ID   A0A1S3P9R9_SALSA        Unreviewed;      1109 AA.
AC   A0A1S3P9R9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Rho GTPase-activating protein SYDE2-like isoform X4 {ECO:0000313|RefSeq:XP_014024338.1};
GN   Name=LOC106584049 {ECO:0000313|RefSeq:XP_014024338.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014024338.1};
RN   [1] {ECO:0000313|RefSeq:XP_014024338.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014024338.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014024338.1; XM_014168863.1.
DR   AlphaFoldDB; A0A1S3P9R9; -.
DR   GeneID; 106584049; -.
DR   OrthoDB; 2905108at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa23.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR   PANTHER; PTHR46150:SF1; RHO GTPASE-ACTIVATING PROTEIN SYDE2; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          490..609
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          647..862
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          74..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          271..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          405..484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          864..883
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          907..1052
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..313
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..429
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        947..965
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1001..1027
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1109 AA;  122349 MW;  72745DCA3795AA5B CRC64;
     MADPLRRTLL AKLRGKKSKK GTPAGGYGAA ANGGREALIE NDHSSFANGL DVGGGKAVET
     SLWRPPLNTI TVSKKRNWLQ QSSGRPHHAT DDPRYRLGAE EYNGHGQAPL STLSSSPENL
     NPPGPTLSHP LCLHLPLVRM GHARVAPHSR CVEPTEENDA DDEGEIWYNP IPEDEELELH
     HSHRPTSTPQ VRLMVQTRPQ DPHVPQTRPS REVEAGVRRA LEGCSPNLEG VGESMGGGGG
     ERSQQGIAIR CMGPSLHLQR QMLLACKPQE CPSSSSRATA TAEAPDLAIP GFPPPSSLNP
     AKKGSSLNWS FPDKIKSPRT VRKLSMKMKK LPELSRKLSV KGTPSNNNNS SCNGASASSN
     LETRTQYPKT NYGSEPGPAP PRLSPRGGQG AAASHNVISR YHLDSSVSTQ QSYSKKKNSG
     TSKSASKGGY LSDGDSPELV AKSGKHGSSE AKGGNGKEKD PATGGGEKTG AGGVTRGSGS
     PKLHGTELDI DAFRHYAFTE QPKCTQYISG LMSLHFYGAE DLKPPRFDSR DVYCAIQVDS
     VNKARTALLT CRTTFLDMDH TFNIELENAQ HLKLVVFSWD PTPKKNRVCC YGTVVLPALF
     RVSRSHQLAV KLEPRGLIYV KLNLMEQWQN SLDGGYNGDR EPQMFGVEAW RVVVRENTGL
     MLPLLIEKCI TEIETRGCQV VGLYRLCGSA SVKKELREAF ERDSLGVELC ENTYPDINVI
     TGVLKDYLRE LPYPLITKHL YETVLDSMAQ RPLRIGAGGC ENDPADTEHT VSLLENLPDV
     ERLTLRRLLD HLKLVASHHE VNKMTCQNLA VCFGPVLLSQ RQEASCHSNR VFIDSEELAS
     ALHFKKHIEV LHYLLQLWPV VDPHEKTSSP IPEPPGPADQ LAVPPLRRRK DRPQVLNLSN
     AEMAGVLRPR PGRLDSPSNR YAGDWSRCGE SYFPSPRSRV ENDYADVPSE DMEVTEEELE
     GVEDKGQEGG EEQRQEWLLD RGQAEPATAK QEPLLPEEVM EGPVDVEKEE REAEEERAAE
     RRVEESDGSS GSQPSDDRVC DDEDDDDDDK RILPLHFPKE HTYQAYMKIQ DISPVLSNKV
     NLRDLQESID TLIGNLEREL NKNKLNVGY
//