ID A0A1S3PXS0_SALSA Unreviewed; 4584 AA.
AC A0A1S3PXS0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Plectin isoform X20 {ECO:0000313|RefSeq:XP_014032500.1};
GN Name=LOC100194709 {ECO:0000313|RefSeq:XP_014032500.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014032500.1};
RN [1] {ECO:0000313|RefSeq:XP_014032500.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014032500.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_014032500.1; XM_014177025.1.
DR OrthoDB; 5321591at2759; -.
DR Proteomes; UP000087266; Chromosome ssa27.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd06503; ATP-synt_Fo_b; 1.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF21; EPIPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 16.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 32.
DR SMART; SM00150; SPEC; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 5.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 13..133
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 146..251
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 795..852
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1493..1535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1541..1560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1610..1697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1769..1798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1958..1985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2017..2043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2081..2170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2322..2368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2509..2564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4251..4281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4481..4516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 748..778
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1239..1269
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1335..1429
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2081..2135
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2152..2170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4251..4273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4584 AA; 524295 MW; EFDF1F35E7EDE643 CRC64;
MTQQDIGKYE RDRVQKKTFT KWVNKHLMKH WRAEAQRHIT DLYEDLRDGH NLISLLEVLS
GETLPRERDV VRNSRLPREK GRMRFHKLQN VQIALDFLKH RQVKLVNIRN DDIADGNPKL
TLGLIWTIIL HFQISDIQVN GQSDDMTAKE KLLLWSQRMV EGYHGMRCDN FTTSWRDGKL
FNAVIHKHRP TLIDMSKVYR QTHVENLEQA FSVAERDLGV TRLLDPEDVD VPHPDEKSII
TYVSSLYDVM PRVPDVQDGV KANELELRWQ EYYELVTLLL QWIRHHIIVF EERKFPTSYE
EIEVLWRQFL KFKETELPAK EADKNRSKHV YKSFEGAVQV GHVKVPPGYH PIDVEKEWGR
LHVAILERER LLRTEFERLE RLQRIVSKVQ MESGVCEEQL NQVEGLLQMD VRLLNSGKPA
MHTAEVETDL DKAEGMIRYL FNDVQLLKDG RHLQAEQMYR RVYRLHERLV NLRSEYNLRL
KSGVTTTQIP MSQMQTLQQA PIRVRPELDE VTLRYIQDLL AWVEENQRRV DRGEWGSDLP
TVESQLGSHR GLHQSVEEFH AKIGRAKADE SQLSPVSKGA YRDNLSKLEL HYGKLLSSSK
ARLRSLDGLH AFVTAATKEL MWLNEKEEEE VNYDWSERNT NMTAKKDNYS GLMKELEHRE
KRVNSVQVQG DKLLKEGHPA KMTVEAFTAA LQTQWSWILQ LCCCIESHLK ENTAYFQFFS
DVKEAEEKMK KMQKTMKKKY TCNRNITVTR LEDLLQDAVD EKEQLKEFKT HLDGLNRRAK
TIVQLKPRNP ATPVKGKLPV QAVCDFKQME LTVHRGEECA LLDNSQPYKW KVQNPKGSKA
TVPSICFLVP PTNNDAVSGV SGLDTSHQNL LVLWQMLYVD MKSLMTWQYL MRDIHLITSW
NITMFKTLRV EEYRLALRNL ELHYQEFLRD SQDSQLFGAD DRMQVESGYN KASQHYEGLL
HSVEKGYVSP TGGEQDESEC RSYLTKIKDL CLKLEGCETR TVAHLRQPVD KEPLKACAQR
TAEQKKVQSE LEGLKKDLTN VAEKTEEVLA SPQQSISNPV LRSELDITLK KMEHIYSLSS
VYLDKLKTID IVIRSTKGAE DTLKKYEARL RDVNKMPTDE KEVENYHTQL KTMRGEAEDD
QKTFDNLQVE LKKAAAVNER IKLVHSEHNT ELEHYRQLVA GLEERWQVVF AQIDLRQQEL
DLLGRQMCAY HESYDWLIRW LCDAKQRQEK IQAMPIGDSK ALMQQLAQEK KLLEEIEKNK
DKVEECQKHA RAYIDAVKDY ELQVVMYKAL VEPLASPLRK TKMECASDNI IQEYVTLRTR
YSELMTLTSQ YIKFITETQR RLEDEEKATE ILKKEERKKL SEMQAELDKQ RQLAEAHAKA
IAKAEKEAQE LKLKMKEEVS RREVVKVDSE KQKHNIQQQL HELKNLSEQE IQSKSQQVEE
ALYSHTKIEE EIHIIRIQLE TTIKQKATAE AQVQQLRDMA VEAERLRKVT QEEAEKLRKQ
VNEETQKKRN AEEELKHKAE AEQEAAKQKQ KALDEVQKFK MQAEEAERRM KQAEEEKQRQ
VMVAEEVAQK SAATELQTKR MSFNEKAVKL EASLKQEQDT VIQLQEQAER LKKQQEEANK
AREEAEKELE KWRQKANEAL RLRLQAEEDA HKKSQAQEEA EKQKEKAQRE AKKRAKAEEA
ALKQKEMAEK ELEKQRKLAE GMAQQKLSAE QELIRLRADF DHGKQQRSLL DEELQRLKNE
VNAAVKQRKE LEDELAKVRR EMEVLLQMKS KAEKETMSTT EKSRNLLESE ASKMRQLAEE
ATKLRSIAED AKKQRQIAED EAARQRGEAE KILKEKLAAI NEATCLKTEA EIALKDKEAE
NERLRRKAED EAYQRKILED QAKQHKQDID EKITQLKNTS DSELERQKKI VEETLKQRRV
VEEEIRILKL NFEEASTGKL DLELELNKLK GIADETHKNK VKAEEESEKL RKHALEEENK
RKQAEEKVKK ITAAEEEAAR QCQAAQKEVE RLKKIAADAN KQKEDADKET EKQISLAKEA
AQKCSDAEKR AQAVLVKQKE DNLFQGKLKE EFDKAKNLVQ EAEKAKEKAE KEAALLRQKA
EDAEKQKKAA EAEAAKQAKA QGDAERLRMA AEQEAAKQAE AEAAALKQKQ QADAEMAKHK
KLAEQTVKQK KQVEQELTKV KLRLDETDKQ KSVLDEELQR QKDEVSNAVK QKAQVEDELF
KIKVQMEELV KLKLRIENEN QRLMSKDKDN TQKFLEEEAE NMKKLAEDAA RLSLEAQEAA
RERQITESEL EEQRALADKM LKEKMQAIQE AAKLKAEAEN LQKQKDKAQK QAQKLLEDKQ
QMQQRFEEET EGFQKSLEAE RKRQHEATVE AEKLKLRVTQ LSDAQSKAEE EAKKFKKQAD
EIRVRLQEKE QHASEKVIVE KLEVQRLQSS KESDNLRKAI ADLQKENEKL QKEAADLQNK
SKEMANAQQE QIKKEKIVLE QTFLTEKQLL LKKEKLIEEE KNKLEKQFED EVKKAKDLKD
EQDRQRKQME QEKKKLHATM DAAVKKQKDA EEEMCNKQKE MQDLEKKRLE QEKLLGEENE
KLREKLQQLS TLKKSATSHT KEMEMQTDEV PEDQLIAMTM VGTTKKVFDG SAVVDGEKKN
EESPFSFDGI REKVPASRLH DIGILNKKDF DKLKKGKTTV KDLSKTEKVK TCLKGKNSVG
GILTAAKQKM SVYQAMKENK LSPGAATMLL EAQAASGYII DPVKNRMLTV DEAVKEELIG
PELHNKMLSA EKAATGYKDP YTGDKISLFE AMKKGLVEQD QAFRLLDAQI ATGGIIDPVN
SHRVPLQTAY KQGQLDAEMS KTLSNPTDDA KLFIDPSSQE SLTYQQLLEK CTPDAETGLL
MLPITEKATQ SDKTYTTEET KYVLTKANIS VPFGRFQGKT VTIWEIINSE YFTEAQRKDL
IRQYKTGKIT VEKIIKIVIS VVEDKEKGNE IVFDGLRIPV TAAELLESKI LNKDLFNKLH
NGKTTVKEIS EMEPVKKALR GTHSIAGVIV ESTNEKIPFY QAVKEQMLSP ETALTLLEAQ
AGTGFVMDPV KNQKLTVDEA VKSGLVGPEM HEILMSAERA VNGYKDPYTG KNLSLFEAML
KDLIKKDQGI RLLEAQLATG GIIDPVKSYH IPHDVACKRG YFNDETNKTL SNNTDETKVF
FDPNMWENAS YVQLMNKCVT DEETGFPFLP LSEKAIQKSK EEHYKSKEEH QYTEVQIKDA
LNQATMELPY GPFKGRKVTI WEIINSEYIT EEQRIELIRQ YRTGTVTIER MITIIVTMVD
EKEDKKQEKE QASFEGLRSS VTASSLFESK IIDKATYDQL QQGKKKPKEI SGIDSVRKYL
QGTDGQIVGI YMGDSKEKVS IYQAMKKNIL RQNTGLSLLK AQAATGFIID PVKNQRYTVD
DAVKAGVVGP EVHEKLLSAE KAVTGYRDPY TGNTISLFQA MKKELVLREH AIPLLEAQVA
TGGIIDPVSS HYVPNDVAFQ RGYFNKQMAN NFTDPSGDIK AFIDPNNNES STYKQLQEKC
IRDPDTGLCF LPLSKAEAQS PVEKSYIYTE EMAQTDLTNT QVDIPHQSYA GKVMTLWDVM
GSNLLPEEEK LRLLEQYRLG QITKERMIII VIEIIEQREI LKGEQSMSCD VIRRRVTIEE
LYSSRIIDLQ TYNMLKQEKK TIREVMEMPS VKQYLFGTGS IAGILSDSPS KVSIYQAMKR
GLIKPDFAIS LLEAQAATGF IIDPVKEELL TVDEAVRKGL VGPEIHDKLL SAERAVTGYK
DPYSGKVISL FQAMKKDLVP EDYALRLLEA QASTGGLMDP EYYFHLPTDV AMQRGYINKE
THDRITDPNS DVQGYVDPTT EERQSYAQLL KKCKADKESG LRLLSLADRR LLFKGLRKQI
TLDELLRSQI IDQKTYNDLI EGLISVEEVS KEVKKYLEGT SCIAGVYVES SKDRLSIYQA
MKKNMIRPGT AFELLEAQAA TGYIIDPIKN LKLNVGEAVK MGVVGSEFKD KLISAERAVT
GYREPYSGKN ISLFQAMKKG LILKDHGIRL LEAQIATGGI IDPEESHRLP VEMAYTRGLF
DEEMNGILTD PSDDTKGFFD PNTEENLTYL QLMERCMIDP ETGLALLLLK EKKRERKTSS
KSSVRKRRVV IVDPETGKEM SVYEAYRKGL IDQQTYMELA EQECEWEEIT ISSSDGVVKS
MIIDRRSGRQ YDIDDAITKG LIDQSALDQY RAGTLSITEF ADMLSGNITG TRSRSSSFGS
TSSYSSSPAP SIKPPATIWN DPTEETVPVA GILDTDTLEK VSVTEAMHRN LVDNITGQRL
LEAQACAGGI IDPNTGEKFS VSDAMNMGLV DKIMVDRINL AQKAFNGFED PRTKKKMSAA
QALKKGWLYY EAGQRFLEVQ YLTGGLIEPE VTGRVPLDVA VNKGTLDART AQKLRDVSGY
SKYLTCPKTK LKISYKDAMD RSMIEEGSGL RLLEASSQSS KGLYSPYSVS GSGSASGSRP
DSRTGSRSGS RRGSFDATGS GFSTNFSSSS FSSTSYGRRY NAGLQSGLSM DELAQALTSL
AMGRNCSSEE RIFTTIQPNY SPVA
//
