ID A0A1S3PIX9_SALSA Unreviewed; 810 AA.
AC A0A1S3PIX9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ARF GTPase-activating protein GIT2-like isoform X3 {ECO:0000313|RefSeq:XP_014027602.1};
GN Name=LOC106585671 {ECO:0000313|RefSeq:XP_014027602.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014027602.1};
RN [1] {ECO:0000313|RefSeq:XP_014027602.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014027602.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014027602.1; XM_014172127.1.
DR AlphaFoldDB; A0A1S3PIX9; -.
DR GeneID; 106585671; -.
DR CTD; 793882; -.
DR OrthoDB; 2877020at2759; -.
DR Proteomes; UP000087266; Chromosome ssa24.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007420; P:brain development; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR047161; GIT-like.
DR InterPro; IPR032352; GIT1/2_CC.
DR InterPro; IPR022018; GIT1_C.
DR InterPro; IPR013724; GIT_SHD.
DR PANTHER; PTHR46097:SF4; ARF GTPASE-ACTIVATING PROTEIN GIT2; 1.
DR PANTHER; PTHR46097; G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF12205; GIT1_C; 1.
DR Pfam; PF16559; GIT_CC; 1.
DR Pfam; PF08518; GIT_SHD; 2.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00555; GIT; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 166..198
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 383..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 438..479
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 404..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 89963 MW; BF9B551DFFFC8C91 CRC64;
MSKRLRNSEL CADCSVPEPR WASVNRGVLI CDECCSVHRS LGRHSSQVRH LTHTPWAPTQ
LQMVQMLYNN SANSIWEHSL LDPASVMSGK RKANPQDKVH PNKTEFIKAK YQMLAFVHRM
PCRDDDSFTA KDLSKQLHSS VRTGNLETCL RLLSLGAQAN FFHPEKGNTP LHVAAKAGQV
FQAELLTVYG ADPGAPDTSA KTPIDYARQA GYLDLADRLV EIQYELTDRL AFYLCGRKPD
HKNGQHFIVP QMADRNISLD LSELAKAAKK KLQSLSNHLF EELAMDVYDE VDRRETDAVW
LATQNHSTLV TDTTVVPFLP VNPEYSSTRN QGRQKLARFN AHEFATLVID ILSDAKRRQL
GNSTTSPKEN VELILKSVSI RRGSEGLDND QPDYDSVASD EDTDQEPPLG KDRTKSLDSD
LSDGPVTVQE FLEVKHALSA SEAKIKQLMK VNSNLSSELR LMQKKLHSLQ SENTSLKRQG
PTTHIYQVPI SSGSEYTDPP SSSPSAMKRR QSARASRPMS MSIYETGSGL KPYLPKGETP
YPEEGIPTLQ PFLPPHMGRG AFVTSSSLPS FPSTLSWSRD ESAQRASKME KWSSMSDGDY
DNTTNDSELE DSGVGRRGRL RSSGWLGEGS SIPELDDLEA EPDSALPSTE DVIRKTEQIT
KNIQDLLRAA QENKHDRPCE GVRRLRHSLG CFSSLVPWAE KAPSPLQPLN LRSPDPAACF
IPCSERIHVA VTEMAALFPK RRRSETVRGP LRLLTSSAFR LQGECQKAVP PEGGPGPDMQ
LVTQQVIQCA YDIAKAAKQL VTITTKENSN
//
