ID A0A1S3PIM9_SALSA Unreviewed; 195 AA.
AC A0A1S3PIM9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Osteoclast-stimulating factor 1 {ECO:0000256|ARBA:ARBA00040640};
GN Name=ostf1 {ECO:0000313|RefSeq:XP_014027518.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014027518.1};
RN [1] {ECO:0000313|RefSeq:XP_014027518.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014027518.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Induces bone resorption, acting probably through a signaling
CC cascade which results in the secretion of factor(s) enhancing
CC osteoclast formation and activity. {ECO:0000256|ARBA:ARBA00037432}.
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DR RefSeq; XP_014027518.1; XM_014172043.1.
DR AlphaFoldDB; A0A1S3PIM9; -.
DR OrthoDB; 25371at2759; -.
DR Proteomes; UP000087266; Chromosome ssa24.
DR CDD; cd11772; SH3_OSTF1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24155; OSTEOCLAST-STIMULATING FACTOR 1; 1.
DR PANTHER; PTHR24155:SF10; OSTEOCLAST-STIMULATING FACTOR 1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..52
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REPEAT 120..152
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 195 AA; 21823 MW; 174EBE3ADA4E5D32 CRC64;
MFTFDPRTPD ELYFEEGDIL YISDTSDSNW WKGTCRGRNG LIPSNYVAEQ AESIDNPMHE
AAKRGNLSWL RECLENKVGI NGLDKAGNTA LYWGCHGGHK DVVEILLGQS NVELNQQNKL
GDTALHAAAW KGYSDIVEML LNKNARMDIK NNEKKLALEM ATNAQCASLI KRKQGGNITR
THSNADEYLD DEDSD
//
