ID A0A1S3PXR5_SALSA Unreviewed; 4591 AA.
AC A0A1S3PXR5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Plectin isoform X16 {ECO:0000313|RefSeq:XP_014032495.1};
GN Name=LOC100194709 {ECO:0000313|RefSeq:XP_014032495.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014032495.1};
RN [1] {ECO:0000313|RefSeq:XP_014032495.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014032495.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_014032495.1; XM_014177020.1.
DR GeneID; 100194709; -.
DR CTD; 567639; -.
DR OrthoDB; 5321591at2759; -.
DR Proteomes; UP000087266; Chromosome ssa27.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd06503; ATP-synt_Fo_b; 1.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF21; EPIPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 16.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 32.
DR SMART; SM00150; SPEC; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 20..140
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 153..258
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 802..859
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1500..1542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1548..1567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1617..1704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1776..1805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1965..1992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2024..2050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2089..2177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2345..2375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2517..2571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4258..4288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4488..4523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 755..785
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1246..1276
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1342..1436
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2089..2142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2159..2177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4258..4280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4591 AA; 525057 MW; DCA80B7507408FFE CRC64;
MDTARSIQHE ITSLKDERDR VQKKTFTKWV NKHLMKHWRA EAQRHITDLY EDLRDGHNLI
SLLEVLSGET LPRERDVVRN SRLPREKGRM RFHKLQNVQI ALDFLKHRQV KLVNIRNDDI
ADGNPKLTLG LIWTIILHFQ ISDIQVNGQS DDMTAKEKLL LWSQRMVEGY HGMRCDNFTT
SWRDGKLFNA VIHKHRPTLI DMSKVYRQTH VENLEQAFSV AERDLGVTRL LDPEDVDVPH
PDEKSIITYV SSLYDVMPRV PDVQDGVKAN ELELRWQEYY ELVTLLLQWI RHHIIVFEER
KFPTSYEEIE VLWRQFLKFK ETELPAKEAD KNRSKHVYKS FEGAVQVGHV KVPPGYHPID
VEKEWGRLHV AILERERLLR TEFERLERLQ RIVSKVQMES GVCEEQLNQV EGLLQMDVRL
LNSGKPAMHT AEVETDLDKA EGMIRYLFND VQLLKDGRHL QAEQMYRRVY RLHERLVNLR
SEYNLRLKSG VTTTQIPMSQ MQTLQQAPIR VRPELDEVTL RYIQDLLAWV EENQRRVDRG
EWGSDLPTVE SQLGSHRGLH QSVEEFHAKI GRAKADESQL SPVSKGAYRD NLSKLELHYG
KLLSSSKARL RSLDGLHAFV TAATKELMWL NEKEEEEVNY DWSERNTNMT AKKDNYSGLM
KELEHREKRV NSVQVQGDKL LKEGHPAKMT VEAFTAALQT QWSWILQLCC CIESHLKENT
AYFQFFSDVK EAEEKMKKMQ KTMKKKYTCN RNITVTRLED LLQDAVDEKE QLKEFKTHLD
GLNRRAKTIV QLKPRNPATP VKGKLPVQAV CDFKQMELTV HRGEECALLD NSQPYKWKVQ
NPKGSKATVP SICFLVPPTN NDAVSGVSGL DTSHQNLLVL WQMLYVDMKS LMTWQYLMRD
IHLITSWNIT MFKTLRVEEY RLALRNLELH YQEFLRDSQD SQLFGADDRM QVESGYNKAS
QHYEGLLHSV EKGYVSPTGG EQDESECRSY LTKIKDLCLK LEGCETRTVA HLRQPVDKEP
LKACAQRTAE QKKVQSELEG LKKDLTNVAE KTEEVLASPQ QSISNPVLRS ELDITLKKME
HIYSLSSVYL DKLKTIDIVI RSTKGAEDTL KKYEARLRDV NKMPTDEKEV ENYHTQLKTM
RGEAEDDQKT FDNLQVELKK AAAVNERIKL VHSEHNTELE HYRQLVAGLE ERWQVVFAQI
DLRQQELDLL GRQMCAYHES YDWLIRWLCD AKQRQEKIQA MPIGDSKALM QQLAQEKKLL
EEIEKNKDKV EECQKHARAY IDAVKDYELQ VVMYKALVEP LASPLRKTKM ECASDNIIQE
YVTLRTRYSE LMTLTSQYIK FITETQRRLE DEEKATEILK KEERKKLSEM QAELDKQRQL
AEAHAKAIAK AEKEAQELKL KMKEEVSRRE VVKVDSEKQK HNIQQQLHEL KNLSEQEIQS
KSQQVEEALY SHTKIEEEIH IIRIQLETTI KQKATAEAQV QQLRDMAVEA ERLRKVTQEE
AEKLRKQVNE ETQKKRNAEE ELKHKAEAEQ EAAKQKQKAL DEVQKFKMQA EEAERRMKQA
EEEKQRQVMV AEEVAQKSAA TELQTKRMSF NEKAVKLEAS LKQEQDTVIQ LQEQAERLKK
QQEEANKARE EAEKELEKWR QKANEALRLR LQAEEDAHKK SQAQEEAEKQ KEKAQREAKK
RAKAEEAALK QKEMAEKELE KQRKLAEGMA QQKLSAEQEL IRLRADFDHG KQQRSLLDEE
LQRLKNEVNA AVKQRKELED ELAKVRREME VLLQMKSKAE KETMSTTEKS RNLLESEASK
MRQLAEEATK LRSIAEDAKK QRQIAEDEAA RQRGEAEKIL KEKLAAINEA TCLKTEAEIA
LKDKEAENER LRRKAEDEAY QRKILEDQAK QHKQDIDEKI TQLKNTSDSE LERQKKIVEE
TLKQRRVVEE EIRILKLNFE EASTGKLDLE LELNKLKGIA DETHKNKVKA EEESEKLRKH
ALEEENKRKQ AEEKVKKITA AEEEAARQCQ AAQKEVERLK KIAADANKQK EDADKETEKQ
ISLAKEAAQK CSDAEKRAQA VLVKQKEDNL FQGKLKEEFD KAKNLVQEAE KAKEKAEKEA
ALLRQKAEDA EKQKKAAEAE AAKQAKAQGD AERLRMAAEQ EAAKQAEAEA AALKQKQQAD
AEMAKHKKLA EQTVKQKKQV EQELTKVKLR LDETDKQKSV LDEELQRQKD EVSNAVKQKA
QVEDELFKIK VQMEELVKLK LRIENENQRL MSKDKDNTQK FLEEEAENMK KLAEDAARLS
LEAQEAARER QITESELEEQ RALADKMLKE KMQAIQEAAK LKAEAENLQK QKDKAQKQAQ
KLLEDKQQMQ QRFEEETEGF QKSLEAERKR QHEATVEAEK LKLRVTQLSD AQSKAEEEAK
KFKKQADEIR VRLQEKEQHA SEKVIVEKLE VQRLQSSKES DNLRKAIADL QKENEKLQKE
AADLQNKSKE MANAQQEQIK KEKIVLEQTF LTEKQLLLKK EKLIEEEKNK LEKQFEDEVK
KAKDLKDEQD RQRKQMEQEK KKLHATMDAA VKKQKDAEEE MCNKQKEMQD LEKKRLEQEK
LLGEENEKLR EKLQQLSTLK KSATSHTKEM EMQTDEVPED QLIAMTMVGT TKKVFDGSAV
VDGEKKNEES PFSFDGIREK VPASRLHDIG ILNKKDFDKL KKGKTTVKDL SKTEKVKTCL
KGKNSVGGIL TAAKQKMSVY QAMKENKLSP GAATMLLEAQ AASGYIIDPV KNRMLTVDEA
VKEELIGPEL HNKMLSAEKA ATGYKDPYTG DKISLFEAMK KGLVEQDQAF RLLDAQIATG
GIIDPVNSHR VPLQTAYKQG QLDAEMSKTL SNPTDDAKLF IDPSSQESLT YQQLLEKCTP
DAETGLLMLP ITEKATQSDK TYTTEETKYV LTKANISVPF GRFQGKTVTI WEIINSEYFT
EAQRKDLIRQ YKTGKITVEK IIKIVISVVE DKEKGNEIVF DGLRIPVTAA ELLESKILNK
DLFNKLHNGK TTVKEISEME PVKKALRGTH SIAGVIVEST NEKIPFYQAV KEQMLSPETA
LTLLEAQAGT GFVMDPVKNQ KLTVDEAVKS GLVGPEMHEI LMSAERAVNG YKDPYTGKNL
SLFEAMLKDL IKKDQGIRLL EAQLATGGII DPVKSYHIPH DVACKRGYFN DETNKTLSNN
TDETKVFFDP NMWENASYVQ LMNKCVTDEE TGFPFLPLSE KAIQKSKEEH YKSKEEHQYT
EVQIKDALNQ ATMELPYGPF KGRKVTIWEI INSEYITEEQ RIELIRQYRT GTVTIERMIT
IIVTMVDEKE DKKQEKEQAS FEGLRSSVTA SSLFESKIID KATYDQLQQG KKKPKEISGI
DSVRKYLQGT DGQIVGIYMG DSKEKVSIYQ AMKKNILRQN TGLSLLKAQA ATGFIIDPVK
NQRYTVDDAV KAGVVGPEVH EKLLSAEKAV TGYRDPYTGN TISLFQAMKK ELVLREHAIP
LLEAQVATGG IIDPVSSHYV PNDVAFQRGY FNKQMANNFT DPSGDIKAFI DPNNNESSTY
KQLQEKCIRD PDTGLCFLPL SKAEAQSPVE KSYIYTEEMA QTDLTNTQVD IPHQSYAGKV
MTLWDVMGSN LLPEEEKLRL LEQYRLGQIT KERMIIIVIE IIEQREILKG EQSMSCDVIR
RRVTIEELYS SRIIDLQTYN MLKQEKKTIR EVMEMPSVKQ YLFGTGSIAG ILSDSPSKVS
IYQAMKRGLI KPDFAISLLE AQAATGFIID PVKEELLTVD EAVRKGLVGP EIHDKLLSAE
RAVTGYKDPY SGKVISLFQA MKKDLVPEDY ALRLLEAQAS TGGLMDPEYY FHLPTDVAMQ
RGYINKETHD RITDPNSDVQ GYVDPTTEER QSYAQLLKKC KADKESGLRL LSLADRRLLF
KGLRKQITLD ELLRSQIIDQ KTYNDLIEGL ISVEEVSKEV KKYLEGTSCI AGVYVESSKD
RLSIYQAMKK NMIRPGTAFE LLEAQAATGY IIDPIKNLKL NVGEAVKMGV VGSEFKDKLI
SAERAVTGYR EPYSGKNISL FQAMKKGLIL KDHGIRLLEA QIATGGIIDP EESHRLPVEM
AYTRGLFDEE MNGILTDPSD DTKGFFDPNT EENLTYLQLM ERCMIDPETG LALLLLKEKK
RERKTSSKSS VRKRRVVIVD PETGKEMSVY EAYRKGLIDQ QTYMELAEQE CEWEEITISS
SDGVVKSMII DRRSGRQYDI DDAITKGLID QSALDQYRAG TLSITEFADM LSGNITGTRS
RSSSFGSTSS YSSSPAPSIK PPATIWNDPT EETVPVAGIL DTDTLEKVSV TEAMHRNLVD
NITGQRLLEA QACAGGIIDP NTGEKFSVSD AMNMGLVDKI MVDRINLAQK AFNGFEDPRT
KKKMSAAQAL KKGWLYYEAG QRFLEVQYLT GGLIEPEVTG RVPLDVAVNK GTLDARTAQK
LRDVSGYSKY LTCPKTKLKI SYKDAMDRSM IEEGSGLRLL EASSQSSKGL YSPYSVSGSG
SASGSRPDSR TGSRSGSRRG SFDATGSGFS TNFSSSSFSS TSYGRRYNAG LQSGLSMDEL
AQALTSLAMG RNCSSEERIF TTIQPNYSPV A
//
