ID   A0A1S3PIX5_SALSA        Unreviewed;       459 AA.
AC   A0A1S3PIX5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Serine/threonine-protein kinase Chk2-like isoform X3 {ECO:0000313|RefSeq:XP_014027551.1};
GN   Name=LOC106585648 {ECO:0000313|RefSeq:XP_014027551.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014027551.1};
RN   [1] {ECO:0000313|RefSeq:XP_014027551.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014027551.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014027551.1; XM_014172076.1.
DR   AlphaFoldDB; A0A1S3PIX5; -.
DR   OrthoDB; 20430at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa24.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd22666; FHA_CHK2; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR   PANTHER; PTHR44167:SF9; SERINE_THREONINE-PROTEIN KINASE CHK2; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|RefSeq:XP_014027551.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transferase {ECO:0000313|RefSeq:XP_014027551.1}.
FT   DOMAIN          36..93
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          138..408
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          419..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..459
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  51962 MW;  7F69712D47D8CD21 CRC64;
     MKNKQHFPRV SRDPISPENL HVPRLIRNPD CVEDDAWFGR HTKCNYSFDV PILRESSRFA
     AYSNKHFRIF REKNIVYVFD NSNNGTFVDG NVIGKGKMLP LANNAVLSLA EERHKVFVFI
     DLMADEQSNL PKELSEKYMI TKKIGVGVCG EVKLAFERAT CKKVALKTIN KNDFPASVGT
     ATRSAEREIQ ILQKIDHPCL IKTKDFFQTD DSYYIVLELM EGGELYDRVK SKQQIKEPIA
     KLYFYQMLKA VEYLHNNGII HRDLKPENVL LSSHDDVCVI KITDFNQSKI LEESALMRTL
     CGTPTYLAPE VFTDAVTVGY SRAVDAWSLG VVLFVCSLPL SLAGYPPFYP DARIGLSVSD
     QITQGIYTFI PSKWDGISDD AKDVVKKLLR VDPNVRLTIE EALQHPWLMD EAMKETAEGI
     MYPKDSRDAD GTADSGDATV ASTGKRSRED EEEQQPTKR
//