ID   A0A1S3PLJ0_SALSA        Unreviewed;      1127 AA.
AC   A0A1S3PLJ0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Formin-like protein 2 isoform X2 {ECO:0000313|RefSeq:XP_014028553.1};
GN   Name=LOC106586162 {ECO:0000313|RefSeq:XP_014028553.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014028553.1};
RN   [1] {ECO:0000313|RefSeq:XP_014028553.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014028553.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
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DR   RefSeq; XP_014028553.1; XM_014173078.1.
DR   AlphaFoldDB; A0A1S3PLJ0; -.
DR   OrthoDB; 471257at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa25.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR010472; FH3_dom.
DR   InterPro; IPR043592; FMNL_animal.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   InterPro; IPR010473; GTPase-bd.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   PANTHER; PTHR45857:SF5; FORMIN-LIKE PROTEIN 2; 1.
DR   Pfam; PF06367; Drf_FH3; 1.
DR   Pfam; PF06371; Drf_GBD; 2.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM01139; Drf_FH3; 1.
DR   SMART; SM01140; Drf_GBD; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          22..476
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          624..1015
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          534..604
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1018..1038
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          398..457
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        542..604
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1127 AA;  127795 MW;  F54F04B7A7CDD961 CRC64;
     MGNAGSMDQQ TDFRGHNMPL KLPMPEPGEL EERFAIVLNS MNLPPDKARL LRQYDNEKKW
     ELICDQERFQ VKNPPHTYIQ KLRGFLDPAA TRKKFRRRVQ ESTQVLRELE ISLRTNHIGW
     VREFLNEENK GLDVLVEYLS FAQYAVTFDG DSVENNPEKL VDKPWSRSIE DLPSPVSGNS
     ISRTGRHSTL RYVLTQADKS RTPSSLKCPK YSQGRCCNAL PSRRTLKNSR LVCKKDDVHV
     CIMCLRAIMN YQYGFNMVMS HPHAVNEIAL SLNNKNPRTK ALVLELLAAV CLVRGGHEII
     LSAFDNFKEV CAETQRFERL MEHFKDMDNN IDFMVACMQF INIVVHSVED MNFRVHLQYD
     FTKLCLDTYL DKLKHTESDK LSVQIQAYLD NVFDVGALLE DAETKNAALE RVEELEENMS
     HMTEKLQDTE NEAMSKIVEL EKQLMTRNKE LDSIREVYKD ANSQVHTLRR MVKEKDEAIQ
     RQCNLEKKIH ELEKQGTMTI QKKCDGDISS LPSPPAPGGP LVAGVPRVYN GGTVSPMGSN
     GVPGMPAPPP PPPPPLVPGI VPNGPLAGLA APPPPPPPPP PPPPPGPMEV SAPLPPPPPP
     MAPPLPGCGS PTVIFNSGLA AVKIKKPIKT KFRLPVFNWV ALKPNQINGT VFNEIDDERI
     LEDLNVDEFE EMFKTKAQGT AIDLIMSKTK VIQKGPNKVA LLDANRAKNM AITLRKVGKA
     PEEICKAIQL FDLRTLSVDY VECLMRFLPT ESEVKIMRQY EKERKPVEAL TDEDRFMMHF
     SKIERLMQKM TIMAFIGNFC ESVQMLTPQL HAVIAASVSI KSSQKLKKIL EIILALGNYM
     NSSKRGAVYG FKLQSLDLLL DTKSTDRKMT LLHYIANVVK EKYQQVNLFY NELHYVEKAA
     AVSLENVLLD VKELQRGMDL TKREYSMHGH NTMLKDFITH NEGKLKKLQD DAKIALDAFD
     EAVKFFGENS KTTPPSVFFP VFVRFVKAYR QAEEDNEQRK RAELMMMEKL LEQEAMLDQE
     DQKSPSHKNT RGRSQQQEVI AELRKKQVKD TGSRHVYEGK DGAIEDIITA LKKNNITKFP
     NVHSRVRNSS NSTPVVVDVS QTWQASLFYL PSLKLPTTEG FIYFILD
//