ID   A0A1S3PDW1_SALSA        Unreviewed;       844 AA.
AC   A0A1S3PDW1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
GN   Name=ano5 {ECO:0000313|RefSeq:XP_014025796.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014025796.1};
RN   [1] {ECO:0000313|RefSeq:XP_014025796.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014025796.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU280814}.
CC   -!- SIMILARITY: Belongs to the anoctamin family.
CC       {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU280814}.
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DR   RefSeq; XP_014025796.1; XM_014170321.1.
DR   AlphaFoldDB; A0A1S3PDW1; -.
DR   OrthoDB; 534027at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa23.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR032394; Anoct_dimer.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF23; ANOCTAMIN-5; 1.
DR   Pfam; PF16178; Anoct_dimer; 1.
DR   Pfam; PF04547; Anoctamin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU280814};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU280814}.
FT   TRANSMEM        218..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        377..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        431..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        601..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        654..673
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        762..783
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   DOMAIN          10..204
FT                   /note="Anoctamin dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16178"
FT   DOMAIN          207..797
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
FT   COILED          7..34
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   844 AA;  98760 MW;  28227F460CF974B5 CRC64;
     MFLSFIVVCQ QERRKEYEAN LQKAGLELET EDQSESDDGK TYYVKIHTPW DVLATYADVL
     KIKVPFKAND IPAHKDIPMN WLFTPFRLPN HIMNPEPDYF TSPFNKEKID FFLIDDKETF
     FPPSVRNRIV YYILARCAYH KEDSDDKNKK GIKRLLNNGT YGAAFPLHDS RYWKASRDPN
     SESERFSLYK HWARFFSFFK EQPLNLIRKY YGEKIGIYFA WLGFYTEMLF FAAVVGLICF
     LYGLFTFDDN IWSKEICSEE IGGNIIMCPL CDKTCGYWKL NSTCNSSWQS HMFDNVGTVF
     FAIFMGIWVT LFLEFWKRRQ ARLEYEWDLV DFEEEQQQLQ LRPEYEIKCT SRRLNPVTQE
     EEWVLDRTAA DLVGKVLLCW ATVVLWISLI IACIIGVIAY RLAVYAAFAS IMKDSPTNNI
     QMVGSLITPQ LATSVTASCI NFVIIMILNV MYERVAIWIT DMEIPKTHLE YENKLTVKMF
     LFQFVNYYSS CFYVAFFKGK FVGRPGDYIY MFGWSKLRNE ECDPGGCLIE LTTQLVIVMA
     GKQVWGNIQE ALVPWLLNWW GSRKARSHPE SLYSRWEQDH DLQNFSHLGL FYEYLEMVIQ
     FGFITLFVAS FPLAPLLALL NNIIEVRVDA WKFTTQFRRP VAAKAHSIGA WQEILNGVAV
     FSVVTNAFIV AFTSDMIPRL VYMYAYSPGN DLSMKGYINN SLSVFNISGF SDENRPDDGE
     SPEWFNSSVI TTCRYRDYRY PPGHEKQYTH TMQFWHILAA KLAFIIIMEH VVFMVKFFVA
     WMIPDVPAEV KARVKRERYL IQEYLHNYEV ENLKIQLSHR NDDCSSNPVD YPDISRREVL
     SECL
//