ID A0A1S3PKI5_SALSA Unreviewed; 688 AA.
AC A0A1S3PKI5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};
GN Name=LOC106585937 {ECO:0000313|RefSeq:XP_014028162.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014028162.1};
RN [1] {ECO:0000313|RefSeq:XP_014028162.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Sodium-phosphate symporter. {ECO:0000256|RuleBase:RU363058}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 Na(+)(out) + phosphate(out) = 2 Na(+)(in) + phosphate(in);
CC Xref=Rhea:RHEA:71259, ChEBI:CHEBI:29101, ChEBI:CHEBI:43474;
CC Evidence={ECO:0000256|ARBA:ARBA00035083};
CC -!- SUBCELLULAR LOCATION: Apical cell membrane
CC {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363058}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU363058}.
CC -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC 2.A.20) family. {ECO:0000256|ARBA:ARBA00009916,
CC ECO:0000256|RuleBase:RU363058}.
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DR RefSeq; XP_014028162.1; XM_014172687.1.
DR AlphaFoldDB; A0A1S3PKI5; -.
DR STRING; 8030.ENSSSAP00000054982; -.
DR PaxDb; 8030-ENSSSAP00000054982; -.
DR KEGG; sasa:106585937; -.
DR OrthoDB; 5488632at2759; -.
DR Proteomes; UP000087266; Chromosome ssa24.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR001204; Phos_transporter.
DR PANTHER; PTHR11101; PHOSPHATE TRANSPORTER; 1.
DR PANTHER; PTHR11101:SF80; SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2; 1.
DR Pfam; PF01384; PHO4; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363058};
KW Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW ECO:0000256|RuleBase:RU363058};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Sodium {ECO:0000256|ARBA:ARBA00023201};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363058};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363058};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363058}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 186..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 570..587
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT TRANSMEM 658..685
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363058"
FT REGION 288..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 74193 MW; EC2381E5092CBCD7 CRC64;
MVDLQEYLWM VILGFVIAFI LAFSVGANDV ANSFGTAVGS GVVTLKQACI LASIFETLGS
MLLGAKVGET IRKGIIDVNL YNETVPVLMA GEVSAMVGSA IWQLIASFLK LPISGTHCIV
GSTIGFSMVA IGTKGVQWMQ LVKIVASWFI SPLLSGMMSG FLFFLIRHFI LNQDDPVPNG
LRALPVFYAS TIGINAFSIL YTGAPLLGLE MLPVWAIALI TLAGALVCAA VVWFAVCPWM
RRKIASRIKK ERAALSRISD ESLEQIPEEE EEELPVFKEL PGAKGTDDAV LPLTGGTGGE
SRRGESTGEL NNLANGGTVL PKGRVYGRTH SMTNGTLSMS KSPLSNGSFT FGGEHIRSDG
QVYHTVHKDS GLYKDLLHKI HLGRLEDDHS APTPDNNYRL LRRNNSYTCY TAAICGMPVQ
PLIRSESREA REAREDSEKL VGEGERSGSV SYTKKRVRYD SYSSYCNAVA EAEIEAEEGG
VEMKLASDLG GEEAGAPGAP VPLDDSAEED EGDKDKPTVY LLFHFLQILT ACFGSFAHGG
NDVSNAIGPL VALWMIYEQG GVMQDAATPI WLLFYGGVGI CCGLWVWGRR VIQTMGKDLT
PITPSSGFTI ELASALTVVL ASNIGIPVST THCKVGSVVA VGWIRSKKAV DWRLFRNIFL
AWFVTVPVAG LFSAAVMALF VYGILPYV
//
