ID A0A1S3P9W4_SALSA Unreviewed; 2360 AA.
AC A0A1S3P9W4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Desmoplakin-like isoform X2 {ECO:0000313|RefSeq:XP_014024388.1};
GN Name=LOC106584072 {ECO:0000313|RefSeq:XP_014024388.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014024388.1};
RN [1] {ECO:0000313|RefSeq:XP_014024388.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014024388.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, desmosome
CC {ECO:0000256|ARBA:ARBA00004568}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004236}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR RefSeq; XP_014024388.1; XM_014168913.1.
DR GeneID; 106584072; -.
DR OrthoDB; 4322299at2759; -.
DR Proteomes; UP000087266; Chromosome ssa23.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0030057; C:desmosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169:SF26; DESMOPLAKIN; 1.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00681; Plectin; 7.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21019; Spectrin_3; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00250; PLEC; 16.
DR SUPFAM; SSF75399; Plakin repeat; 4.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 452..510
FT /note="Desmoplakin SH3"
FT /evidence="ECO:0000259|Pfam:PF17902"
FT DOMAIN 545..622
FT /note="Desmoplakin spectrin-like"
FT /evidence="ECO:0000259|Pfam:PF18373"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1133..1156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2043..2082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2301..2360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 308..335
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 378..437
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 720..751
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1287..1360
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2360 AA; 265897 MW; 0C7CEE31035A3BB9 CRC64;
MSLYGSQRGL HVSRSIGSRP DLSGGTGQYA QSEVHGGNRY GQEYMDDNTY SYSKTSMGGG
GYGQGQFPLG GLHQKAYILQ GQCQDYLREA EHYLQAGGDS GRGTVEADHY MAMARETIGQ
LKACALDLRQ MGQPNDSVVR SVEMCRDQLT GVHMAINGTM QRRRRGSRGS GAWEEAGWSI
NEAMAWIGHQ KHLIETSQWG DNSADIEQQL ISHSKFHSSI QRSPEVDKAK VELIKKGDKA
NQYALDQEWD TLQKMSHGRS SQLREMQQII EAISRQIMWV NVREEEELVF DWGDKNIDLY
IPKKQESYSK LMSALEEKEK DLNKLKLKVD SLLKNPHPAS DKIEAYMDTL QTQWSWLLQI
TKCIHVHLKE NAAYSEFFKE ANEMYDKLQQ VHENIRKKFT SDRNTPLENL LELLKGLEKE
KERIMENKRQ VQHLVNKSKS IVRLRPRNPE EEKSSIPVIV QALCDFKQDQ KVILKGNEGI
LKDNSQRSKW QVTGPGGLDM LVPSVCLLVP PPNSLGINLA NKNEQYYEAI LSVWNQLYIN
IKSLISWQYY VQDLTRINSL TITMLSRMRP EEYRSILKSL ETHYSEFTHC CHGSEMFKDE
DKRSIESQYT GAHAHYDHLL VQLPAYTAQQ TANEEKIKAE EGARILAAKK EEAKVVATKQ
DHVKKVVVKK KVASVTSQSL TELHELRLRL EGAEAGLTQH IHICLAEDGA HDCGLRITQL
ESVQRDVDSI REEYLRLKER VLKELENMTD SDKATFLHSQ LGLINERLGS LDECSAAYLQ
RLRALRALLQ SVSRAEDIIK VHEARLTEKE TTSLNPAEVG DYRSTLKSMR AELEGKRAVL
VSMETELGKA VHWNGQVGGA FHRCDVDLSR YSEQVNQLSD RWRRIQSQID SRLRDLEGYL
HLLQQYTTTS SVLSEWIGAT RQKHDALQAT KIDSITALNE HLNQQKVLNS EIKGKRESVV
SVLGDTDACV NSIKDYELEL ASYNAGLETL LNIHMKRTML QSPSTKLTEE TTLLQTRYIE
LLTLSGDYNK YLGELHNNME TLKMRNTRID LLEEELRLLK EDIEDHNAKN SSLEEALVRY
RLELSQSQEQ LLSVEEVKRS TALQCSATQD SLASTHSQLK ELQEQVTRLT SLNEEEKRKR
RMADERYGEQ QDEHEQVLRR RQKELEQANW AKMEVEKSVG DREREAEQLR KQLEEEVQRF
KELEQELSKT SCLIQSTQTQ YNKIVMERDA LLLNLKQTNQ DRARSQKLEE ELNHMKVSLE
SELRIKLCLQ EENEKIKKDF LYWKGQYESK EGEMRQFNSE KEKLERERSS LKTEIERLMR
ELRAVEERHK SRLLITQTQF SELTSVRDSL EAELRKLRER PYAFAKHTQT DESGKKDLDP
ATLVFDGVRK MVTAKQLLDC GVINKVTYGQ LLNGQKTVRE VSVDIKLNLK GTGSISGVAV
GRQGKMSLTE AKRDNILSED SAILLLEAQA ATGHIVDPRA NEKMTVQEAC KRGVVYEEDR
ERLLIAEAAC LGYRDPNTTK LLSAGQAMRK GLIDRDTALR MLQAQESVGG IIDPVLSVFL
PKDAAMDRDL IDEDLYRALN QRPECYLDPD TQMGASYVSL KRRCKAEPTT GLLILPAPEK
PMTVKGLRGE VSVTDLMNAN LLEKSDMDQL KEGKLTSQDI EDRLRSYLCG STCIAGVYNE
ANDKTLSIYQ AMKEGLLKPG TTLELLEAQA ASGFMIDPVN NLCLTVADAY TRGLAGPEFK
DKLLSAERAV TGYKDPGTDK IISLFQAMEK GLIEKGHGIR LLEAQIASGG IIDPRHGHRI
EVVTAYKKGY FSKEINQILT DEGDESKGFF DPNNQDNLTY LQLKKRCIID QKTGLVLLSI
NKKKEPPQPT TQKSTLRKRR VVIVDPDTNK EMSVKEAYDK GLIDYEIFLE LSQQECEWEE
ITITTQDGSK RLVIFDRKTE IQYDIRELLE KNVINQSLYD QYRSQMITLT QFADIVTSQT
KANRSSASSS SSSSTSSSKA RAAATSAAAY SSLLSSSTTY SPRITSTSST SIKAEKTSSI
IGSSTIGPSS IGTSIGDGST ITRSTTSSSF TQPDGPSSPS SLKHIASISV SLACPAEAVV
LDGEQSPVGA IFDMEALEKI SISEAHKRGL VDSISAQRLL EAQACTGGIV NPSDGRRLSI
QEASIQGIIE NDMATRLKPA QKAYIGFEDI KCKHKMSAAE AMREKWLPYE AGHRFLEFQF
VTGGLYDPEL GRRRTIKEAL KEGWLDGRGA QKLQDMRQHA KNLTCPKTKL KISYKEAMDN
CLVEENTGVK MLQAASASSR GISSPYNLSA PGSTSGSRTG SRAGSRRGSV DLGSSGSSRR
YSIVSSTTYS RTSFSSSSMS
//
