ID A0A1S3Q3X3_SALSA Unreviewed; 476 AA.
AC A0A1S3Q3X3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Transcription factor 7-like 2 isoform X30 {ECO:0000313|RefSeq:XP_014034642.1};
GN Name=LOC106589326 {ECO:0000313|RefSeq:XP_014034642.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014034642.1};
RN [1] {ECO:0000313|RefSeq:XP_014034642.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014034642.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TCF/LEF family.
CC {ECO:0000256|ARBA:ARBA00006569}.
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DR RefSeq; XP_014034642.1; XM_014179167.1.
DR AlphaFoldDB; A0A1S3Q3X3; -.
DR GeneID; 106589326; -.
DR OrthoDB; 5351131at2759; -.
DR Proteomes; UP000087266; Chromosome ssa28.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd21996; HMG-box_TCF7-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR InterPro; IPR027397; Catenin-bd_sf.
DR InterPro; IPR013558; CTNNB1-bd_N.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR024940; TCF/LEF.
DR PANTHER; PTHR10373; TRANSCRIPTION FACTOR 7 FAMILY MEMBER; 1.
DR PANTHER; PTHR10373:SF32; TRANSCRIPTION FACTOR 7-LIKE 2; 1.
DR Pfam; PF08347; CTNNB1_binding; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM01366; c-clamp; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 332..400
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 332..400
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 476 AA; 53545 MW; 3577C9CE70245A22 CRC64;
MPQLNGGGGD DLGANDEMIS FKDEGEQEEK ISENLSAERD LADVKSSLVN ESETNQNSSS
DSEAERRPPP RSETFRDKTR ESLEEAAKRQ DGGLFKSPPY PGYPFIMIPD LTSPYLPNGS
LSPTARTYLQ MKWPLLDVNH GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
ITYSNEHFTP GNPPPHLQGD VDPKTGIPRP PQHPDISPYY PLSPGSVGQL PHPLGWLVPQ
QGQPVYPITT GGFRHPYPTA LTVNASMQSF LSSRFPHHMV PPHHSLHQTG IPHPAIVTPN
VKQESSHSDI GLNSSKHQDS KKEDEKKKQP HIKKPLNAFM LYMKEMRAKV VAECTLKESA
AINQILGRRW HALTREEQAK YYELARKERQ LHMQLYPGWS ARDNYGKKKK RKRDKQPGEG
NEHREYFPNP CLSLPPITDL SAPKKCRARF GLDQQNNWCG PCRCKYPKEV SCLVRA
//
