPQDPH VPQTRPSREV EAGVRRALEG CSPNLEGVGE SMGGGGGERS QQGIAIRCMG
PSLHLQRQML LACKPQECPS SSSRATATEA PDLAIPGFPP PSSLNPAKKG SSLNWSFPDK
IKSPRTVRKL SMKMKKLPEL SRKLSVKGTP SNNNNSSCNG ASASSNLETR TQYPKTNYGS
EPGPAPPRLS PRGGQGAAAS HNVISRYHLD SSVSTQQSYS KKKNSGTSKS ASKGGYLSDG
DSPELVAKSG KHGSSEAKGG NGKEKDPATG GGEKTGAGGV TRGSGSPKLH GTELDIDAFR
HYAFTEQPKC TQYISGLMSL HFYGAEDLKP PRFDSRDVYC AIQVDSVNKA RTALLTCRTT
FLDMDHTFNI ELENAQHLKL VVFSWDPTPK KNRVCCYGTV VLPALFRVSR SHQLAVKLEP
RGLIYVKLNL MEQWQNSLDG GYNGDREPQM FGVEAWRVVV RENTGLMLPL LIEKCITEIE
TRGCQVVGLY RLCGSASVKK ELREAFERDS LGVELCENTY PDINVITGVL KDYLRELPYP
LITKHLYETV LDSMAQRPLR IGAGGCENDP ADTEHTVSLL ENLPDVERLT LRRLLDHLKL
VASHHEVNKM TCQNLAVCFG PVLLSQRQEA SCHSNRVFID SEELASALHF KKHIEVLHYL
LQLWPVVDPH EKTSSPIPEP PGPADQLAVP PLRRRKDRPQ VLNLSNAEMA GVLRPRPGRL
DSPSNRYAGD WSRCGESYFP SPRSRVENDY ADVPSEDMEV TEEELEGVED KGQEGGEEQR
QEWLLDRGQA EPATAKQEPL LPEEVMEGPV DVEKEEREAE EERAAERRVE ESDGSSGSQP
SDDRVCDDED DDDDDKRILP LHFPKEHTYQ AYMKIQDISP VLSNKVNLRD LQESIDTLIG
NLERELNKNK LNVGY
//
