ID A0A1S3PCK6_SALSA Unreviewed; 551 AA.
AC A0A1S3PCK6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein LOC106584481 {ECO:0000313|RefSeq:XP_014025326.1};
GN Name=LOC106584481 {ECO:0000313|RefSeq:XP_014025326.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014025326.1};
RN [1] {ECO:0000313|RefSeq:XP_014025326.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014025326.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Bcl-2 family.
CC {ECO:0000256|ARBA:ARBA00009458}.
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DR RefSeq; XP_014025326.1; XM_014169851.1.
DR AlphaFoldDB; A0A1S3PCK6; -.
DR STRING; 8030.ENSSSAP00000074006; -.
DR KEGG; sasa:106584481; -.
DR Proteomes; UP000087266; Chromosome ssa23.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd06845; Bcl-2_like; 1.
DR Gene3D; 1.10.437.10; Blc2-like; 1.
DR InterPro; IPR013281; Apop_reg_Mc1.
DR InterPro; IPR036834; Bcl-2-like_sf.
DR InterPro; IPR046371; Bcl-2_BH1-3.
DR InterPro; IPR026298; Bcl-2_fam.
DR InterPro; IPR002475; Bcl2-like.
DR PANTHER; PTHR11256; BCL-2 RELATED; 1.
DR PANTHER; PTHR11256:SF46; INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1; 1.
DR Pfam; PF00452; Bcl-2; 1.
DR PRINTS; PR01866; APOPREGMCL1.
DR PRINTS; PR01862; BCL2FAMILY.
DR SMART; SM00337; BCL; 1.
DR SUPFAM; SSF56854; Bcl-2 inhibitors of programmed cell death; 1.
DR PROSITE; PS50062; BCL2_FAMILY; 1.
PE 3: Inferred from homology;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 285..385
FT /note="Bcl-2 Bcl-2 homology region 1-3"
FT /evidence="ECO:0000259|SMART:SM00337"
SQ SEQUENCE 551 AA; 60715 MW; 5A9C6FEABCA20383 CRC64;
MGGKSYFRME TSPLLRTLEL KGDKDTRKMF LSESALNPAD VGAVTRQDAQ NLYGAGKCDH
PDVPVYTLKE EATITGSDGS PLNVDMSMLS FGSNRQPHHV DPETEPEAFK HSLGACGRHS
KRRRRAAARC SLYDEENFST THDAHGTTGV TVSATQQLDV DEITLVLRPE TSLGPQPEYV
KRACSVTDHG LLLHGAVLYR KGSSAVSIDP EGIMLTCSVT GDTVYRSAYK DLTTKEGEEF
NAKETYHHQT GALDTDTRQL IKCVLGQCTG LLKPRWNESK ALSTMSRVVG QLLEKNRYTY
NGMINTLYVD DRGDDVKFLS AVAHIIFQDG TVNWGRVASL TSFGAAVCQY LKDKGRDNCV
EVAGEEISAY LVTHHKDWLV KHNSWLRSNG FVEFFPVAEP ESRSRNIIMT LVGLAGIGAA
MTLLVISEDD VNICTAVDVL PKGPDNMEAR AQEVDVIARA LVLCFPRVAT SALDELTLRA
PNTLRFSARI WPVFVNSTRA CYQLFKALAL PVSPSPVYIL ELLARGWRYI RPDILGRFIP
MSTGGTCQGQ L
//
